2017
Long-term outcomes of tissue-based ACTH-antibody assay-guided transsphenoidal resection of pituitary adenomas in Cushing disease.
Erfe JM, Perry A, McClaskey J, Inzucchi SE, James WS, Eid T, Bronen RA, Mahajan A, Huttner A, Santos F, Spencer D. Long-term outcomes of tissue-based ACTH-antibody assay-guided transsphenoidal resection of pituitary adenomas in Cushing disease. Journal Of Neurosurgery 2017, 129: 629-641. PMID: 29027854, DOI: 10.3171/2017.3.jns162245.Peer-Reviewed Original ResearchConceptsTranssphenoidal resectionMRI studiesCushing's diseaseCortisol levelsLong-term corticosteroid therapyUrinary free cortisol levelsLong-term disease remissionLong-term patient outcomesResults Fourteen patientsLong-term outcomesPostoperative MRI studiesSurgical tumor samplesFree cortisol levelsPreoperative MRI studiesPrecise tumor localizationACTH antibodiesPituitary microCorticosteroid therapyStudy patientsDisease remissionFourteen patientsRemission rateRetrospective reviewTreatment failureCure rate
2014
Brainstem melanomas presenting as a cavernous malformation
Lu AY, Patel AR, Kuzmik GA, Atsina K, Bronen RA, Jabbour PM, Hasan DM, Vortmeyer AO, Welch BG, Bulsara KR. Brainstem melanomas presenting as a cavernous malformation. Neurochirurgie 2014, 60: 184-187. PMID: 24856047, DOI: 10.1016/j.neuchi.2014.02.005.Peer-Reviewed Case Reports and Technical NotesConceptsCavernous malformationsClinical courseWhole-brain radiation therapyAcute pontine hemorrhageRight dorsal midbrainWhole brain radiationAggressive clinical courseRepeat hemorrhageMelanoma presentingSurgical resectionBrainstem hemorrhagePontine hemorrhagePoor prognosisTreatment modalitiesHemorrhagic lesionsRadiation therapyDorsal midbrainStereotactic radiosurgeryMelanoma lesionsLesionsHemorrhageMelanomaMalformationsResectionBrainstem
2006
Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease
Basso M, Yang J, Warren L, MacAvoy MG, Varma P, Bronen RA, van Dyck CH. Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease. Psychiatry Research 2006, 146: 251-261. PMID: 16524704, DOI: 10.1016/j.pscychresns.2006.01.007.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingAD patientsAmygdaloid volumesAlzheimer's diseaseHealthy controlsHippocampal volumeAlzheimer's Disease Assessment Scale-CognitionMedial temporal lobe atrophyTemporal lobe atrophyOlder healthy subjectsADAS-Cog subscaleHealthy control samplesLobe atrophyAD groupHealthy subjectsAnalysis of covarianceMRI studiesProdromal stagePatientsResonance imagingMildest symptomsNeuropsychological assessmentNeuropsychological performanceHippocampusDisease
2005
Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease
Basso M, Gelernter J, Yang J, MacAvoy MG, Varma P, Bronen RA, van Dyck CH. Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease. Neurobiology Of Aging 2005, 27: 1416-1424. PMID: 16182410, DOI: 10.1016/j.neurobiolaging.2005.08.002.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseAD patientsAPOE epsilon4AD groupImportant genetic risk factorApolipoprotein E epsilon4Regional brain atrophyAPOE epsilon4 alleleElderly control subjectsNormal elderly control subjectsGenetic risk factorsAmygdaloid volumesBrain atrophyControl subjectsEpsilon4 carriersRisk factorsEpsilon4 alleleHippocampal volumeEpsilon4 doseAnalysis of covarianceDisease severityPatientsEpsilon4AmygdalaAtrophy
2000
Choroid plexus changes after temporal lobectomy.
Saluja S, Sato N, Kawamura Y, Coughlin W, Putman C, Spencer D, Sze G, Bronen R. Choroid plexus changes after temporal lobectomy. American Journal Of Neuroradiology 2000, 21: 1650-3. PMID: 11039344, PMCID: PMC8174865.Peer-Reviewed Original ResearchConceptsTemporal lobectomyChoroid plexusPostoperative changesResection siteNormal postoperative changesRecurrent brain tumorsContrast-enhanced T1-weighted imagesPresence of infectionContrast-enhanced MR imagingDegree of enhancementT1-weighted imagesChoroid plexus changesHippocampal sclerosisRecurrent tumorsIntractable epilepsyNodular patternPathologic changesPostoperative siteLobectomyBrain tumorsEnhancement patternSurgical manipulationPlexusMorphologic changesMR imagingMR Imaging and Histologic Features of Subinsular Bright Spots on T2-weighted MR Images: Virchow-Robin Spaces of the Extreme Capsule and Insular Cortex
Song C, Kim J, Kier E, Bronen R. MR Imaging and Histologic Features of Subinsular Bright Spots on T2-weighted MR Images: Virchow-Robin Spaces of the Extreme Capsule and Insular Cortex. Radiology 2000, 214: 671-677. PMID: 10715028, DOI: 10.1148/radiology.214.3.r00mr17671.Peer-Reviewed Original ResearchConceptsInsular cortexExtreme capsuleMR imagingControl subjectsBrain specimensPerivascular spacesFormalin-fixed brain specimensFluid-attenuated inversion recovery sequencesVirchow-Robin spacesT2-weighted magnetic resonance imagesCoronal T2-weighted imagesT2-weighted imagesCoronal MR imagesHigh signal intensityT2-weighted MR imagesInversion recovery sequenceHistologic featuresHistologic findingsCerebrospinal fluidMR imagesPatientsWhite matterPathologic conditionsGross anatomic inspectionMagnetic resonance images
1997
Postoperative changes in the brain: MR imaging findings in patients without neoplasms.
Sato N, Bronen R, Sze G, Kawamura Y, Coughlin W, Putman C, Spencer D. Postoperative changes in the brain: MR imaging findings in patients without neoplasms. Radiology 1997, 204: 839-46. PMID: 9280269, DOI: 10.1148/radiology.204.3.9280269.Peer-Reviewed Original ResearchConceptsPostoperative MR imagesPostoperative changesDural enhancementEnhancement patternThin linear enhancementContrast enhancement patternMagnetic resonance imagingMR imagesSurgical marginsTemporal lobectomyNeoplastic changesExtraaxial fluidIntracranial airContrast material-enhanced MR imagesDay 5Day 51Day 30Resonance imagingSurgeryBrainPatientsTime courseContrast enhancementLinear enhancementDays
1996
Comparison of technetium-99m-HMPAO and technetium-99m-ECD cerebral SPECT images in Alzheimer's disease.
van Dyck CH, Lin CH, Smith EO, Wisniewski G, Cellar J, Robinson R, Narayan M, Bennett A, Delaney RC, Bronen RA, Hoffer PB. Comparison of technetium-99m-HMPAO and technetium-99m-ECD cerebral SPECT images in Alzheimer's disease. Journal Of Nuclear Medicine 1996, 37: 1749-55. PMID: 8917168.Peer-Reviewed Original ResearchConceptsControl subjectsAD patientsAlzheimer's diseaseAge-matched control subjectsBrain structuresBrain perfusion agentHigh diagnostic accuracyTechnetium-99mCysteinate dimerHealthy subjectsPatientsDiagnostic groupsPerfusion agentDiagnostic accuracyDiseaseSignificant differencesDiagnostic toolSPECT imagesSubjectsPurported advantagesCharacteristic analysisSignificant interactionCerebral imagesAnalysis of varianceCount density
1994
CT-Guided Percutaneous Insertion of Interstitial Radiotherapy Catheters in Head and Neck Tumors
Bronen R, Lee G, Son Y, Healy G, Meli J, Sasaki C. CT-Guided Percutaneous Insertion of Interstitial Radiotherapy Catheters in Head and Neck Tumors. Journal Of Computer Assisted Tomography 1994, 18: 163. PMID: 8282876, DOI: 10.1097/00004728-199401000-00039.Peer-Reviewed Original ResearchConceptsNeck tumorsPercutaneous insertionRadiation therapyDetailed anatomical localizationPalliative radiation therapyTherapy catheterInterstitial radiation therapyPrecise percutaneous placementInoperable headTumor sizePercutaneous placementCT guidanceSurgical placementAnatomical localizationCatheterTumorsPatientsVascular structuresTherapyCTHeadPainPlacement
1992
Efficacy of Gadoteridol for Magnetic Resonance Imaging of the Brain and Spine
RUNGE V, BRONEN R, DAVIS K. Efficacy of Gadoteridol for Magnetic Resonance Imaging of the Brain and Spine. Investigative Radiology 1992, 27: s33. PMID: 1506150, DOI: 10.1097/00004424-199208001-00006.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingEfficacy of gadoteridolResonance imagingCentral nervous system pathologyMulticenter clinical trialNervous system pathologyIntravenous contrast agentsMagnetic resonance scansVisualization of pathologyRadiologic evidencePostcontrast scansSpinal lesionsClinical trialsIntravenous administrationPathologic lesionsSpinal pathologySystem pathologyResonance scansPrecontrast imagesSpinal casesIntracranial casesPathologyGadoteridolLesion bordersPatients
1989
MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis.
Sze G, Soletsky S, Bronen R, Krol G. MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis. American Journal Of Roentgenology 1989, 153: 1039-49. PMID: 2801423, DOI: 10.2214/ajr.153.5.1039.Peer-Reviewed Original ResearchConceptsContrast-enhanced CTAbnormal meningeal enhancementMeningeal carcinomatosisMeningeal enhancementInner tableMR imagingGroup of patientsDiffuse meningeal enhancementContrast-enhanced MRAbnormal findingsLeptomeningeal tumorSubdural hematomaInflammatory conditionsGroup 2Postoperative defectsGroup 1CarcinomatosisSkull lesionsGroup 3Pathologic conditionsNormal meningesMeningesPatientsCranial meningesHead scansMR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis.
Sze G, Soletsky S, Bronen R, Krol G. MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis. American Journal Of Neuroradiology 1989, 10: 965-75. PMID: 2505542, PMCID: PMC8335283.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBrainBrain DiseasesCarcinomaChildChild, PreschoolContrast MediaFemaleGadoliniumGadolinium DTPAHumansImage EnhancementInfantMagnetic Resonance ImagingMaleMeningeal NeoplasmsMeningesMiddle AgedOrganometallic CompoundsPentetic AcidProspective StudiesRadiographyRetrospective StudiesConceptsContrast-enhanced CTAbnormal meningeal enhancementMeningeal carcinomatosisMeningeal enhancementInner tableMR imagingGroup of patientsDiffuse meningeal enhancementContrast-enhanced MRAbnormal findingsLeptomeningeal tumorSubdural hematomaInflammatory conditionsGroup 2Postoperative defectsGroup 1CarcinomatosisSkull lesionsGroup 3Pathologic conditionsNormal meningesMeningesPatientsCranial meningesHead scans
1984
Diffuse lymphoid follicles of the colon associated with colonic carcinoma.
Bronen R, Glick S, Teplick S. Diffuse lymphoid follicles of the colon associated with colonic carcinoma. American Journal Of Roentgenology 1984, 142: 105-9. PMID: 6606941, DOI: 10.2214/ajr.142.1.105.Peer-Reviewed Original Research