2017
Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy
Lu AJ, Syed JS, Nguyen KA, Nawaf CB, Rosoff J, Spektor M, Levi A, Humphrey PA, Weinreb JC, Schulam PG, Sprenkle PC. Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy. Urology 2017, 105: 118-122. PMID: 28322902, DOI: 10.1016/j.urology.2017.01.048.Peer-Reviewed Original ResearchConceptsMultiparametric magnetic resonance imagingSignificant prostate cancerProstate cancerNegative predictive valueMagnetic resonance imagingSystematic TRUSNegative mpMRIProstate biopsyNegative multiparametric magnetic resonance imagingPredictive valueResonance imagingClinically Significant Prostate CancerDynamic contrast enhancement sequencesTemplate mapping biopsyPrior negative biopsySystematic prostate biopsyOverall cancer detectionProstate-specific antigenTemplate prostate biopsyProstate cancer detectionDiffusion-weighted imagingCancer detectionBiopsy naïveMapping biopsyProstate volume
1998
Clinical and pathologic tumor characteristics of prostate cancer as a function of the number of biopsy cores: a retrospective study
Naughton C, Smith D, Humphrey P, Catalona W, Keetch D. Clinical and pathologic tumor characteristics of prostate cancer as a function of the number of biopsy cores: a retrospective study. Urology 1998, 52: 808-813. PMID: 9801104, DOI: 10.1016/s0090-4295(98)00344-6.Peer-Reviewed Original ResearchConceptsProstate cancerBiopsy coresCore biopsySextant core biopsiesProstate volumeTotal prostate-specific antigen valuesProstate-specific antigen valuesMore biopsy coresMore biopsy sessionsPathologic tumor characteristicsPathologic tumor featuresSix-core biopsyTotal biopsy coresTRUS prostate volumeNegative prostate biopsyClinical prostate cancerMore biopsy samplesProstate cancer detectionPSA densityProspective trialInitial biopsyPathologic characteristicsProstatic volumeSerum tPSATumor characteristicsTHE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER
ORNSTEIN D, SMITH D, HUMPHREY P, CATALONA W. THE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER. Journal Of Urology 1998, 159: 1234-1237.. DOI: 10.1097/00005392-199804000-00043.Peer-Reviewed Original ResearchProstate-specific antigen levelTotal PSA levelsSpecific antigen levelsDetectable prostate cancerSerum prostate-specific antigen levelFree PSA levelsPercent free PSAPSA levelsProstate volumeAcute inflammationAntigen levelsProstate cancerFree PSAFree Serum Prostate Specific Antigen LevelsTotal serum prostate-specific antigen (PSA) levelsTotal prostate-specific antigen levelsFree serum PSA levelsMean percent free PSAPercent free PSA levelsProstate cancer screening programsFree serum PSASerum PSA levelsLarge prostate glandsCancer screening programsInfluence of ageTHE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER
ORNSTEIN D, SMITH D, HUMPHREY P, CATALONA W. THE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER. Journal Of Urology 1998, 159: 1234-1237. PMID: 9507843, DOI: 10.1016/s0022-5347(01)63570-5.Peer-Reviewed Original ResearchConceptsProstate-specific antigen levelTotal PSA levelsSpecific antigen levelsDetectable prostate cancerSerum prostate-specific antigen levelFree PSA levelsPercent free PSAPSA levelsProstate volumeAcute inflammationAntigen levelsProstate cancerFree PSAFree Serum Prostate Specific Antigen LevelsTotal serum prostate-specific antigen (PSA) levelsTotal prostate-specific antigen levelsFree serum PSA levelsMean percent free PSAPercent free PSA levelsProstate cancer screening programsFree serum PSASerum PSA levelsLarge prostate glandsCancer screening programsInfluence of age
1995
Effect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum Prostate Specific Antigen Levels
Nadler R, Humphrey P, Smith D, Catalona W, Ratliff T. Effect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum Prostate Specific Antigen Levels. Journal Of Urology 1995, 154: 407-413. DOI: 10.1016/s0022-5347(01)67064-2.Peer-Reviewed Original ResearchConceptsHigh PSA groupMultiple negative biopsiesSerum PSA concentrationNegative biopsyRectal examinationPSA groupElevated serum prostate-specific antigen concentrationSerum prostate-specific antigen levelSerum prostate-specific antigen (PSA) concentrationElevated serum prostate-specific antigen (PSA) levelPSA concentrationProstate-specific antigen levelProstate-specific antigen concentrationSubclinical prostatic inflammationSuspicious rectal examinationDetectable prostate cancerSpecific antigen levelsDigital rectal examinationSpecific antigen concentrationBenign prostatic hyperplasiaEffects of inflammationProstatic inflammationPSA elevationProstate volumeAntigen levelsEffect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum Prostate Specific Antigen Levels
Nadler R, Humphrey P, Smith D, Catalona W, Ratliff T. Effect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum Prostate Specific Antigen Levels. Journal Of Urology 1995, 154: 407-413.. PMID: 7541857, DOI: 10.1097/00005392-199508000-00023.Peer-Reviewed Original ResearchConceptsHigh PSA groupMultiple negative biopsiesSerum PSA concentrationNegative biopsyProstate volumeRectal examinationPSA groupElevated serum prostate-specific antigen concentrationSerum prostate-specific antigen levelSerum prostate-specific antigen (PSA) concentrationElevated serum prostate-specific antigen (PSA) levelPSA concentrationProstate-specific antigen levelProstate-specific antigen concentrationSubclinical prostatic inflammationSuspicious rectal examinationDetectable prostate cancerSpecific antigen levelsDigital rectal examinationSpecific antigen concentrationBenign prostatic hyperplasiaEffects of inflammationProstatic inflammationPSA elevationAntigen levels