Diversity in genetic risk of recurrent stroke: a genome-wide association study meta-analysis
Aldridge C, Armstrong N, Sunmonu N, Becker C, Palakshappa D, Lindgren A, Pedersen A, Stanne T, Jern C, Maguire J, Hsu F, Keene K, Sale M, Irvin M, Worrall B. Diversity in genetic risk of recurrent stroke: a genome-wide association study meta-analysis. Frontiers In Stroke 2024, 3: 1338636. DOI: 10.3389/fstro.2024.1338636.Peer-Reviewed Original ResearchPolygenic risk scoresAncestral groupsGenome-wide significant variantsGenome-wide association study meta-analysisGenetic riskRecurrent stroke riskGWAS modelsEffective allelesRisk of incident strokeGenetic lociAssociated with incident ischemic strokeRecurrent strokeStudy meta-analysisSignificant variantsStroke riskIncident ischemic strokeGenetic studiesBiological insightsEuropean ancestryGenetic associationGenesMYH11 geneBiological relevanceLong-term disabilityGWAS