2019
Adaptive Immunity: Effector Functions, Regulation, and Vaccination
Kavathas P, Krause P, Ruddle N. Adaptive Immunity: Effector Functions, Regulation, and Vaccination. 2019, 75-95. DOI: 10.1007/978-3-030-25553-4_5.ChaptersAntigen-presenting cellsT cellsB cellsImmune responseInnate cellsEffector cellsInnate antigen-presenting cellsCD4 T helper cellsEffector T cellsB memory cellsT helper cellsSecondary lymphoid organsNaive T cellsBalanced immune responsePathogen-infected host cellsCD4 subsetCytokine milieuHelper cellsLymphoid organsEffector TPlasma cellsEffector functionsAdaptive immuneTypes of pathogensMacrophage responseAdaptive Immunity: Antigen Recognition by T and B Lymphocytes
Kavathas P, Krause P, Ruddle N. Adaptive Immunity: Antigen Recognition by T and B Lymphocytes. 2019, 55-74. DOI: 10.1007/978-3-030-25553-4_4.ChaptersB cell receptorCell receptorMajor histocompatibility complexB lymphocytesKiller T cellsEffective immune responseVariety of antigensT cell receptors (TCRs) bindCentral toleranceT cellsImmune responseHLA proteinsAntigen recognitionHistocompatibility complexIntracellular pathogensCell surfaceReceptorsHLALymphocytesCorresponding antibodiesHost cellsAntibodiesIsotypesMHC systemDefense mechanisms
2012
Cellular basis for clearance of the protozoan parasite Babesia microti in immunocompromised hosts (43.13)
Vannier E, Silver Z, Wilson C, Su J, Chiam J, Laurie S, Telford S, Gelfand J, Krause P, Wortis H. Cellular basis for clearance of the protozoan parasite Babesia microti in immunocompromised hosts (43.13). The Journal Of Immunology 2012, 188: 43.13-43.13. DOI: 10.4049/jimmunol.188.supp.43.13.Peer-Reviewed Original ResearchCD4-/- miceB cellsT cellsMild flu-like illnessBabesia microtiResolution of parasitemiaAbsence of CD4Flu-like illnessRag1-/- miceRole of complementB-cell lymphomaCourse of infectionPrimary etiologic agentMature B cellsCD4-CD8Specific IgGAnti-CD20Athymic miceCell lymphomaFc receptorsHealthy individualsCD4ParasitemiaEtiologic agentInfectious diseases