Numerous isoforms of Fgf8 reflect its multiple roles in the developing brain
Sunmonu N, Li K, Li J. Numerous isoforms of Fgf8 reflect its multiple roles in the developing brain. Journal Of Cellular Physiology 2011, 226: 1722-1726. PMID: 21506104, PMCID: PMC3071877, DOI: 10.1002/jcp.22587.Peer-Reviewed Original ResearchConceptsVertebrate developmentDevelopment of multicellular organismsSplice variantsIsoform proteinsIntegration of cell proliferationRNA alternative splicingMouse Fgf8 geneFibroblast growth factorIn vivo functionMulticellular organismsAlternative splicingFate determinationSoluble growth factorsFgf8 geneN-terminiPolypeptide growth factorsGrowth factorFgf8Ligand-receptor systemSplicingVertebratesCell proliferationFunction of FGF8IsoformsProtein