2022
Taking ACTION to Reduce Pain: a Randomized Clinical Trial of a Walking-Focused, Proactive Coaching Intervention for Black Patients with Chronic Musculoskeletal Pain
Burgess DJ, Hagel Campbell E, Hammett P, Allen KD, Fu SS, Heapy A, Kerns RD, Krein SL, Meis LA, Bangerter A, Cross LJS, Do T, Saenger M, Taylor BC. Taking ACTION to Reduce Pain: a Randomized Clinical Trial of a Walking-Focused, Proactive Coaching Intervention for Black Patients with Chronic Musculoskeletal Pain. Journal Of General Internal Medicine 2022, 37: 3585-3593. PMID: 35132545, PMCID: PMC9585120, DOI: 10.1007/s11606-021-07376-2.Peer-Reviewed Original ResearchConceptsBlack patientsUsual careSecondary outcomesPain intensityPrimary outcomeChronic painIntervention participantsVA health care systemMasked outcome assessmentChronic musculoskeletal painMental health comorbiditiesChronic pain outcomesAverage daily stepsTelephone coaching sessionsMain MeasuresPrimary outcomesCoaching interventionHealth care systemResultsThe interventionHealth comorbiditiesMusculoskeletal painPain outcomesSevere chronicPain interferenceGlobal ImpressionMeasuresPrimary outcomes
2021
Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV
Oldfield BJ, Li Y, Vickers-Smith R, Becker WC, Barry DT, Crystal S, Gordon KS, Kerns RD, Rentsch CT, Marshall BDL, Edelman EJ. Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV. AIDS Care 2021, 34: 1053-1063. PMID: 34114904, PMCID: PMC8664891, DOI: 10.1080/09540121.2021.1939851.Peer-Reviewed Original ResearchConceptsOpioid useHigh dosesSelf-reported opioid useVeterans Aging Cohort StudyHigh-dose opioidsMean daily doseAging Cohort StudyHigh-dose benzodiazepinesNational prospective cohortOpioid doseOpioid receiptCohort studyFoot painProspective cohortDaily doseIndependent predictorsChronic painPain interferenceClinical variablesClinical correlatesNational cohortMultinomial logistic regressionPWHLogistic regressionOpioids
2020
Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study.
Edelman EJ, Li Y, Barry D, Brennan Braden J, Crystal S, Kerns RD, Gaither JR, Gordon KS, Manhapra A, Merlin JS, Moore BA, Oldfield BJ, Park LS, Rentsch CT, Skanderson M, Williams EC, Justice AC, Tate JP, Becker WC, Marshall BDL. Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 26-36. PMID: 32267658, PMCID: PMC7147724, DOI: 10.1097/qai.0000000000002310.Peer-Reviewed Original ResearchConceptsOpioid useOpioid use trajectoriesCohort studyPain interferenceSelf-reported opioid useVeterans Aging Cohort StudyVeterans Health Administration sitesInfrequent useOpioid use frequencyMarijuana useAging Cohort StudyNational cohort studyEvidence-based treatmentsGroup-based trajectory modelsProspective cohortBaseline factorsIllness severityMultivariable analysisBenzodiazepine medicationVA carePsychoactive medicationsPrescription painkillersPsychiatric symptomsHeroin useMultinomial logistic regressionInternet‐Based Pain Self‐Management for Veterans: Feasibility and Preliminary Efficacy of the Pain EASE Program
Higgins DM, Buta E, Williams DA, Halat A, Bair MJ, Heapy AA, Krein SL, Rajeevan H, Rosen MI, Kerns RD. Internet‐Based Pain Self‐Management for Veterans: Feasibility and Preliminary Efficacy of the Pain EASE Program. Pain Practice 2020, 20: 357-370. PMID: 31778281, DOI: 10.1111/papr.12861.Peer-Reviewed Original ResearchConceptsChronic low back painSelf-management programPain interferencePreliminary efficacyInternet-based self-management programPhase IPost-baseline assessmentLow back painPain Self-ManagementPhase IIPreliminary efficacy studyTechnology-delivered interventionsModerate painSecondary outcomesPain intensityBack painAverage ageEfficacy studiesDepression symptomsSubject improvementExpert panelSelf-ManagementSubject changesEASE programWeeksCognitive Behavioral Therapy for the Management of Multiple Sclerosis–Related Pain
Gromisch ES, Kerns RD, Czlapinski R, Beenken B, Otis J, Lo AC, Beauvais J. Cognitive Behavioral Therapy for the Management of Multiple Sclerosis–Related Pain. International Journal Of MS Care 2020, 22: 8-14. PMID: 32123523, PMCID: PMC7041614, DOI: 10.7224/1537-2073.2018-023.Peer-Reviewed Original ResearchCognitive behavioral therapyMultiple sclerosisDepressive symptom severityPain severityBehavioral therapyStandard carePain interferenceSymptom severityModerate pain severityHelpful adjunctive treatmentAdjunctive treatmentPrimary outcomeTreatment satisfactionEffective treatmentTreatment groupsPainEducation-based programsDaily functioningTherapySeverityBehavioral goalsSclerosisSignificant differencesTreatmentCare
2019
High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans.
Banerjee G, Edelman EJ, Barry DT, Crystal S, Gordon KS, Gordon AJ, Gaither JR, Green TC, Kerns RD, Manhapra A, Moore BA, Fiellin DA, Marshall BDL. High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans. Pain 2019, 160: 2126-2135. PMID: 31145217, PMCID: PMC6699915, DOI: 10.1097/j.pain.0000000000001606.Peer-Reviewed Original ResearchConceptsHigh-dose opioid prescriptionsOpioid prescriptionsHeroin useCohort studyPrior receiptHepatitis C virus (HCV) infection statusLong-term opioid prescriptionsPast-year heroin useVeterans Aging Cohort StudyHigh-dose opioidsOpioid-prescribing patternsProspective cohort studyAging Cohort StudyOpioid use disorderCurrent national guidelinesUnhealthy alcohol useUnited States veteransUnited States military veteransVirus infection statusPosttraumatic stress disorderOpioid receiptPrescribed opioidsPain interferenceCox regressionStates veteransPersonal Resource Profiles of Individuals With Chronic Pain: Sociodemographic and Pain Interference Differences
Mun CJ, Davis MC, Molton IR, Karoly P, Suk HW, Ehde DM, Tennen H, Kerns RD, Jensen MP. Personal Resource Profiles of Individuals With Chronic Pain: Sociodemographic and Pain Interference Differences. Rehabilitation Psychology 2019, 64: 245-262. PMID: 30688480, PMCID: PMC6737933, DOI: 10.1037/rep0000261.Peer-Reviewed Original ResearchConceptsPain interferenceChronic painChronic pain conditionsSubgroup of individualsPain conditionsPain intensityPain acceptanceBaseline differencesSleep qualityDepressive symptomsNeuromuscular diseasePainPersonal resource variablesAnnual income levelSociodemographic differencesDaily diariesImportant associationGroup differencesSubgroupsFibromyalgiaRobust associationSocial supportLatent profile analysisBaselinePresent study
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot study
2016
Non‐medical use of prescription opioids is associated with heroin initiation among US veterans: a prospective cohort study
Banerjee G, Edelman EJ, Barry DT, Becker WC, Cerdá M, Crystal S, Gaither JR, Gordon AJ, Gordon KS, Kerns RD, Martins SS, Fiellin DA, Marshall BD. Non‐medical use of prescription opioids is associated with heroin initiation among US veterans: a prospective cohort study. Addiction 2016, 111: 2021-2031. PMID: 27552496, PMCID: PMC5056813, DOI: 10.1111/add.13491.Peer-Reviewed Original ResearchConceptsMultivariable Cox regression modelsNon-medical useCox regression modelHeroin initiationPrescription opioidsHeroin useCohort studyUS veteransOpioid use disorder diagnosisVeterans Aging Cohort StudyProspective cohort studyAging Cohort StudyIllicit opioid usePrimary care clinicsPrimary outcome measureStrong risk factorPost-traumatic stress disorderUninfected veteransUninfected patientsOpioid useRegression modelsCare clinicsPain interferencePrior diagnosisPrimary exposureAssociation of Pain With Physical Function, Depressive Symptoms, Fatigue, and Sleep Quality Among Veteran and non-Veteran Postmenopausal Women
Patel KV, Cochrane BB, Turk DC, Bastian LA, Haskell SG, Woods NF, Zaslavsky O, Wallace RB, Kerns RD. Association of Pain With Physical Function, Depressive Symptoms, Fatigue, and Sleep Quality Among Veteran and non-Veteran Postmenopausal Women. The Gerontologist 2016, 56: s91-s101. PMID: 26768395, PMCID: PMC5881612, DOI: 10.1093/geront/gnv670.Peer-Reviewed Original ResearchConceptsExtreme pain interferencePain interferencePhysical functionPain severitySleep qualityDepressive symptomsHealth initiativesStudy participantsWorse physical functionAssociation of painWomen's Health InitiativeNon-veteran womenObservational study participantsLimited physical functioningVeteran statusHealth care servicesPostmenopausal womenLess painPhysical functioningOlder veteransHigh incidencePainCare servicesNumber of womenComorbid symptomsAssociation between pain outcomes and race and opioid treatment: Retrospective cohort study of Veterans
Burgess DJ, Gravely AA, Nelson DB, Bair MJ, Kerns RD, Higgins DM, Farmer MM, Partin MR. Association between pain outcomes and race and opioid treatment: Retrospective cohort study of Veterans. The Journal Of Rehabilitation Research And Development 2016, 53: 13-24. PMID: 26933921, DOI: 10.1682/jrrd.2014.10.0252.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyIndex visitOpioid prescriptionsPain outcomesCohort studyMusculoskeletal painPain treatmentPain interferenceBenefits of opioidsElectronic medical record dataGreater pain interferencePharmacologic pain treatmentsChronic noncancer painVeterans Affairs patientsChronic musculoskeletal painMedical record dataNoncancer painOpioid treatmentMost patientsVA patientsVA SurveyAlternative treatmentPatientsSignificant associationPain
2015
National Dissemination of Cognitive-Behavioral Therapy for Chronic Pain in Veterans
Stewart MO, Karlin BE, Murphy JL, Raffa SD, Miller SA, McKellar J, Kerns RD. National Dissemination of Cognitive-Behavioral Therapy for Chronic Pain in Veterans. The Clinical Journal Of Pain 2015, 31: 722-729. PMID: 25171637, DOI: 10.1097/ajp.0000000000000151.Peer-Reviewed Original ResearchConceptsPain-related outcomesCBT-CPQuality of lifeCognitive behavioral therapyHealth care systemVeteran patientsChronic painVeterans Affairs Health Care SystemPatient-reported pain intensityVA health care systemCare systemTherapeutic alliancePain-related cognitionsPain intensityTreat analysisPain interferencePain catastrophizingPatient outcomesSpecialty settingsOverall distressTraining programPatientsWeekly consultationEffect of trainingNational disseminationTrauma, Social Support, Family Conflict, and Chronic Pain in Recent Service Veterans: Does Gender Matter?
Driscoll MA, Higgins DM, Seng EK, Buta E, Goulet JL, Heapy AA, Kerns RD, Brandt CA, Haskell SG. Trauma, Social Support, Family Conflict, and Chronic Pain in Recent Service Veterans: Does Gender Matter? Pain Medicine 2015, 16: 1101-1111. PMID: 25930005, DOI: 10.1111/pme.12744.Peer-Reviewed Original ResearchConceptsChronic painDepressive symptom severityPain interferencePain severitySymptom severitySocial supportCombat exposurePerpetuation of painChildhood interpersonal traumaMilitary sexual traumaInterpersonal traumaHigh prevalencePainDepressive symptomsWomen veteransService veteransTraumatic life eventsTraumatic sexual experiencesTraumaBaseline surveyMarital statusSeverityFamily conflictVeteransSexual traumaSpecific and General Therapeutic Mechanisms in Cognitive Behavioral Treatment of Chronic Pain
Burns JW, Nielson WR, Jensen MP, Heapy A, Czlapinski R, Kerns RD. Specific and General Therapeutic Mechanisms in Cognitive Behavioral Treatment of Chronic Pain. Journal Of Consulting And Clinical Psychology 2015, 83: 1-11. PMID: 24979313, DOI: 10.1037/a0037208.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPain intensityChronic painPatient expectationsPosttreatment changesPotential treatment mechanismsStandard cognitive behavioral therapyPre-post changesPain interferenceCognitive-behavioral treatmentSignificant linear trendTherapeutic mechanismDepressive symptomsDocument efficacyPainCBT conditionBehavioral treatmentBehavioral therapyComparable improvementWeeksCBT mechanismsOutcomesTreatmentSignificant quadratic trendTreatment mechanisms
2012
Pain Coping but Not Readiness to Change Is Associated With Pretreatment Pain-related Functioning
Finan PH, Burns JW, Jensen MP, Nielson WR, Kerns RD. Pain Coping but Not Readiness to Change Is Associated With Pretreatment Pain-related Functioning. The Clinical Journal Of Pain 2012, 28: 687-692. PMID: 22688600, DOI: 10.1097/ajp.0b013e3182400867.Peer-Reviewed Original Research
2011
Nonmedical use of prescription opioids and pain in veterans with and without HIV
Barry DT, Goulet JL, Kerns RK, Becker WC, Gordon AJ, Justice AC, Fiellin DA. Nonmedical use of prescription opioids and pain in veterans with and without HIV. Pain 2011, 152: 1133-1138. PMID: 21354703, PMCID: PMC3086805, DOI: 10.1016/j.pain.2011.01.038.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnalgesics, OpioidChi-Square DistributionCohort StudiesFemaleHealth SurveysHIV InfectionsHumansLogistic ModelsMaleMental DisordersMiddle AgedOdds RatioOpioid-Related DisordersPainPain MeasurementPrescriptionsPsychiatric Status Rating ScalesRetrospective StudiesSelf ReportSurveys and QuestionnairesVeterans HealthYoung AdultConceptsHuman immunodeficiency virusPrescription opioidsComponent summaryHIV statusPain interferenceUse disordersForm Health Survey Mental Component SummarySF-12 Physical Component SummaryVeterans Aging Cohort StudyNonmedical usePharmacy record dataAlcohol Use Disorders Identification Test (AUDIT) scoresAging Cohort StudyPhysical component summaryMental component summaryOpioid use disorderMedian participant ageDrug use disordersLegitimate medical reasonsPast-month cigarette useChi-squared testU.S. military veteransHepatitis COpioid prescriptionsCohort study
2009
Mood and Attitude Predict Pain Outcomes Following Arthroscopic Knee Surgery
Rosenberger PH, Kerns R, Jokl P, Ickovics JR. Mood and Attitude Predict Pain Outcomes Following Arthroscopic Knee Surgery. Annals Of Behavioral Medicine 2009, 37: 70-76. PMID: 19169766, DOI: 10.1007/s12160-008-9078-z.Peer-Reviewed Original ResearchConceptsArthroscopic knee surgeryPain severityPain outcomesPain interferenceKnee surgeryBody mass indexExtent of osteoarthritisPreoperative moodPreoperative depressionKnee osteoarthritisMass indexClinical variablesSurgeryDaily functioningSeveritySignificant predictorsLongitudinal studyPainRegression analysisOsteoarthritisOutcomesImportant predictorDepressionPotential relationshipImportant outcomes
2008
The Association of Sexual Trauma with Persistent Pain in a Sample of Women Veterans Receiving Primary Care
Haskell SG, Papas RK, Heapy A, Reid MC, Kerns RD. The Association of Sexual Trauma with Persistent Pain in a Sample of Women Veterans Receiving Primary Care. Pain Medicine 2008, 9: 710-717. PMID: 18565005, DOI: 10.1111/j.1526-4637.2008.00460.x.Peer-Reviewed Original ResearchConceptsPain-related interferencePresence of painPersistent painPain intensityWomen veteransClinic populationChronic conditionsHealth centersSexual traumaDepressive symptom severity scoresMultivariate logistic regression analysisOngoing pain problemsMultivariate linear regression analysisMore chronic conditionsGreater pain intensityDepressive symptom scoresSymptom severity scoresWomen's health centersLogistic regression analysisRegression analysisDepression symptom severityHigh rateMilitary sexual harassmentPain interferenceRoutine appointments
2007
Using Interactive Voice Response to Measure Pain and Quality of Life
Heapy A, Sellinger J, Higgins D, Chatkoff D, Bennett T, Kerns R. Using Interactive Voice Response to Measure Pain and Quality of Life. Pain Medicine 2007, 8: s145-s154. DOI: 10.1111/j.1526-4637.2007.00378.x.Peer-Reviewed Original ResearchTransdermal fentanylQuality of lifeVA Connecticut Healthcare SystemChronic noncancer painRandomized clinical trialsAverage painNoncancer painOral opioidsPain controlChronic painPain interferenceInteractive voice response technologyMedication adherenceProspective dataClinical trialsParticipant adherenceSleep qualityPainSide effectsTreatment dataLarger studyRelative efficacyInteractive voice responseIVR technologyHealthcare systemMeta-Analysis of Psychological Interventions for Chronic Low Back Pain
Hoffman BM, Papas RK, Chatkoff DK, Kerns RD. Meta-Analysis of Psychological Interventions for Chronic Low Back Pain. Health Psychology 2007, 26: 1-9. PMID: 17209691, DOI: 10.1037/0278-6133.26.1.1.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painPain intensityBack painD effect sizesPsychological interventionsInclusion criteriaHealth care provider visitsComputer-aided literature searchHealth-related qualityPain-related interferenceHealth care utilizationRandom-effects modelCohen's d effect sizesMinimal publication biasEffect sizeSelf-regulatory treatmentPain medicationProvider visitsActive control conditionCare utilizationPain interferenceCompensation statusClinical trialsPositive short-term effects