2013
Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke
Mishra NK, Mandava P, Chen C, Grotta J, Lees KR, Kent TA, collaboration V. Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke. International Journal Of Stroke 2013, 9: 613-617. PMID: 24148895, DOI: 10.1111/ijs.12162.Peer-Reviewed Original ResearchConceptsTissue plasminogen activatorBaseline National InstitutesHealth Stroke ScaleNon-Caucasian patientsPlasminogen activatorStroke ScaleNational InstituteRace-EthnicityNon-thrombolysed patientsStroke III TrialRace-ethnicity groupsNeuroprotection trialsIII trialsDiabetes statusFunctional outcomeImproved outcomesPatientsNeurological disordersCaucasian populationDifferential responseEthnicity groupsOutcomesCaucasiansOddsTrials
2009
Mismatch-Based Delayed Thrombolysis
Mishra NK, Albers GW, Davis SM, Donnan GA, Furlan AJ, Hacke W, Lees KR. Mismatch-Based Delayed Thrombolysis. Stroke 2009, 41: e25-e33. PMID: 19926836, DOI: 10.1161/strokeaha.109.566869.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageIntracerebral hemorrhageFavorable outcomeMismatch patientsSuccessful reperfusionStroke onsetClinical outcomesClinical benefitRecanalization/reperfusionPhase III trialsFavorable clinical outcomeWeb of KnowledgeDelayed thrombolysisMismatch selectionThrombolysis trialsIII trialsRelevant trialsCase seriesRoutine careThrombolytic therapyClinical findingsClinical trialsImproved outcomesOdds ratioPretreatment imaging