Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders
Atzmony L, Ugwu N, Hamilton C, Paller A, Zech L, Antaya R, Choate K. Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders. Pediatric Dermatology 2022, 39: 903-907. PMID: 35853659, PMCID: PMC9712156, DOI: 10.1111/pde.15094.Peer-Reviewed Original ResearchConceptsInflammatory linear verrucous epidermal nevusVerrucous epidermal nevusEpidermal nevusCARD14 mutationsHotspot mutationsLinear verrucous epidermal nevusPathogenesis-directed therapyCohort of patientsErythematous scaly plaquesRare skin diseaseLines of BlaschkoSomatic pathogenic variantsNSDHL mutationsHistopathological evaluationInflammatory disordersScaly plaquesHistopathologic evaluationHistopathological criteriaLinear porokeratosisSkin lesionsAffected skinPatientsSkin diseasesClinical descriptorsHeterogenous groupToxic epidermal necrolysis‐like acute graft‐versus‐host disease in pediatric bone marrow transplant patients: Case series and review of the literature
Song J, Huang JT, del Carmen Fraile Alonso M, Antaya RJ, Price HN, Funk T, Francois RA, Shah SD. Toxic epidermal necrolysis‐like acute graft‐versus‐host disease in pediatric bone marrow transplant patients: Case series and review of the literature. Pediatric Dermatology 2022, 39: 889-895. PMID: 35730149, DOI: 10.1111/pde.15069.Peer-Reviewed Original ResearchConceptsToxic epidermal necrolysisHematopoietic stem cell transplantCase seriesAcute graftHost diseaseTransplant patientsSkin symptomsPediatric bone marrow transplant patientsBone marrow transplant patientsMulti-institutional case seriesMarrow transplant patientsStem cell transplantBone marrow transplantationGVHD involvementGVHD prophylaxisEpidermal necrolysisPain medicationConcurrent medicationsCulprit medicationGeneralized erythrodermaBSA involvementInfection prophylaxisMedian ageMultidisciplinary carePediatric patients