2006
Increased Number of Subcortical Hyperintensities on MRI in Children and Adolescents With Tourettes Syndrome, Obsessive-Compulsive Disorder, and Attention Deficit Hyperactivity Disorder
Amat JA, Bronen RA, Saluja S, Sato N, Zhu H, Gorman DA, Royal J, Peterson BS. Increased Number of Subcortical Hyperintensities on MRI in Children and Adolescents With Tourettes Syndrome, Obsessive-Compulsive Disorder, and Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2006, 163: 1106-1108. PMID: 16741215, PMCID: PMC2367225, DOI: 10.1176/ajp.2006.163.6.1106.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderCerebral hyperintensitiesObsessive-compulsive disorderHealthy comparison subjectsTourette syndromeDeficit hyperactivity disorderMagnetic resonance imagesComparison subjectsHyperactivity disorderT2-weighted magnetic resonance imagesChildhood neuropsychiatric disordersSubcortical injuryPatient groupSubcortical hyperintensitiesHyperintensitySyndromeDiagnostic groupsChildhood diagnosisNeuropsychiatric disordersDisordersResonance imagesSubcortexSubjectsChildrenAdolescents
2003
Basal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome
Peterson BS, Thomas P, Kane MJ, Scahill L, Zhang H, Bronen R, King RA, Leckman JF, Staib L. Basal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome. JAMA Psychiatry 2003, 60: 415-424. PMID: 12695320, DOI: 10.1001/archpsyc.60.4.415.Peer-Reviewed Original ResearchConceptsBasal ganglia volumesBasal gangliaCaudate nucleus volumeTourette syndromeGanglia volumesObsessive-compulsive disorderLenticular nucleus volumesTic symptomsNucleus volumeGilles dePathophysiology of TSPrior neuroleptic exposureHealthy control subjectsSeverity of ticsComorbid obsessive-compulsive disorderGreat clinical relevanceAttention-deficit/hyperactivity disorder (ADHD) symptomsHyperactivity disorder symptomsRepeated-measures analysisNeuroleptic exposureControl subjectsFunctional disturbancesTrait abnormalityClinical relevanceGanglia
1996
Three cases of symptom change in Tourette's syndrome and obsessive-compulsive disorder associated with paediatric cerebral malignancies.
Peterson B, Bronen R, Duncan C. Three cases of symptom change in Tourette's syndrome and obsessive-compulsive disorder associated with paediatric cerebral malignancies. Journal Of Neurology Neurosurgery & Psychiatry 1996, 61: 497. PMID: 8937345, PMCID: PMC1074048, DOI: 10.1136/jnnp.61.5.497.Peer-Reviewed Case Reports and Technical NotesConceptsGilles de la Tourette's syndromeObsessive-compulsive disorderCerebral malignanciesTourette syndromeTumor progressionNeurobiology of OCDLa Tourette's syndromeImportant neural substrateChart reviewNeuropsychiatric symptomsTic symptomsTumor locationSpecialty clinicCorpus callosumRadiographic documentationSymptom generationLimbic systemCaudate nucleusIntracranial lesionsSymptom changeBrain regionsSymptom severitySyndromeVentral striatumMalignancy