2016
Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women
Pineda-Belmontes CP, Hernández-Ramírez RU, Hernández-Alcaraz C, Cebrián ME, López-Carrillo L. Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women. Salud Pública De México 2016, 58: 220-227. PMID: 27557380, DOI: 10.21149/spm.v58i2.7791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArsenicArsenicalsBreast NeoplasmsCarrier ProteinsCase-Control StudiesChromatography, High Pressure LiquidEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMass SpectrometryMethylationMiddle AgedPolymerase Chain ReactionPolymorphism, Single NucleotidePPAR gammaRiskRNA-Binding ProteinsYoung AdultConceptsRisk of BCBreast cancerArsenic methylation capacityPolymerase chain reactionMethylation capacityMexican womenBreast cancer riskUrinary arsenic speciesCancer riskPresence of polymorphismsPPAR gammaPolymorphisms of interestUrine samplesGenetic polymorphismsChain reactionWomenHigh-performance liquid chromatographyRiskPolymorphismMethylation ratioSignificant interactionAssociationLiquid chromatography
2014
Arsenic methylation capacity is associated with breast cancer in northern Mexico
López-Carrillo L, Hernández-Ramírez RU, Gandolfi AJ, Ornelas-Aguirre JM, Torres-Sánchez L, Cebrian ME. Arsenic methylation capacity is associated with breast cancer in northern Mexico. Toxicology And Applied Pharmacology 2014, 280: 53-59. PMID: 25062773, DOI: 10.1016/j.taap.2014.07.013.Peer-Reviewed Original ResearchConceptsPrimary methylation indexBC riskSecondary methylation indexHospital-based case-control studyMethylation indexMethylation capacityHigher BC riskBreast cancer incidenceCase-control studyRisk of BCBiological exposure indexArsenic methylation capacityMetabolite percentagesDietary factorsCancer incidenceBreast cancerIAs metabolismMost womenTotal urinaryReproductive historyBC carcinogenesisInter-individual variationWomenExposure indexRisk