2008
Long‐Term Treatment with Buprenorphine/Naloxone in Primary Care: Results at 2–5 Years
Fiellin DA, Moore BA, Sullivan LE, Becker WC, Pantalon MV, Chawarski MC, Barry DT, O'Connor PG, Schottenfeld RS. Long‐Term Treatment with Buprenorphine/Naloxone in Primary Care: Results at 2–5 Years. American Journal On Addictions 2008, 17: 116-120. PMID: 18393054, DOI: 10.1080/10550490701860971.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCombined Modality TherapyCounselingCross-Sectional StudiesDose-Response Relationship, DrugDrug Administration ScheduleDrug Therapy, CombinationFemaleFollow-Up StudiesHeroin DependenceHumansLong-Term CareMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPatient DropoutsPrimary Health CareSubstance Abuse DetectionTreatment OutcomeConceptsOpioid-dependent patientsAdverse eventsSerum transaminasesBuprenorphine/naloxone treatmentSerious adverse eventsBuprenorphine/naloxoneLong-term outcomesOffice-based treatmentIllicit drug useOpioid useClinical stabilityNaloxone treatmentPrimary outcomePatient satisfactionPrimary careTerm treatmentDrug useUrine samplesPatientsTreatmentTransaminaseOutcomesYearsModerate levelsPercent
2002
A Staging System to Predict Prognosis among Methadone Maintenance Patients, Based on Admission Characteristics
Favrat B, Rao S, O'Connor PG, Schottenfeld R. A Staging System to Predict Prognosis among Methadone Maintenance Patients, Based on Admission Characteristics. Substance Use & Addiction Journal 2002, 23: 233-244. PMID: 12438836, DOI: 10.1080/08897070209511496.Peer-Reviewed Original ResearchConceptsStaging systemAdverse dischargeOpioid maintenance therapyU.S. general internistsMethadone maintenance patientsMethadone maintenance treatmentMain outcome measuresMethadone maintenance programProportional hazards modelIllicit drug useHistory of diseaseOutset of treatmentPrevious prison termsMaintenance therapyConsecutive patientsEntire cohortMaintenance patientsMaintenance treatmentAdmission characteristicsOutcome measuresGeneral internistsPrognostic studiesStage IIIPatientsStage IA Staging System to Predict Prognosis Among Methadone Maintenance Patients, Based on Admission Characteristics
Favrat B, Rao S, O'Connor P, Schottenfeld R. A Staging System to Predict Prognosis Among Methadone Maintenance Patients, Based on Admission Characteristics. Substance Use & Addiction Journal 2002, 23: 233-244. DOI: 10.1023/a:1021150217215.Peer-Reviewed Original ResearchStaging systemAdverse dischargeOpioid maintenance therapyU.S. general internistsMethadone maintenance patientsMethadone maintenance treatmentMain outcome measuresMethadone maintenance programProportional hazards modelIllicit drug useHistory of diseaseOutset of treatmentPrevious prison termsMaintenance therapyConsecutive patientsEntire cohortMaintenance patientsMaintenance treatmentAdmission characteristicsOutcome measuresGeneral internistsPrognostic studiesStage IIIPatientsStage I
2001
Methadone Maintenance in Primary Care: A Randomized Controlled Trial
Fiellin DA, O'Connor PG, Chawarski M, Pakes JP, Pantalon MV, Schottenfeld RS. Methadone Maintenance in Primary Care: A Randomized Controlled Trial. JAMA 2001, 286: 1724-1731. PMID: 11594897, DOI: 10.1001/jama.286.14.1724.Peer-Reviewed Original ResearchConceptsOpioid-dependent patientsNarcotic treatment programsOffice-based careStable opioid-dependent patientsIllicit drug usePrimary care physiciansMethadone maintenanceUse of healthDrug useNTP patientsCare physiciansClinical instabilityFunctional statusPrimary care physician's officeMethadone maintenance therapyPrimary care internistsMethadone maintenance patientsOpen clinical trialIllicit opiate useToxicology test resultsQuality of careMaintenance therapyUsual careControlled TrialsOpioid dependence
2000
Thrice-weekly versus daily buprenorphine maintenance
Schottenfeld R, Pakes J, O’Connor P, Chawarski M, Oliveto A, Kosten T. Thrice-weekly versus daily buprenorphine maintenance. Biological Psychiatry 2000, 47: 1072-1079. PMID: 10862807, DOI: 10.1016/s0006-3223(99)00270-x.Peer-Reviewed Original ResearchConceptsSublingual buprenorphineMaintenance treatmentSelf-reported illicit drug useDrug useOpioid agonist maintenance treatmentOpioid-positive urine testsAgonist maintenance treatmentDaily clinic attendanceDaily sublingual buprenorphineThrice-weekly dosingOpioid-dependent patientsUrine toxicology testsSignificant differencesIllicit drug useSelf-reported numberBuprenorphine maintenanceClinic attendanceWeekly doseIllicit opioidsMedication complianceThrice weeklyUrine testsOutcome measuresBuprenorphineCounseling attendance