2013
Clinical applications of oxymorphone.
Vadivelu N, Maria M, Jolly S, Rosenbloom J, Prasad A, Kaye AD. Clinical applications of oxymorphone. Journal Of Opioid Management 2013, 9: 439-52. PMID: 24481932, DOI: 10.5055/jom.2013.0186.Peer-Reviewed Original ResearchConceptsNew oral preparationNew oral formulationSemisynthetic opioid analgesicSpecific side effectsSevere painOpioid analgesicsParenteral formClinical indicationsOral preparationsStudy populationPharmacological considerationsOral formulationSide effectsPatient needsUS FoodDrug AdministrationHealthcare providersParenteral formulationsClinical applicationPainImportant drugsOxymorphoneAdditional optionPyridomorphinansSpecific considerations
2011
Peripheral opioid receptor agonists for analgesia: a comprehensive review.
Vadivelu N, Mitra S, Hines RL. Peripheral opioid receptor agonists for analgesia: a comprehensive review. Journal Of Opioid Management 2011, 7: 55-68. PMID: 21434585, DOI: 10.5055/jom.2011.0049.Peer-Reviewed Original ResearchConceptsPeripheral opioid receptorsOpioid receptor agonistsOpioid receptorsReceptor agonistOpioid analgesiaPeripheral opioid receptor agonistDelta-opioid receptor agonistPhase I clinical trialPeripheral opioid agonistPeripheral opioid analgesiaDorsal root gangliaObvious theoretical advantagesOpioid agonist activityPeripheral muAfferent nervesAfferent neuronsOpioid analgesicsPeripheral terminalsCentral actionOpioid agonistsAntidiarrheal drugsOpioidergic systemRoot gangliaClinical trialsPeripheral tissues
2010
Buprenorphine: intravenous neuraxial and transdermal applications
Vadivelu N. Buprenorphine: intravenous neuraxial and transdermal applications. 2010, 157-160. DOI: 10.1017/cbo9780511841378.035.ChaptersPain managementAvailable pain medicationsAdjuvant medicationsNeuraxial opioidsPain medicationPain reliefAdverse eventsOpioid analgesicsPain processingMuscle relaxantsPharmacologic principlesNMDA antagonistsLocal anestheticsAnalgesicsCommon dosesClinical settingClinical useParticular drugTransdermal applicationMedicationsCliniciansDrugsAnalgesiaContraindicationsOpioids