2008
Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer
Nadler Y, Camp RL, Schwartz C, Rimm DL, Kluger HM, Kluger Y. Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer. Clinical Cancer Research 2008, 14: 4455-4462. PMID: 18628459, PMCID: PMC5849429, DOI: 10.1158/1078-0432.ccr-07-5268.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAurora Kinase BAurora KinasesBiomarkers, TumorBlotting, WesternBreast NeoplasmsCell Line, TumorFemaleHistory, 17th CenturyHumansImage Processing, Computer-AssistedImmunohistochemistryKaplan-Meier EstimatePrognosisProtein Serine-Threonine KinasesTissue Array AnalysisConceptsBreast cancerB expressionAurora B expressionBreast tumorsHigh AuroraEarly-stage breast cancerHER-2/neuProgesterone receptor expressionSubset of patientsPopulation of patientsIndependent prognostic markerHigh nuclear gradePrimary breast tumorsCy5-conjugated antibodiesPathologic variablesPrognostic roleMultivariable analysisProspective studyNuclear gradePrognostic markerReceptor expressionClinical developmentPatientsPredictive roleCancer
2005
Microsatellite instability and gene mutations in transforming growth factor‐beta type II receptor are absent in small bowel carcinoid tumors
Kidd M, Eick G, Shapiro MD, Camp RL, Mane SM, Modlin IM. Microsatellite instability and gene mutations in transforming growth factor‐beta type II receptor are absent in small bowel carcinoid tumors. Cancer 2005, 103: 229-236. PMID: 15599934, DOI: 10.1002/cncr.20750.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBase Pair MismatchBase SequenceCarcinoid TumorCase-Control StudiesCohort StudiesDNA Mutational AnalysisFemaleGene Expression Regulation, NeoplasticGenomic InstabilityHumansIntestinal NeoplasmsIntestine, SmallMaleMicrosatellite RepeatsMiddle AgedMolecular Sequence DataMutationProbabilityPrognosisProtein Serine-Threonine KinasesReceptor, Transforming Growth Factor-beta Type IIReceptors, Transforming Growth Factor betaReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityConceptsSmall bowel carcinoidsSmall bowel carcinoid tumorsCarcinoid tumorsGrowth factor beta type II receptorMicrosatellite instabilityMismatch repair genesType II receptorLiver metastasesNormal mucosaII receptorsBAT-26Carcinoid tumor metastasisVariable expressionMicrosatellite stable phenotypeRepair genes