Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain
Nishtala SN, Mnatsakanyan N, Pandhare A, Leung C, Jansen M. Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain. Journal Of Neurochemistry 2016, 137: 528-538. PMID: 26875553, PMCID: PMC4860158, DOI: 10.1111/jnc.13578.Peer-Reviewed Original ResearchConceptsGloeobacter violaceus ligand-gated ion channelPentameric ligand-gated ion channelsLigand-gated ion channelsRIC-3Intracellular domainIon channelsType 3 proteinChaperone protein RIC-3Non-excitable cellsWild-type channelsTransmembrane domainProtein factorsHomologous subunitsPentameric assemblyHeteromeric pentamersChimera consistingInteraction surfaceProteinDirect interactionLaevis oocytesProtein expressionFirst experimental evidenceSpecific interactionsSurface expressionFunctional maturation