2020
All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors
Gordon K, Manhapra A, Crystal S, Dziura J, Edelman E, Skanderson M, Kerns R, Justice A, Tate J, Becker W. All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors. Drug And Alcohol Dependence 2020, 216: 108291. PMID: 33011662, PMCID: PMC7644145, DOI: 10.1016/j.drugalcdep.2020.108291.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseCause mortalityLong-term opioid therapyTime-updated Cox regressionStrong dose-response relationshipUnnatural deathsEquivalent daily doseDose-response relationshipOpioid doseOpioid therapyUninfected patientsOpioid useDaily doseCox regressionMortality outcomesTherapy doseHigh doseMale veteransOverdose fatalitiesOverdose mortalityPLWHMortalityHIVPatientsDose
2014
Trends and Regional Variation in Opioid Overdose Mortality Among Veterans Health Administration Patients, Fiscal Year 2001 to 2009
Bohnert AS, Ilgen MA, Trafton JA, Kerns RD, Eisenberg A, Ganoczy D, Blow FC. Trends and Regional Variation in Opioid Overdose Mortality Among Veterans Health Administration Patients, Fiscal Year 2001 to 2009. The Clinical Journal Of Pain 2014, 30: 605-612. PMID: 24281278, DOI: 10.1097/ajp.0000000000000011.Peer-Reviewed Original ResearchConceptsVeterans Health Administration patientsOpioid prescribingOverdose ratesNational Health SystemOverdose mortalityNational Death Index recordsHealth systemRate of overdosesPrescription opioid overdosesVeterans Health AdministrationOpioid overdose mortalityOpioid overdose deathsOverdose prevention strategiesPopulation-level associationPatient populationMedical recordsOpioid overdosesSemisynthetic opioidsOverdose deathsGeneral populationOpioid policyPrevention strategiesOpioidsHealth AdministrationPrescribing