2014
Intrathecal drug delivery for chronic pain management-scope, limitations and future
Czernicki M, Sinovich G, Mihaylov I, Nejad B, Kunnumpurath S, Kodumudi G, Vadivelu N. Intrathecal drug delivery for chronic pain management-scope, limitations and future. Journal Of Clinical Monitoring And Computing 2014, 29: 241-249. PMID: 25173564, DOI: 10.1007/s10877-014-9607-1.Peer-Reviewed Original ResearchConceptsIntrathecal drug delivery systemsChronic painOptimal medical managementIntrathecal drug deliveryDifferent implantation techniquesLicensing of drugsSevere morbidityMedical managementMuscle spasmMain indicationsIntrathecal useInvasive techniquesOutcome studiesPainAdverse effectsHealthcare practitionersImplantation techniqueTherapyDrug delivery systemsTherapy systemReview articleDelivery systemDate knowledgeMorbiditySpasm
2011
Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current Options
Mitra S, Khandelwal P, Roberts K, Kumar S, Vadivelu N. Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current Options. Pain Practice 2011, 12: 485-496. PMID: 22008277, DOI: 10.1111/j.1533-2500.2011.00513.x.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsLocal anestheticsLaparoscopic cholecystectomyPain reliefTransversus abdominis plane blockCardiovascular adverse effectsPort-site infiltrationIntra-operative periodSingle modality interventionsFavorable pharmacological characteristicsAnti-inflammatory drugsCOX-2 inhibitorsCyclooxygenase-2 inhibitorNSAID/COXTAP blockNoncardiac surgeryPlane blockSafe analgesiaEarly instillationIntraperitoneal instillationPharmacological characteristicsFibrin sealantInstillationCurrent optionsAdverse effects