2011
The Impact of Cocaine Use on Outcomes in HIV-Infected Patients Receiving Buprenorphine/Naloxone
Sullivan LE, Botsko M, Cunningham CO, O'Connor PG, Hersh D, Mitty J, Lum PJ, Schottenfeld RS, Fiellin DA. The Impact of Cocaine Use on Outcomes in HIV-Infected Patients Receiving Buprenorphine/Naloxone. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 56: s54-s61. PMID: 21317595, PMCID: PMC3065971, DOI: 10.1097/qai.0b013e3182097576.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBuprenorphineBuprenorphine, Naloxone Drug CombinationCocaine-Related DisordersFemaleHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsNeedle SharingOpiate Substitution TreatmentOpioid-Related DisordersProspective StudiesRisk FactorsTreatment OutcomeUnsafe SexConceptsBuprenorphine/naloxoneTimes greater likelihoodBaseline cocaine useOpioid useCocaine useHIV RNAAntiretroviral adherenceTreatment outcomesBuprenorphine/naloxone treatmentGreater likelihoodRisk behaviorsConcurrent opioid useLog10 HIV RNAOpioid-dependent HIVSubsequent opioid useHIV treatment outcomesPercent of patientsIllicit opioid useHIV risk behaviorsSubsequent cocaine useCD4 lymphocytesNaloxone treatmentProspective studyPatientsNaloxone
2006
A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care
Sullivan LE, Barry D, Moore BA, Chawarski MC, Tetrault JM, Pantalon MV, O'Connor PG, Schottenfeld RS, Fiellin DA. A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care. Clinical Infectious Diseases 2006, 43: s184-s190. PMID: 17109305, DOI: 10.1086/508182.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, SublingualAdultAntiretroviral Therapy, Highly ActiveBuprenorphineDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPilot ProjectsProbabilityReference ValuesRisk FactorsTreatment OutcomeConceptsHIV clinical careHIV-1 RNA copies/mLBuprenorphine/naloxone treatmentRNA copies/mLCopies/mLOpioid dependenceClinical careOpioid useNaloxone treatmentPhysician managementTreatment retentionHIV type 1 RNA levelsHIV-1 RNA levelsDose of buprenorphinePartial opioid agonistRNA levelsCD4 lymphocyte countBuprenorphine/naloxoneOpioid-dependent patientsUrine toxicology testsWeeks of treatmentHuman immunodeficiency virusUrine test resultsBetter treatment retentionUntreated opioid dependence
2002
Risk for Delirium Tremens in Patients with Alcohol Withdrawal Syndrome1
Fiellin DA, O'Connor PG, Holmboe ES, Horwitz RI. Risk for Delirium Tremens in Patients with Alcohol Withdrawal Syndrome1. Substance Use & Addiction Journal 2002, 23: 83-94. PMID: 12444353, DOI: 10.1080/08897070209511478.Peer-Reviewed Original ResearchConceptsAdverse clinical featuresDelirium tremensComplicated withdrawalBlood pressureAlcohol withdrawalClinical featuresComplicated alcohol withdrawalElevated blood pressureSystolic blood pressureCase-control studyDSM-IV criteriaComorbidity scoreMedical comorbiditiesDetoxification unitEligibility criteriaTremensWithdrawalRiskComorbiditiesPatientsAdmissionHospitalCasesControl
1998
Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment
Durante AJ, Selwyn PA, O'Connor PG. Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment. Addiction 1998, 93: 1393-1401. PMID: 9926545, DOI: 10.1046/j.1360-0443.1998.939139310.x.Peer-Reviewed Original ResearchConceptsMycobacterium tuberculosis infectionTB knowledgeTuberculosis infectionDrug treatment programsRisk factorsDrug usersPositive TB skin testsTreatment programTB skin testTB risk factorsM. tuberculosis infectionTuberculin skin testingLow TB incidenceNeedles/syringesNon-white raceIncidence of infectionDrug treatment facilitiesPrevalence of infectionSubstance abuse treatmentSubsample of clientsPreventive therapyTB controlSkin testingTB incidenceInfected subjects
1997
PHYSICIAN IMPAIRMENT BY SUBSTANCE ABUSE
O'Connor P, Spickard A. PHYSICIAN IMPAIRMENT BY SUBSTANCE ABUSE. Medical Clinics Of North America 1997, 81: 1037-1052. PMID: 9222267, DOI: 10.1016/s0025-7125(05)70562-9.Peer-Reviewed Original ResearchConceptsSubstance abusePhysician impairmentIllicit drug abusePrevalence of alcoholSubstance abuse problemsImpaired physiciansGeneral populationTreatment approachesPrescription drugsPhysiciansDrug abuseAbuse problemsImpairmentMedicolegal standpointCare organizationsPatientsImproved attentionAbuseHospitalPrevalence
1994
HIV infection and cocaine use in methadone maintained and untreated intravenous drug users
Meandzija B, O'Connor P, Fitzgerald B, Rounsaville B, Kosten T. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug And Alcohol Dependence 1994, 36: 109-113. PMID: 7851277, DOI: 10.1016/0376-8716(94)90092-2.Peer-Reviewed Original ResearchConceptsIntravenous drug usersMethadone maintenance treatmentMethadone maintenance programHIV infectionCocaine useMore cocaine useMaintenance treatmentRisk factorsDrug usersMethadone maintenance treatment groupHuman immunodeficiency virus (HIV) transmissionAfrican AmericansMaintenance treatment groupNon-infected subjectsInjection frequencyHIV-negativeHIV testingDrug injectionStratified analysisTreatment groupsTotal cocaineHIVRisk behaviorsGreater riskInfection
1989
Primary medical care for IVDU's: a model for future care.
Schottenfeld RS, O'Connor PG. Primary medical care for IVDU's: a model for future care. NIDA Research Monograph 1989, 95: 403-4. PMID: 2641009.Peer-Reviewed Original Research