Brief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics
James K, Lisk S, Payne-Cook C, Farishta Z, Farrelly M, Sheikh A, Slusarczyk M, Byford S, Day C, Deighton J, Evans C, Fonagy P, Saunders D, Sclare I, Shearer J, Stallard P, Weaver T, Yarrum J, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics. Trials 2024, 25: 302. PMID: 38702825, PMCID: PMC11069277, DOI: 10.1186/s13063-024-08116-7.Peer-Reviewed Original ResearchConceptsSchool-based cluster randomised controlled trialWarwick-Edinburgh Mental Wellbeing ScaleCluster randomised controlled trialRandomised controlled trialsSchools TrialEducational workshopsMental Wellbeing ScaleControlled trialsOutcome data collectionSymptoms of depressionEthnic minority groupsSecondary schoolsReduce stigmaBaseline characteristicsPost-randomisationWellbeing ScaleSelf-referralSelf-referredLower wellbeingStudentsDistressed studentsEthnically diverse sampleSchoolWorkshop programmeGeneral wellbeingClinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK
Bennett S, Cross J, Chowdhury K, Ford T, Heyman I, Coughtrey A, Dalrymple E, Byford S, Chorpita B, Fonagy P, Moss-Morris R, Reilly C, Smith J, Stephenson T, Varadkar S, Blackstone J, Quartly H, Hughes T, Lewins A, Moore E, Walji F, Welch A, Whelan E, Zacharia A, D'Oelsnitz A, Shah M, Xu L, Vezyroglou A, Mitchell K, Nizza I, Ganguli P, Shafran R. Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK. The Lancet 2024, 403: 1254-1266. PMID: 38461840, DOI: 10.1016/s0140-6736(23)02791-5.Peer-Reviewed Original ResearchConceptsChronic health conditionsMental health disordersUsual careMental health interventionsMental health difficultiesHealth conditionsHealth disordersHealth interventionsHealth difficultiesProgramme Grants for Applied Research programmeNational Institute for Health Research Programme Grants for Applied Research programmeTreating common mental health conditionsMICE groupPrimary mental health disorderYoung peopleMental health comorbiditiesMonths post-randomisationStudy inclusionMental health conditionsEvidence-based psychological treatmentsMental health treatmentMental health assessmentIntellectual disabilityParent-reported StrengthsParticipants aged 3Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression
Lisk S, James K, Shearer J, Byford S, Stallard P, Deighton J, Saunders D, Yarrum J, Fonagy P, Weaver T, Sclare I, Day C, Evans C, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression. BMJ Mental Health 2024, 27: e301192. PMID: 39209761, PMCID: PMC11367360, DOI: 10.1136/bmjment-2024-301192.Peer-Reviewed Original ResearchConceptsTreatment-as-usualCluster randomised controlled trialNational Health ServiceElevated symptoms of depressionQuality-adjusted life yearsElevated depressive symptomsSymptoms of depressionRandomised controlled trialsDepressive symptomsSchools TrialElevated symptomsEducational workshopsIntention-to-treatSecondary analysisPersonal Social Services perspectiveControlled trialsMultilevel linear regressionSocial Services perspectiveSchool-based interventionsCost-effectiveIntention-to-treat analysisOutcomes of participantsHealth servicesIncremental cost-effectiveness ratioClinically meaningful effect