2006
Major erythrocyte membrane protein genes in EKLF-deficient mice
Nilson DG, Sabatino DE, Bodine DM, Gallagher PG. Major erythrocyte membrane protein genes in EKLF-deficient mice. Experimental Hematology 2006, 34: 705-712. PMID: 16728274, DOI: 10.1016/j.exphem.2006.02.018.Peer-Reviewed Original ResearchConceptsErythrocyte membrane protein genesMembrane protein geneWild-type backgroundBand 3 geneProtein geneErythroid Krüppel-like factorGamma-globinGamma-globin mRNA levelsLevel of transcriptionGamma-globin expressionFull transcriptional activityKrüppel-like factorBeta-spectrin geneBand 3 mRNAGamma-globin mRNABeta-globin geneSteady-state mRNA levelsEmbryonic lethalityMRNA levelsEKLFAnkyrin promoterMembrane genesTranscriptional activityGlobin chain imbalanceErythroid cells
2005
Genetic Evidence That an 11 Amino Acid β-Hairpin Loop in the Cytoplasmic Domain of Band 3 Is Responsible for at Least 50% of Ankyrin Binding in Mouse Erythrocytes.
Markham N, Parry E, Stefanovic M, Gallagher P, Low P, Bodine D. Genetic Evidence That an 11 Amino Acid β-Hairpin Loop in the Cytoplasmic Domain of Band 3 Is Responsible for at Least 50% of Ankyrin Binding in Mouse Erythrocytes. Blood 2005, 106: 1659. DOI: 10.1182/blood.v106.11.1659.1659.Peer-Reviewed Original ResearchΒ-hairpin loopCytoplasmic domainWild typeHuman band 3Neomycin resistance geneMembrane proteinsBand 3Mutant allelesBand 3 cytoplasmic domainResistance genesLevels of mRNARed cell membrane proteinsIntegral erythrocyte membrane proteinsSpectrin-actin cytoskeletonCre recombinase proteinDomain 3Embryonic stem cellsQuantitative RT-PCR analysisCell membrane proteinsNormal Mendelian ratioBand 3 mRNATransgenic miceAnion exchange proteinMutant erythrocytesBand 3 gene