Multiple bloodmeals enhance dissemination of arboviruses in three medically relevant mosquito genera
Ferdous Z, Dieme C, Sproch H, Kramer L, Ciota A, Brackney D, Armstrong P. Multiple bloodmeals enhance dissemination of arboviruses in three medically relevant mosquito genera. Parasites & Vectors 2024, 17: 432. PMID: 39427222, PMCID: PMC11490111, DOI: 10.1186/s13071-024-06531-y.Peer-Reviewed Original ResearchConceptsAedes aegyptiMidgut infection ratesMultiple bloodmealsVector competence of Aedes aegyptiVirus vectorsLaboratory vector competence studiesVector competence studiesMosquito generaFeeding regimenBiting midgesCulex quinquefasciatusPost-infectionOropouche virusWest Nile virusBloodmealVirus disseminationVector competenceEscape barrierFeeding behaviorDissemination of arbovirusesAedes albopictus mosquitoesAedes triseriatusAedesFemale mosquitoesNile virusInvestigating the dose-dependency of the midgut escape barrier using a mechanistic model of within-mosquito dengue virus population dynamics
Johnson R, Stopard I, Byrne H, Armstrong P, Brackney D, Lambert B. Investigating the dose-dependency of the midgut escape barrier using a mechanistic model of within-mosquito dengue virus population dynamics. PLOS Pathogens 2024, 20: e1011975. PMID: 38557892, PMCID: PMC11008821, DOI: 10.1371/journal.ppat.1011975.Peer-Reviewed Original ResearchConceptsBasal lamina layersInfection dynamicsYellow fever virusEpidemics of severe diseaseMidgut escape barrierDengue virusVirus population dynamicsAmount of virusEstablishment of infectionDose-dependentlyMosquito feeding behaviorDEN virusesExtrinsic incubation periodFever virusMidgut epitheliumBlood feedingFeeding eventsMidgutViral infection dynamicsZika virusAedes aegyptiCourse of infectionEscape barrierAedes albopictusIncubation period