Mechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study.
Rodriguez-Calienes A, Hassan A, Siegler J, Galecio-Castillo M, Farooqui M, Jumaa M, Janjua N, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Nguyen T, Sheth S, Yoo A, Linares G, Lu Y, Vivanco-Suarez J, Ortega-Gutierrez S. Mechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study. Interventional Neuroradiology 2023, 15910199231196960. PMID: 37642978, DOI: 10.1177/15910199231196960.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageNIH Stroke ScaleMechanical thrombectomyHospital mortalityComplete reperfusionTandem lesionsFunctional independenceAnterior circulation tandem lesionsEffectiveness of MTMulticenter cohort studyLarge vessel occlusionFuture prospective studiesTreatment of patientsOutcomes of interestMulticenter registryStroke ScaleCohort studyIntracranial hemorrhageProspective studyVessel occlusionHematoma 2Treatment weightingPatientsInverse probabilityMortalitySafety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions
Rodriguez-Calienes A, Galecio-Castillo M, Farooqui M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Alhajala H, Ikram A, Rizzo F, Qureshi A, Begunova L, Matsoukas S, Vigilante N, Salazar-Marioni S, Abdalkader M, Gordon W, Soomro J, Turabova C, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Sheth S, Ortega-Gutierrez S. Safety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions. Stroke 2023, 54: 2522-2533. PMID: 37602387, PMCID: PMC10599264, DOI: 10.1161/strokeaha.123.042966.Peer-Reviewed Original ResearchConceptsRisk of sICHParenchymal hematoma type 2Symptomatic intracranial hemorrhageRankin Scale score 0Intravenous antiplatelet therapyIntravenous thrombolysisFavorable functional outcomeMechanical thrombectomyHemorrhagic transformationFunctional outcomeType 2Antiplatelet therapyHospital mortalitySuccessful reperfusionComplete reperfusionScore 0Tandem lesionsAnterior circulation tandem lesionsExcellent functional outcomeIVT treatmentStroke centersMulticenter cohortPrimary outcomeRevascularization techniquesAlone group