2014
Concussive brain injury from explosive blast
de Lanerolle NC, Hamid H, Kulas J, Pan JW, Czlapinski R, Rinaldi A, Ling G, Bandak FA, Hetherington HP. Concussive brain injury from explosive blast. Annals Of Clinical And Translational Neurology 2014, 1: 692-702. PMID: 25493283, PMCID: PMC4241796, DOI: 10.1002/acn3.98.Peer-Reviewed Original ResearchMild traumatic brain injuryBlast mild traumatic brain injuryPosttraumatic stress disorderMagnetic resonance spectroscopic imagingN-acetyl aspartateBrain injuryMemory impairmentNAA/ChConcussive brain injuryNAA/CrTraumatic brain injuryVariety of symptomsStudy of veteransLarge animal modelHippocampal injuryNeuronal injuryNeuropsychiatric deficitsRight hippocampusMTBI subjectsPosterior hippocampusAnimal modelsHippocampusInjuryStress disorderCognitive Assessment
2010
Astrocytes and Epilepsy
de Lanerolle NC, Lee TS, Spencer DD. Astrocytes and Epilepsy. Neurotherapeutics 2010, 7: 424-438. PMID: 20880506, PMCID: PMC5084304, DOI: 10.1016/j.nurt.2010.08.002.Peer-Reviewed Original ResearchConceptsSeizure focusReactive astrocytesCausation of seizuresGlial fibrillary acidic proteinHippocampal seizure focusRole of astrocytesTemporal lobe epilepsyFibrillary acidic proteinPositive reactive astrocytesNonsclerotic hippocampiHippocampal sclerosisSclerotic hippocampusSubicular neuronsLobe epilepsyEpileptiform activityInflammatory functionsAstrocytesAction potentialsAcidic proteinPotassium ion channelsVascular interfaceEpilepsyHippocampusPrecise roleHuman brain