HLA-DR7-Specific monoclonal antibodies and a chimpanzee anti-DR7 serum detect different epitopes on the same molecule
Radka S, Bernard Amos D, Quackenbush L, Cresswell P. HLA-DR7-Specific monoclonal antibodies and a chimpanzee anti-DR7 serum detect different epitopes on the same molecule. Immunogenetics 1984, 19: 63-76. PMID: 6198273, DOI: 10.1007/bf00364476.Peer-Reviewed Original ResearchConceptsClass II moleculesChimpanzee antiserumSame class II moleculesDR7 specificitiesSerologic specificityMonoclonal antibodiesBinding-inhibition studiesCell linesSame serologic specificityAllogeneic epitopesNoncytotoxic antibodiesHLA-DR7IgM antibodiesSpecific monoclonal antibodiesDR moleculesDifferent epitopesAntibodiesEpitopesBeta chainCytotoxic activityHomozygous cell linesAntiserumMembrane preparationsCytotoxicitySpecificity