2022
IncobotulinimtoxinA (Xeomin) for the treatment of adductor laryngeal dystonia: A prospective, open-label clinical trial
Kohli N, Lerner M, Rashty J, Kirke D, Stewart T, Blitzer A. IncobotulinimtoxinA (Xeomin) for the treatment of adductor laryngeal dystonia: A prospective, open-label clinical trial. American Journal Of Otolaryngology 2022, 43: 103613. PMID: 36055061, DOI: 10.1016/j.amjoto.2022.103613.Peer-Reviewed Original ResearchConceptsAdductor spasmodic dysphoniaSpasmodic dysphoniaOpen-label clinical trialProspective open-label trialAdductor laryngeal dystoniaOpen-label trialFirst-line treatmentVoice Handicap Index-10Side effect profileTransient side effectsNormal functionVHI-10 scoresIncobotulinumtoxinA injectionsEffect profileLine treatmentSystemic diseaseTA muscleBotulinum toxinClinical trialsLaryngeal dystoniaNursing womenThyroarytenoid muscleInjection sessionsExclusion criteriaSide effects
2021
Adequate short- and long-term pain control with non-opiate analgesics after microdirect laryngoscopy
Bisarya PK, Jiang R, Chao J, Narwani V, Lerner M, Kohli N. Adequate short- and long-term pain control with non-opiate analgesics after microdirect laryngoscopy. American Journal Of Otolaryngology 2021, 43: 103267. PMID: 34695699, DOI: 10.1016/j.amjoto.2021.103267.Peer-Reviewed Original ResearchConceptsAdequate pain controlUse of opioidsPain controlPost-operative painDaily VAS scoresMicrodirect laryngoscopyOpioid medicationsVAS scoresLong-term pain controlSingle-institution prospective studyNon-opiate analgesiaPostoperative pain managementSufficient pain controlPost-operative analgesiaNon-opiate analgesicsVisual analog scaleLong-term painT-testVocal fold lesionsStudent's t-testOpioid analgesiaMost patientsPain managementAnalog scaleProspective studyCorrelations of Radiographic and Endoscopic Observations in Subglottic Stenosis
Bourdillon AT, Hajek MA, Wride M, Lee M, Lerner M, Kohli N. Correlations of Radiographic and Endoscopic Observations in Subglottic Stenosis. Annals Of Otology Rhinology & Laryngology 2021, 131: 724-729. PMID: 34459264, DOI: 10.1177/00034894211042768.Peer-Reviewed Original ResearchSafety considerations for esophageal dilation by anesthetic type: A systematic review
Lerner MZ, Bourdillon AT, Dai F, Brackett A, Kohli N. Safety considerations for esophageal dilation by anesthetic type: A systematic review. American Journal Of Otolaryngology 2021, 42: 103128. PMID: 34216877, DOI: 10.1016/j.amjoto.2021.103128.Peer-Reviewed Original ResearchConceptsEsophageal dilationOffice-based techniqueSystematic reviewDerSimonian-Laird random-effects modelType of anesthesiaSmall case seriesOffice-based proceduresFull-text studiesUse of stentsRandom-effects modelComprehensive literature searchInverse variance weightingAdverse eventsAnesthetic typeCase seriesIntravenous sedationGeneral anesthesiaHigh morbidityAnesthesia techniquesLocal anesthesiaEmbase databasesExclusion criteriaEquivalent safetyPRISMA guidelinesRare diseaseExtranodal Head and Neck Mantle Cell Lymphoma: Characteristics, Treatment, and Survival
Breen CT, Chao J, Mehra S, Kohli N. Extranodal Head and Neck Mantle Cell Lymphoma: Characteristics, Treatment, and Survival. Annals Of Otology Rhinology & Laryngology 2021, 131: 412-419. PMID: 34137303, DOI: 10.1177/00034894211025171.Peer-Reviewed Original ResearchConceptsMantle cell lymphomaExtranodal mantle cell lymphomaCumulative incidenceOverall survivalCell lymphomaEnd Results 18 registriesStage IV diseaseEarly-stage diseaseCause-specific hazards modelLate-stage diseaseProportion of casesSignificant differencesExtranodal headChemoradiation therapyCommon subsiteDisease characteristicsCommon siteAnatomic sitesPrimary headRadiation therapyCommon treatmentOral cavityHazards modelStage IIIStage IFactors Affecting Posterior Glottic Stenosis Surgery Outcomes: Systematic Review and Meta-analysis
Kremer C, Jiang R, Singh A, Sukys J, Brackett A, Kohli N. Factors Affecting Posterior Glottic Stenosis Surgery Outcomes: Systematic Review and Meta-analysis. Annals Of Otology Rhinology & Laryngology 2021, 130: 1156-1163. PMID: 33641352, DOI: 10.1177/0003489421997278.Peer-Reviewed Original Research
2020
In Response to Telemedicine in Otorhinolaryngology Practice in Developing Nations
Singh AK, Kasle DA, Kohli N. In Response to Telemedicine in Otorhinolaryngology Practice in Developing Nations. The Laryngoscope 2020, 131: e1068-e1068. PMID: 33159464, DOI: 10.1002/lary.29255.Peer-Reviewed Original ResearchSafety and Feasibility of a Novel Esophageal Balloon for Circumferential Cytologic Sampling
Kohli N, Blitzer A, Jahn A, Cho Y, Budrewicz J, Enos K, Strome M. Safety and Feasibility of a Novel Esophageal Balloon for Circumferential Cytologic Sampling. Annals Of Otology Rhinology & Laryngology 2020, 130: 585-590. PMID: 33412926, DOI: 10.1177/0003489420964831.Peer-Reviewed Original ResearchA Review of Telemedicine Applications in Otorhinolaryngology: Considerations During the Coronavirus Disease of 2019 Pandemic
Singh AK, Kasle DA, Jiang R, Sukys J, Savoca EL, Lerner M, Kohli N. A Review of Telemedicine Applications in Otorhinolaryngology: Considerations During the Coronavirus Disease of 2019 Pandemic. The Laryngoscope 2020, 131: 744-759. PMID: 32942340, PMCID: PMC7537247, DOI: 10.1002/lary.29131.Peer-Reviewed Original ResearchA Manufacturer and User Facility Device Experience Analysis of Upper Aerodigestive Endoscopy Contamination: Is Flexible Laryngoscopy Different?
Jiang R, Kasle DA, Alzahrani F, Kohli N, Lerner MZ. A Manufacturer and User Facility Device Experience Analysis of Upper Aerodigestive Endoscopy Contamination: Is Flexible Laryngoscopy Different? The Laryngoscope 2020, 131: 598-605. PMID: 32558941, DOI: 10.1002/lary.28826.Peer-Reviewed Original ResearchApplication of a Modified Endoscopy Face Mask for Flexible Laryngoscopy During the COVID‐19 Pandemic
Narwani V, Kohli N, Lerner MZ. Application of a Modified Endoscopy Face Mask for Flexible Laryngoscopy During the COVID‐19 Pandemic. Otolaryngology 2020, 163: 107-109. PMID: 32423299, DOI: 10.1177/0194599820928977.Peer-Reviewed Original ResearchConceptsUnknown COVID-19 statusFace maskRisk of aerosolizationAerosol-generating proceduresHigh-risk procedureCOVID-19 positivityCOVID-19 statusCOVID-19 pandemicEndoscopy maskOccupational transmissionOutpatient settingPersonal protection equipmentFlexible laryngoscopyOtolaryngologistsCOVID-19PatientsAirborne pathogensAdditional barriersPandemicLaryngoscopyProtection equipmentArmamentariumAdjunctExamining Referral Patterns between Otolaryngology and Gastroenterology: A Window into Potential Inter-Specialty Knowledge Gaps
Haines A, Kohli N, Lerner BA, Lerner MZ. Examining Referral Patterns between Otolaryngology and Gastroenterology: A Window into Potential Inter-Specialty Knowledge Gaps. Annals Of Otology Rhinology & Laryngology 2020, 129: 801-805. PMID: 32249595, DOI: 10.1177/0003489420916215.Peer-Reviewed Original ResearchConceptsFrequent referral reasonsReferral patternsReferral reasonsMedical record data extractionLaryngopharyngeal reflux diseaseRate of referralICD-10 codesInter-specialty communicationReflux diseaseTotal patientsEsophageal pathologyReferral cohortClinical conditionsOropharyngeal pathologyClinical overlapReferralGastroenterologyDysphagiaOtolaryngologyCohortData extractionDiscrepant ratesDiseaseLPRDPathologyBotulinum Toxin for the Treatment of Motor and Phonic Tics: A Case Report
Kohli N, Blitzer A. Botulinum Toxin for the Treatment of Motor and Phonic Tics: A Case Report. Annals Of Otology Rhinology & Laryngology 2020, 129: 625-627. PMID: 31906695, DOI: 10.1177/0003489419898211.Peer-Reviewed Original ResearchConceptsYale Global Tic Severity ScaleTreatment of motorPhonic ticsCase reportTic Severity ScaleFacial mimetic musculatureOnabotulinum toxinFiberoptic visualizationBotulinum toxinThroat clearingTic disordersSeverity ScaleTic severityObjective decreaseMimetic musculaturePatientsTreatmentLevel VExperienced reductionsMusculatureToxinReportGruntingBoNTSeverity
2018
Osteoradionecrosis of the sternoclavicular joint after laryngopharyngeal radiation
Irizarry R, Shatzkes D, Teng S, Kohli N, Har‐El G. Osteoradionecrosis of the sternoclavicular joint after laryngopharyngeal radiation. The Laryngoscope 2018, 129: 865-870. PMID: 30450587, DOI: 10.1002/lary.27324.Peer-Reviewed Original ResearchConceptsSternoclavicular jointComputed tomographyMyocardial infarction/coronary artery diseaseMonths to 3 yearsBone scan uptakeIrreversible ischemic damagePublished case reportsSynergistic risk factorsComprehensive literature searchLaryngopharyngeal malignanciesConcurrent chemoradiationRadiation complicationsRadiation therapyRare manifestationSurgical explorationScan uptakeCase reportPosttreatment toxicityProspective InvestigationDiabetes mellitusPatient characteristicsArtery diseaseComplete healingAdequate treatmentBone erosion
2016
Asthma outcomes after adenotonsillectomy: A systematic review
Kohli N, DeCarlo D, Goldstein N, Silverman J. Asthma outcomes after adenotonsillectomy: A systematic review. International Journal Of Pediatric Otorhinolaryngology 2016, 90: 107-112. PMID: 27729114, DOI: 10.1016/j.ijporl.2016.08.030.Peer-Reviewed Original ResearchConceptsMarkers of asthma severityObstructive sleep apneaEffect of adenoidectomySleep apneaAsthma severityPediatric populationAirway diseaseSystematic reviewAsthma outcomesUpper airway inflammationIncreased risk of asthmaUpper airway diseaseRespiratory medication useHistory of asthmaModulation of asthmaClinically significant reductionDevelopment of asthmaRisk of asthmaAsthma-related exacerbationsLower airway diseaseCraniofacial syndromesProspective trialsDecreased asthma severityAsthma-related symptomsSignificant comorbidities
2015
Poly(lactic-co-glycolide) polymer constructs cross-linked with human BMP-6 and VEGF protein significantly enhance rat mandible defect repair
Das A, Fishero B, Christophel J, Li C, Kohli N, Lin Y, Dighe A, Cui Q. Poly(lactic-co-glycolide) polymer constructs cross-linked with human BMP-6 and VEGF protein significantly enhance rat mandible defect repair. Cell And Tissue Research 2015, 364: 125-135. PMID: 26475719, DOI: 10.1007/s00441-015-2301-x.Peer-Reviewed Original ResearchConceptsDelivery of vascular endothelial growth factorVascular endothelial growth factorPoly(lactic-co-glycolic acidMesenchymal stem cellsThree-dimensional scaffoldsPoly(lactic-co-glycolideBMP-6Rat mesenchymal stem cellsThermal sinteringDelivery of mesenchymal stem cellsSignificant bone regenerationCombined deliveryVascular endothelial growth factor proteinCritical-size mandibular defectsPLAGA microspheresRecombinant human vascular endothelial growth factorBone repairSprague Dawley ratsEndothelial growth factorBone repair siteHuman vascular endothelial growth factorEnhancement of angiogenesisBone morphogenetic protein 6Bone regenerationDays in vitro