2024
S143 Traumatic Events, Chronic Pain, and Multiple Substance Use in Women With Poly-Substance Use Disorder
Fogelman N, Tate M, Wemm S, Vacey E, Bera S, Hermes G, Swain J, Fox H, Sinha R. S143 Traumatic Events, Chronic Pain, and Multiple Substance Use in Women With Poly-Substance Use Disorder. Drug And Alcohol Dependence 2024, 260: 110254. DOI: 10.1016/j.drugalcdep.2023.110254.Peer-Reviewed Original Research
2023
Chronic pain, chronic stress and substance use: overlapping mechanisms and implications
Schaffer J, Fogelman N, Seo D, Sinha R. Chronic pain, chronic stress and substance use: overlapping mechanisms and implications. Frontiers In Pain Research 2023, 4: 1145934. PMID: 37415830, PMCID: PMC10320206, DOI: 10.3389/fpain.2023.1145934.Peer-Reviewed Original ResearchChronic painChronic stressSubstance useSubstance misuseCommon reasons adultsCommon pathophysiologic processChronic pain pathologiesMedial prefrontal circuitsPrefrontal cortex dysfunctionPrescription opioidsPain pathologiesPathophysiologic processesPainBrain areasBiologic underpinningsMedical careReasons adultsEnormous burdenNeural circuitryPrefrontal circuitsVentromedial prefrontal cortex dysfunctionPsychobiological processesIndividual wellnessWellnessRisk
2022
Neural correlates linking trauma and physical symptoms
Choi J, Martins J, Hwang S, Sinha R, Seo D. Neural correlates linking trauma and physical symptoms. Psychiatry Research Neuroimaging 2022, 327: 111560. PMID: 36327865, PMCID: PMC9757618, DOI: 10.1016/j.pscychresns.2022.111560.Peer-Reviewed Original ResearchConceptsPhysical symptomsFunctional magnetic resonance imagingTrauma patientsLateral prefrontal cortexPrefrontal cortexPhysical symptom frequencyPain-related disordersMagnetic resonance imagingNeural correlatesPhysical health symptomsChronic painHealthy controlsTrauma groupSymptom frequencyDorsal striatumGreater physical symptomsSensorimotor areasCurrent studyHippocampal responsesVentromedial prefrontal cortexHealth symptomsHippocampal functionResonance imagingSymptomsUnderlying neurological mechanisms