2023
Association of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke
Stulberg E, Harris B, Zheutlin A, Delic A, Sheibani N, Anadani M, Yaghi S, Petersen N, de Havenon A. Association of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke. Neurology 2023, 101: e1145-e1157. PMID: 37487742, PMCID: PMC10513881, DOI: 10.1212/wnl.0000000000207599.Peer-Reviewed Original ResearchConceptsAverage real variabilityNonstroke patientsDischarge destinationHospital deathIschemic strokeIll patientsIllness severityWorse outcomesAdult intensive care unit patientsMinimum mean arterial pressureIntensive care unit patientsIntensive Care III databaseBlood pressure goalsAcute ischemic strokeMean arterial pressureBlood pressure variabilityCare unit patientsRisk of deathMedical Information MartUnit patientsArterial pressureIntracerebral hemorrhageSubarachnoid hemorrhageRisk factorsEffect modification
2022
Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002)
Top I, Chen Y, Bartolome D, Rapuano A, Gilmore E, Sheth K, Matouk C, Petersen N, Kim J. Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3539.Peer-Reviewed Original ResearchBlood pressure reductionIschemic changesSubarachnoid hemorrhagePressure reductionHemorrhageNimodipine
2019
Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage. Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.Peer-Reviewed Original ResearchConceptsLimits of autoregulationAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageFunctional outcomeArterial pressureIntracranial pressureBP targetsWorse outcomesPercent timeBlood pressure targetsBlood pressure managementMean arterial pressureModified Rankin ScalePotential neuroprotective strategiesWorse functional outcomePoor functional outcomeCerebral blood flowMultivariate logistic regressionTotal monitoring periodAutoregulatory indexPressure targetsCerebral ischemiaNeuroprotective strategiesRankin ScaleCerebral autoregulationDeviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.Peer-Reviewed Original ResearchChanges on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage
Ortega-Gutierrez S, Samaniego E, Reccius A, Huang A, Zheng-Lin B, Masukar A, Marshall R, Petersen N. Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2019, 127: 149-153. PMID: 31407076, DOI: 10.1007/978-3-030-04615-6_22.Peer-Reviewed Original ResearchConceptsDynamic cerebral autoregulationAneurysmal subarachnoid hemorrhageCerebral blood flow velocityBlood pressureSymptomatic vasospasmCerebral ischemiaSAH patientsCerebral autoregulationSubarachnoid hemorrhageCerebral blood flow regulationGlasgow Coma ScoreSystemic blood pressureDelayed Cerebral IschemiaLarge cohort studyBlood flow regulationBlood flow velocityRecording periodDCA assessmentCohort studyComa ScoreEntire recording periodSymptom onsetMedian timeDay 3Early identificationDynamic Cerebral Autoregulation and Personalized Blood Pressure Monitoring in Patients with Aneurysmal Subarachnoid Hemorrhage (aSAH) (P5.3-025)
Silverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Sheth K, Gilmore E, Petersen N. Dynamic Cerebral Autoregulation and Personalized Blood Pressure Monitoring in Patients with Aneurysmal Subarachnoid Hemorrhage (aSAH) (P5.3-025). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.p5.3-025.Peer-Reviewed Original Research
2012
Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage (P06.257)
Ortega-Gutierrez S, Petersen N, Reccius A, Huang A, Linares-Tapia G, Marshall R, Badjatia N. Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage (P06.257). Neurology 2012, 78: p06.257-p06.257. DOI: 10.1212/wnl.78.1_meetingabstracts.p06.257.Peer-Reviewed Original Research