2015
Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences
Diuk-Wasser MA, Vannier E, Krause PJ. Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences. Trends In Parasitology 2015, 32: 30-42. PMID: 26613664, PMCID: PMC4713283, DOI: 10.1016/j.pt.2015.09.008.Peer-Reviewed Original ResearchConceptsB. microtiDisease severityGreater disease severityEnzootic cycleCoinfected individualsTick-borne pathogenClinical consequencesTherapeutic strategiesLyme diseaseBabesia microtiHost factorsCoinfectionBorrelia burgdorferiB. burgdorferiIxodes ticksMicrotiReservoir hostsSeverityHuman pathogensBurgdorferiApheresis for babesiosis: Therapeutic parasite reduction or removal of harmful toxins or both?
Saifee NH, Krause PJ, Wu Y. Apheresis for babesiosis: Therapeutic parasite reduction or removal of harmful toxins or both? Journal Of Clinical Apheresis 2015, 31: 454-458. PMID: 26481763, DOI: 10.1002/jca.21429.Peer-Reviewed Original ResearchConceptsExchange transfusionHigh-risk populationLife-threatening illnessApparent therapeutic benefitBlood transfusionModerate diseaseClinical presentationAsymptomatic infectionSevere babesiosisSevere diseaseRisk populationsTherapeutic benefitTransfusionMortality rateIntraerythrocytic protozoan parasiteBabesia infectionDiseaseIxodes ticksProtozoan parasiteBabesiosisInfectionGenus BabesiaMost casesPatientsClindamycin
2006
Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿
Alarcon-Chaidez F, Ryan R, Wikel S, Dardick K, Lawler C, Foppa IM, Tomas P, Cushman A, Hsieh A, Spielman A, Bouchard KR, Dias F, Aslanzadeh J, Krause PJ. Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿. MSphere 2006, 13: 1217-1222. PMID: 16928887, PMCID: PMC1656538, DOI: 10.1128/cvi.00201-06.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayImmune responseTick exposureBALB/c miceC3H/HeNTick-borne infectionsHuman granulocytic anaplasmosisDetection of antibodiesLaboratory markersAntibody responseC miceTick biteSalivary proteinsObjective evidenceLyme diseaseImmunosorbent assayGranulocytic anaplasmosisHuman babesiosisSalivary glandsIxodes ticksAntibodiesBlood mealSame assayMiceSerum
2000
Babesiosis
Krause P. Babesiosis. Seminars In Pediatric Infectious Diseases 2000, 11: 182-188. DOI: 10.1053/pi.2000.6229.Peer-Reviewed Original ResearchCombination of clindamycinHuman immunodeficiency virusTypical clinical symptomsPeripheral blood smearDefinitive laboratory diagnosisClinical symptomsImmunodeficiency virusAsymptomatic infectionClinical spectrumSerological evaluationCurrent treatmentSevere diseaseLaboratory diagnosisSporadic casesBlood smearsIntraerythrocytic protozoaLyme diseaseDiseaseEndemic diseaseZoonotic diseaseCausative agentSerious episodesIxodes ticksBabesiosisAdults