2016
Research design considerations for single-dose analgesic clinical trials in acute pain
Cooper SA, Desjardins PJ, Turk DC, Dworkin RH, Katz NP, Kehlet H, Ballantyne JC, Burke LB, Carragee E, Cowan P, Croll S, Dionne RA, Farrar JT, Gilron I, Gordon DB, Iyengar S, Jay GW, Kalso EA, Kerns RD, McDermott MP, Raja SN, Rappaport BA, Rauschkolb C, Royal MA, Segerdahl M, Stauffer JW, Todd KH, Vanhove GF, Wallace MS, West C, White RE, Wu C. Research design considerations for single-dose analgesic clinical trials in acute pain. Pain 2016, 157: 288-301. PMID: 26683233, DOI: 10.1097/j.pain.0000000000000375.Peer-Reviewed Original ResearchConceptsClinical trialsEarly phase clinical trialsAcute pain studiesAcute pain trialsPain clinical trialsAnalgesic clinical trialsPhase clinical trialsShort-duration trialsPostoperative painAcute painPain trialsPain assessmentStudy design factorsPain studiesDental impactionStudy designTrialsPainAssessment measuresResearch design considerationsPlaceboSurgeryBunionectomyDifferent settings
2009
Mood and Attitude Predict Pain Outcomes Following Arthroscopic Knee Surgery
Rosenberger PH, Kerns R, Jokl P, Ickovics JR. Mood and Attitude Predict Pain Outcomes Following Arthroscopic Knee Surgery. Annals Of Behavioral Medicine 2009, 37: 70-76. PMID: 19169766, DOI: 10.1007/s12160-008-9078-z.Peer-Reviewed Original ResearchConceptsArthroscopic knee surgeryPain severityPain outcomesPain interferenceKnee surgeryBody mass indexExtent of osteoarthritisPreoperative moodPreoperative depressionKnee osteoarthritisMass indexClinical variablesSurgeryDaily functioningSeveritySignificant predictorsLongitudinal studyPainRegression analysisOsteoarthritisOutcomesImportant predictorDepressionPotential relationshipImportant outcomes