A machine-learning approach for differentiating borderline personality disorder from community participants with brain-wide functional connectivity
Lahnakoski J, Nolte T, Solway A, Vilares I, Hula A, Feigenbaum J, Lohrenz T, King-Casas B, Fonagy P, Montague P, Schilbach L. A machine-learning approach for differentiating borderline personality disorder from community participants with brain-wide functional connectivity. Journal Of Affective Disorders 2024, 360: 345-353. PMID: 38806064, DOI: 10.1016/j.jad.2024.05.125.Peer-Reviewed Original ResearchBorderline personality disorderPrediction of borderline personality disorderFunctional connectivityPersonality disorderBorderline personality disorder patientsBorderline personality disorder statusBrain-wide functional connectivityBiomarkers of psychiatric disordersFunctional connectivity markersFunctional connectivity patternsSelf-reported resultsClinical interviewPsychiatric disordersSomatomotor regionsChance levelSeed ROIConnectivity markersComparison correctionSeed regionConnectivity patternsDiscrimination performanceConnectivity valuesDisordersBorderlineGeneralizabilityThe mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders.
Yirmiya K, Constantinou M, Simes E, Bateman A, Wason J, Yakeley J, McMurran M, Crawford M, Frater A, Moran P, Barrett B, Cameron A, Hoare Z, Allison E, Pilling S, Butler S, Fonagy P. The mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders. Psychological Medicine 2024, 54: 2492-2503. PMID: 38563288, DOI: 10.1017/s003329172400062x.Peer-Reviewed Original ResearchConduct disorderPsychopathological factorsMentalization-based treatmentStructure of psychopathologyChildhood conduct disorderAdult male offendersOne-factor modelConfirmatory factor analysisPsychopathological dimensionsTransdiagnostic approachDiverse psychopathologiesBifactor modelAntisocial behaviorCD symptomsClinical interviewPsychopathological structurePsychopathologyMale offendersAdult aggressionMediation modelDevelopmental trajectoriesIncreased aggressionMental statesReflective functioningAggression