2020
Gastroesophageal Reflux
Masoud A, Hinchcliff M. Gastroesophageal Reflux. In Clinical Practice 2020, 179-191. DOI: 10.1007/978-3-030-53736-4_16.Peer-Reviewed Original ResearchGastroesophageal refluxSystemic sclerosisGastric antral vascular ectasia (GAVE) syndromePatient-reported health-related qualityRheumatism 2013 classification criteriaRheumatology/European LeagueSmall bowel bacterial overgrowthMajor underlying pathologyHealth-related qualitySmooth muscle atrophyControl of refluxBowel bacterial overgrowthLower esophageal sphincterOptimal patient carePharyngeal symptomsAspiration pneumonitisFecal incontinencePeptic strictureAggressive preventionBacterial overgrowthGastric emptyingEsophageal sphincterUnderlying pathologyBarrett's esophagusEsophageal adenocarcinoma
2008
Systemic sclerosis/scleroderma: a treatable multisystem disease.
Hinchcliff M, Varga J. Systemic sclerosis/scleroderma: a treatable multisystem disease. American Family Physician 2008, 78: 961-8. PMID: 18953973.Peer-Reviewed Original ResearchConceptsInternal organ involvementSystemic sclerosisOrgan involvementRaynaud's phenomenonEndothelin-1 receptor blockerChronic connective tissue diseaseEnd-organ dysfunctionEnzyme inhibitor therapyHigh-dose corticosteroidsScleroderma renal crisisPulmonary arterial hypertensionPulmonary function testingConnective tissue diseaseDisease-modifying therapiesDistinct clinical subsetInternal organ dysfunctionOrgan-specific manifestationsPhosphodiesterase-5 inhibitorsMiddle-age womenOptimal patient careWidespread microvascular damageRenal crisisArterial hypertensionDigital ulcersLifestyle modification