2011
Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein
Akirav EM, Xu Y, Ruddle NH. Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein. Journal Of Neuroimmunology 2011, 235: 33-39. PMID: 21550671, PMCID: PMC3157307, DOI: 10.1016/j.jneuroim.2011.03.013.Peer-Reviewed Original ResearchConceptsB cellsB cell-deficient μMT miceMyelin oligodendrocyte glycoproteinResident B cellsThymic B cellsCortico-medullary junctionMinor cell populationProduction of LTInsulin mRNA expressionΜMT miceEpithelial cell numberOligodendrocyte glycoproteinThymic expressionAntigen expressionMRNA expressionNormal tissuesCell populationsCell numberCellsExpressionLtUnexpected roleBiological roleLymphotoxinMice
1987
Lymphotoxin: Cloning, Regulation and Mechanism of Killing
Ruddle N, Li C, Tang W, Gray P, McGrath K. Lymphotoxin: Cloning, Regulation and Mechanism of Killing. Novartis Foundation Symposia 1987, 131: 64-87. PMID: 3502460, DOI: 10.1002/9780470513521.ch6.Peer-Reviewed Original ResearchConceptsCDNA libraryBamHI fragmentMurine genomic libraryFull-length cDNACOS-1 cellsCell linesT cell linesNorthern blot analysisGenomic libraryMechanism of killingCDNA probeDNA fragmentationChromosome 17T cell receptorRNABlot analysisCDNAGenesCell receptorCell clonesCellsTarget cellsFragmentsMRNA expressionCloning