Featured Publications
Systemic Racism as a Determinant of Health Inequities for People With Substance Use Disorder
Jegede O, Bellamy C, Jordan A. Systemic Racism as a Determinant of Health Inequities for People With Substance Use Disorder. JAMA Psychiatry 2024, 81: 225-226. PMID: 38231489, DOI: 10.1001/jamapsychiatry.2023.4958.Peer-Reviewed Original ResearchAccess challenges to opioid use disorder treatment among individuals experiencing homelessness: Voices from the streets
Hsu M, Jung O, Kwan L, Jegede O, Martin B, Malhotra A, Suzuki J. Access challenges to opioid use disorder treatment among individuals experiencing homelessness: Voices from the streets. Journal Of Substance Use And Addiction Treatment 2023, 157: 209216. PMID: 37981243, DOI: 10.1016/j.josat.2023.209216.Peer-Reviewed Original ResearchOpioid use disorderSocioeconomic statusUse disordersCOVID-19 pandemicBuprenorphine/naloxoneActive substance useUse disorder treatmentPercent of participantsActive prescriptionMOUD accessSublingual buprenorphineOUD treatmentTreatment gapTreatment accessMOUDDisorder treatmentBuprenorphineAdverse effectsSubstance useVulnerable populationsIndividual-level factorsMedicationsAccess challengesWhite participantsDisordersCorrelates of Perceived Discrimination Related to Substance Use Disorders Among Patients in Methadone Maintenance Treatment
Nwanaji-Enwerem U, Beitel M, Oberleitner D, Gazzola M, Eggert K, Oberleitner L, Jegede O, Zheng X, Redeker N, Madden L, Barry D. Correlates of Perceived Discrimination Related to Substance Use Disorders Among Patients in Methadone Maintenance Treatment. Journal Of Psychoactive Drugs 2023, 56: 530-540. PMID: 37399330, PMCID: PMC10761588, DOI: 10.1080/02791072.2023.2230571.Peer-Reviewed Original ResearchMethadone maintenance treatmentSubstance use disordersLogistic regression modelsUse disordersMaintenance treatmentTreatment-related characteristicsOpioid use disorderFinal logistic regression modelBSI-18 depressionAge of onsetRegression modelsMMT programDepressive symptomsMeasures of demographicsPatientsBivariate analysisSubstance abuseSignificant correlatesDisordersCorrelatesMedian splitAgeParticipantsTreatmentLikert-type scaleThe Current Status of Medical Student Education on Opioids
Jegede O, Na P, Petrakis I, Muvvala S. The Current Status of Medical Student Education on Opioids. 2023, 121-138. DOI: 10.1093/oxfordhb/9780197618431.013.5.Peer-Reviewed Original ResearchMultimorbidity and Correlates of Comorbid Depression and Generalized Anxiety Disorder in a Nationally Representative US Sample
Jegede O, Stefanovics E, Rhee T, Rosenheck R. Multimorbidity and Correlates of Comorbid Depression and Generalized Anxiety Disorder in a Nationally Representative US Sample. The Journal Of Nervous And Mental Disease 2023, 211: 355-361. PMID: 36807207, DOI: 10.1097/nmd.0000000000001625.Peer-Reviewed Original ResearchConceptsMajor depressive disorderAdditional psychiatric diagnosesRepresentative US sampleComorbid groupPsychiatric disordersPsychiatric diagnosisPoor mental health qualityMental health-related qualityPoorer mental health-related qualityAnxiety disordersHealth-related qualityAdditional psychiatric disordersNationally Representative US SampleMental health qualityLogistic regression analysisSubstance use disordersNational Epidemiologic SurveyMDD-only groupRelated Conditions-IIISingle disorder groupsGeneralized anxiety disorderSingle diagnosis groupsPsychiatric comorbidityComorbid depressionDepressive disorderAssociative Stigma Among Community Mental Health Professionals in Work and Nonwork Settings
Jegede O, Matsuura T, Rosenheck R. Associative Stigma Among Community Mental Health Professionals in Work and Nonwork Settings. Stigma And Health 2024 DOI: 10.1037/sah0000529.Peer-Reviewed Original ResearchAssociated stigmaCommunity mental health professionalsCommunity mental health centerUrban community mental health centerMental health stigmaNational sampleTotal scoreMental health centerMental health cliniciansMental health professionalsNonwork settingsHealth stigmaStigma ScaleAdequate internal consistencyAS total scoreHealth professionalsHealth cliniciansWork settingsHealth centersMental illnessInternal consistencyStigmaCliniciansSocial ostracismScoresThe Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review
Jegede O, De Aquino J, Hsaio C, Caldwell E, Funaro M, Petrakis I, Muvvala S. The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review. Journal Of Addiction Medicine 2024, 18: 499-510. PMID: 39356620, PMCID: PMC11449257, DOI: 10.1097/adm.0000000000001356.Peer-Reviewed Original ResearchNonmedical opioid useOpioid use disorderOpioid useWithdrawal symptomsTreatment outcomesSymptoms prior to treatmentUse disorderRisk of precipitated withdrawalLow-dose buprenorphineSynthetic opioidsPotency synthetic opioidsConclusions Current evidencePrecipitated withdrawalRisk of overdoseDosing strategiesPharmacological interactionsClinical significanceDecreased riskWeb of ScienceOpioidInclusion criteriaCurrent evidenceClinical implicationsMOUDPainIntegrating Ambulatory Addiction Consultation Service Into a Community Mental Health Center
Jegede O, Muvvala S, Cahill J, Wade R, Jordan A. Integrating Ambulatory Addiction Consultation Service Into a Community Mental Health Center. Journal Of Addiction Medicine 2022, 17: 126-128. PMID: 36111994, DOI: 10.1097/adm.0000000000001081.Peer-Reviewed Original ResearchConceptsCommunity mental health centerAddiction consult serviceMental health centersHealth centersConsult serviceConsultation serviceModel of careEvidence-based treatmentsAcute settingAmbulatory settingAddiction treatmentCareAmbulatory systemDrugsAddiction professionalsTreatmentPatientsReplicable modelSettingPsychiatric and Substance Use Disorders and Related Service Use in the Diverse Black Sub-Populations in the United States
Jegede O, Na PJ, Rhee TG, Stefanovics EA, Rosenheck RA. Psychiatric and Substance Use Disorders and Related Service Use in the Diverse Black Sub-Populations in the United States. Journal Of Racial And Ethnic Health Disparities 2021, 9: 2237-2247. PMID: 34590245, DOI: 10.1007/s40615-021-01163-9.Peer-Reviewed Original ResearchConceptsRelated service useSubstance use diagnosesSubstance use disordersService useUse diagnosesUse disordersRelated Conditions Wave IIILogistic regression analysisNational Epidemiologic SurveyDiverse black populationsAfrican AmericansMultinomial logistic regression analysisBlack/African AmericanBlack populationClinical characteristicsMethodsThe dataWave IIIEpidemiologic SurveyMeasures of qualityMental healthPhysical healthReference groupSubstance useGroup differencesBlack individualsRates and correlates of dual diagnosis among adults with psychiatric and substance use disorders in a nationally representative U.S sample
Jegede O, Rhee TG, Stefanovics EA, Zhou B, Rosenheck RA. Rates and correlates of dual diagnosis among adults with psychiatric and substance use disorders in a nationally representative U.S sample. Psychiatry Research 2022, 315: 114720. PMID: 35834863, DOI: 10.1016/j.psychres.2022.114720.Peer-Reviewed Original ResearchConceptsSubstance use disordersDual diagnosisPsychiatric disordersIndependent correlatesUse disordersDrug use diagnosesService use characteristicsPoor mental HRQOLRelated Conditions Wave IIINational Epidemiologic SurveyRepresentative US sampleMental HRQOLSUD diagnosisUse diagnosesTreatment needsEpidemiologic SurveyWave IIIAdult traumaMedical problemsSuicide attemptsDiagnosisDisordersAdultsFurther studiesSocial support
2024
Addressing Racial and Ethnic Inequities in Opioid Overdose Mortality: Strategies for Equitable Interventions and Structural Change
Cruz F, Jegede O. Addressing Racial and Ethnic Inequities in Opioid Overdose Mortality: Strategies for Equitable Interventions and Structural Change. Current Psychiatry Reports 2024, 1-7. PMID: 39496984, DOI: 10.1007/s11920-024-01556-7.Peer-Reviewed Original ResearchOpioid overdose mortalityOverdose mortalityAdaptation of evidence-based interventionsSocial determinants of healthCultural adaptation of evidence-based interventionsEthnic inequalitiesDeterminants of healthEvidence-based interventionsHarm reduction servicesSubstance use disorder preventionSocial determinantsTailored interventionsEquitable interventionsEquity-based frameworkOpioid use disorderReduction servicesSubstance use outcomesAnti-racism praxisCultural adaptationStructural competencyStructural racismDisorder preventionPolicy-levelInterventionUse disorderAssociations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review
Hsaio C, DiMeola K, Jegede O, Funaro M, Langstengel J, Yaggi H, Barry D. Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review. Current Addiction Reports 2024, 1-17. DOI: 10.1007/s40429-024-00606-7.Peer-Reviewed Original ResearchOpioid use disorderOUD severityUse disorderTreatment characteristicsOpioid use disorder treatment settingsTreatment of sleepDosing scheduleDisorder severityOpioidPainWeb of ScienceAssessed patientsCochrane LibraryMeasures of sleepMOUD treatmentCurrent evidenceMOUDSleepSleep disturbanceProvider preferencesPatientsStudy examined sleepDisordersTreatment settingsMedicationPersistent distress related to systemic racism among black veterans in the United States
Whealin J, Jegede O, Na P, Haeny A, Pietrzak R. Persistent distress related to systemic racism among black veterans in the United States. Journal Of Affective Disorders 2024, 365: 375-378. PMID: 39147153, DOI: 10.1016/j.jad.2024.08.052.Peer-Reviewed Original ResearchAdverse mental health sequelaeRisk of mental health problemsMilitary veteransIncreased risk of mental health problemsEthnic minority veteransSystemic racismMental health sequelaeMental health problemsUse of self-reportsEthnic minority populationsNationally representative sampleUS military veteransMultinomial logistic regression analysisSignificant emotional burdenStudy periodNon-veteransLogistic regression analysisEmotional burdenMinority veteransBlack veteransUS veteransHealth sequelaeBaseline assessmentHealthcare systemUS populationDisentangling the effects of racism-related stress on opioid use disorder and chronic pain outcomes
Nunes J, Jegede O, De Aquino J. Disentangling the effects of racism-related stress on opioid use disorder and chronic pain outcomes. The American Journal Of Drug And Alcohol Abuse 2024, 50: 455-461. PMID: 39018662, DOI: 10.1080/00952990.2024.2369866.Peer-Reviewed Original ResearchOpioid use disorderUse disorderRacism-related stressChronic pain outcomesOpioid overdose mortality ratesOverdose mortality ratesHealthcare disparitiesBiopsychosocial burdenPain outcomesPrescribed opioidsUndertreated painChronic painPain managementOpioid mortalityPerpetuate stigmaTreat painPain experienceOpioidPainRisk factorsMinoritized populationsMinoritized peopleMortality rateDisparitiesAddiction treatmentWhat Would Equitable Harm Reduction Look Like?
Jegede O, Nunes J, Tumenta T, Black C, DeAquino J. What Would Equitable Harm Reduction Look Like? The AMA Journal Of Ethic 2024, 26: e572-579. PMID: 38958426, DOI: 10.1001/amajethics.2024.572.Peer-Reviewed Original ResearchConceptsDeterminants of health frameworkHarm reductionPerson-centered interventionsReduction programsPromote harm reductionHarm reduction strategiesHarm reduction programsHealth equityHealth frameworkEthnic inequalitiesSocial justiceDrug usePWUDOrganizational policiesMargin ExperimentReduction strategiesHarmCareStigmaProgramHealthRaciallyAntiracistInterventionJusticeInvestigating the association between multiple substance Use and dating violence involvement among U.S adolescents
Nwabueze C, Nkemjika S, Okereke O, Fagbenle O, Arisoyin A, Ibeneme C, Brown C, Ikekwere J, Petion J, Oke O, Johnson B, Azim S, Jegede O. Investigating the association between multiple substance Use and dating violence involvement among U.S adolescents. Psychiatry Research Communications 2024, 4: 100150. DOI: 10.1016/j.psycom.2023.100150.Peer-Reviewed Original ResearchMultiple substance useSubstance useHigher oddsMultiple logistic regressionTimes higher oddsYouth Risk Behavior Surveillance SystemPublic health concernUnited States adolescentsStudy populationNight sleepPast monthLogistic regressionHealth concernPrevalenceConfoundersOddsAdolescentsSurveillance systemMeta-analytic studyAssociationRepresentative sampleViolence involvementMore substancesRepresentative surveyDescriptive analysis
2023
Opioid use disorder amongst young people living with HIV: A 10-year trend
Ikekwere J, Eiger R, Heward B, Longcoy J, Okobi O, Oladunjoye A, Onyeaka H, Kompella S, Jegede O. Opioid use disorder amongst young people living with HIV: A 10-year trend. Psychiatry Research Communications 2023, 3: 100140. DOI: 10.1016/j.psycom.2023.100140.Peer-Reviewed Original ResearchOpioid use disorderMental health diagnosesUse disordersDiagnosis of OUDRisk of OUDNational Inpatient Sample dataMajor public health concernNew HIV diagnosesMultivariable logistic regressionMental health servicesHIV-positive young peoplePublic health concernMental health issuesComorbid HIVHIV diagnosisOpioid useOUD diagnosisEffective treatmentHigh riskHIVPrevention strategiesICD codesTargeted preventionDrug useHealth servicesMonotonic Association of Increasing Past-Year Substance Use Disorder across a Four-Level Trauma Post-Traumatic Stress Disorder (PTSD) Hierarchy in a Nationwide Sample
Jegede O, Manhapra A, Zhou B, Rhee T, Rosenheck R. Monotonic Association of Increasing Past-Year Substance Use Disorder across a Four-Level Trauma Post-Traumatic Stress Disorder (PTSD) Hierarchy in a Nationwide Sample. Journal Of Dual Diagnosis 2023, 19: 231-239. PMID: 37796996, DOI: 10.1080/15504263.2023.2260339.Peer-Reviewed Original ResearchConceptsSubstance use disordersTrauma exposureCurrent PTSDUse disordersComparison of adultPast-year substance use disorderSUD prevalencePTSDRelated Conditions Wave IIINational Epidemiologic SurveyTrauma groupNationwide sampleDifferential effectsGreater likelihoodSUD diagnosisUnadjusted resultsClinical consequencesHierarchical groupsEpidemiologic SurveyWave IIIAdultsDisordersMonotonic associationPrior groupPrevalenceA Review of the Mental Health Sequelae of the SARS-CoV-2 (COVID-19): Preparedness Perspective
Metellus P, Jegede O, Brown C, Qureshi D, Nkemjika S. A Review of the Mental Health Sequelae of the SARS-CoV-2 (COVID-19): Preparedness Perspective. Cureus 2023, 15: e37643. PMID: 37200645, PMCID: PMC10187944, DOI: 10.7759/cureus.37643.Peer-Reviewed Original ResearchChronic use of benzodiazepines: The problem that persists
Louie D, Jegede O, Hermes G. Chronic use of benzodiazepines: The problem that persists. The International Journal Of Psychiatry In Medicine 2023, 58: 426-432. PMID: 36972700, DOI: 10.1177/00912174231166252.Peer-Reviewed Original Research