2018
Central and Peripheral Biomarkers of Stress Response for Addiction Risk and Relapse Vulnerability
Milivojevic V, Sinha R. Central and Peripheral Biomarkers of Stress Response for Addiction Risk and Relapse Vulnerability. Trends In Molecular Medicine 2018, 24: 173-186. PMID: 29396148, PMCID: PMC6511993, DOI: 10.1016/j.molmed.2017.12.010.Peer-Reviewed Original ResearchConceptsSubstance use disordersTreatment of SUDsDevelopment of SUDHigh relapse rateFunctional brain alterationsCentral stress responseAdrenal axis markersStress response measuresRelapse ratePeripheral biomarkersClinical symptomatologyBrain alterationsUse disordersCandidate biomarkersAutonomic responsesRelapse vulnerabilityPutative biomarkersAddiction riskStress responseBiomarkersTreatmentResponsePathophysiologySymptomatologyPrevention
1994
Effects of ethanol on the acoustic startle reflex in humans
Grillon C, Sinha R, O'Malley S. Effects of ethanol on the acoustic startle reflex in humans. Psychopharmacology 1994, 114: 167-171. PMID: 7846199, DOI: 10.1007/bf02245459.Peer-Reviewed Original ResearchConceptsEffects of ethanolStartle responsePrepulse inhibitionPrepulse stimulusStartle reflexHealthy normal subjectsAcoustic startle reflexAcoustic startle responseAcute ethanolSensorimotor reactivityNormal subjectsStartle amplitudeStartle reactivitySeparate daysReflex experimentsReflexStartle probesInhibitionStimuliPlaceboResponse