2019
Core Outcome Measures for Chronic Musculoskeletal Pain Research: Recommendations from a Veterans Health Administration Work Group
Kroenke K, Krebs EE, Turk D, Von Korff M, Bair MJ, Allen KD, Sandbrink F, Cheville AL, DeBar L, Lorenz KA, Kerns RD. Core Outcome Measures for Chronic Musculoskeletal Pain Research: Recommendations from a Veterans Health Administration Work Group. Pain Medicine 2019, 20: 1500-1508. PMID: 30615172, DOI: 10.1093/pm/pny279.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyBiomedical ResearchChronic PainDelphi TechniqueDepressionHumansMusculoskeletal PainOutcome Assessment, Health CarePain ManagementPain MeasurementPatient Health QuestionnairePatient Reported Outcome MeasuresPhysical Functional PerformancePsychometricsSleepUnited StatesUnited States Department of Veterans AffairsConceptsCore Outcome MeasuresOutcome measuresPain intensityPatient-reported global impressionBrief Pain Inventory Interference ScaleChronic musculoskeletal pain disordersMusculoskeletal pain disordersChronic musculoskeletal painPatient Health QuestionnaireNumerical rating scaleVeterans Health AdministrationCommon outcome measuresGeneralized anxiety disorderMusculoskeletal painPain disordersChronic painGlobal ImpressionPhysical functionHealth QuestionnairePhysical functioningSleep ScaleDepression ScaleOutcomes Information SystemPain researchHealth Administration
2010
Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations
Dworkin RH, Turk DC, Peirce-Sandner S, Baron R, Bellamy N, Burke LB, Chappell A, Chartier K, Cleeland CS, Costello A, Cowan P, Dimitrova R, Ellenberg S, Farrar JT, French JA, Gilron I, Hertz S, Jadad AR, Jay GW, Kalliomäki J, Katz NP, Kerns RD, Manning DC, McDermott MP, McGrath PJ, Narayana A, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Reeve BB, Rhodes T, Sampaio C, Simpson DM, Stauffer JW, Stucki G, Tobias J, White RE, Witter J. Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations. Pain 2010, 149: 177-193. PMID: 20207481, DOI: 10.1016/j.pain.2010.02.018.Peer-Reviewed Original ResearchConceptsChronic pain clinical trialsPain clinical trialsClinical trialsPrimary efficacy analysisChronic pain trialsDemonstration of efficacyIMMPACT recommendationsResearch design considerationsAnalgesic effectPain trialsChronic painEfficacy analysisTypes of trialsConsensus meetingTreatment groupsNew interventionsTrue lackTrialsTrial phaseEfficacyMethodological weaknessesAssay sensitivityTreatmentSubstantial variabilityParticipant selection
2006
Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendations
Turk DC, Dworkin RH, Burke LB, Gershon R, Rothman M, Scott J, Allen RR, Atkinson J, Chandler J, Cleeland C, Cowan P, Dimitrova R, Dionne R, Farrar JT, Haythornthwaite JA, Hertz S, Jadad AR, Jensen MP, Kellstein D, Kerns RD, Manning DC, Martin S, Max MB, McDermott MP, McGrath P, Moulin DE, Nurmikko T, Quessy S, Raja S, Rappaport BA, Rauschkolb C, Robinson JP, Royal MA, Simon L, Stauffer JW, Stucki G, Tollett J, von Stein T, Wallace MS, Wernicke J, White RE, Williams AC, Witter J, Wyrwich KW. Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendations. Pain 2006, 125: 208-215. PMID: 17069973, DOI: 10.1016/j.pain.2006.09.028.Peer-Reviewed Original ResearchHigher levels of pain readiness to change and more positive affect reduce pain reports – A weekly assessment study on arthritis patients
Strand EB, Kerns RD, Christie A, Haavik-Nilsen K, Klokkerud M, Finset A. Higher levels of pain readiness to change and more positive affect reduce pain reports – A weekly assessment study on arthritis patients. Pain 2006, 127: 204-213. PMID: 16997472, DOI: 10.1016/j.pain.2006.08.015.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAffectAgedAged, 80 and overArthritis, RheumatoidAttitude to HealthFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePainPain MeasurementSurveys and QuestionnairesPersistent pain and uncomfortable sensations in persons with multiple sclerosis
Hadjimichael O, Kerns RD, Rizzo MA, Cutter G, Vollmer T. Persistent pain and uncomfortable sensations in persons with multiple sclerosis. Pain 2006, 127: 35-41. PMID: 16949751, DOI: 10.1016/j.pain.2006.07.015.Peer-Reviewed Original ResearchConceptsSevere painMultiple sclerosisUncomfortable sensationsPersistent painNorth American Research CommitteeMultiple pain sitesLevel of painManagement of painConstancy of painExperience of painPain sitesModerate painPain severityPain intensityEnjoyment of lifeIntense painPatient RegistryMS populationHigh prevalencePainSmall studyHealthcare providersHealthcare systemSclerosisPositive association
2005
Core outcome measures for chronic pain clinical trials: IMMPACT recommendations
Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, Kerns RD, Stucki G, Allen RR, Bellamy N, Carr DB, Chandler J, Cowan P, Dionne R, Galer BS, Hertz S, Jadad AR, Kramer LD, Manning DC, Martin S, McCormick CG, McDermott MP, McGrath P, Quessy S, Rappaport BA, Robbins W, Robinson JP, Rothman M, Royal MA, Simon L, Stauffer JW, Stein W, Tollett J, Wernicke J, Witter J. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain 2005, 113: 9-19. PMID: 15621359, DOI: 10.1016/j.pain.2004.09.012.Peer-Reviewed Original Research