2022
Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS)
Abdo M, Kunisaki K, Morris A, Stosor V, Chang D, D'Souza G, Crothers K, Abdel-Maksoud M, DiGuiseppi C, Brown T, MaWhinney S, Erlandson K. Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS). Annals Of Epidemiology 2022, 76: 50-60. PMID: 36244514, PMCID: PMC9881119, DOI: 10.1016/j.annepidem.2022.10.005.Peer-Reviewed Original ResearchConceptsMulticenter AIDS Cohort StudyWeak grip strengthGait speedGrip strengthPhysical functionPulmonary impairmentPulmonary functionGreater oddsSimilar gait speedSlow gait speedPhysical function limitationsAIDS Cohort StudyCohort study dataNormal FEVCohort studyMedian ageHIV serostatusHIVFunction limitationsFEVDlPhysical outcomesAgeFrailtyMen
2020
Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV.
Pelloquin R, Abdo M, MaWhinney S, Jankowski CM, Erlandson KM. Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 85: 372-378. PMID: 32732769, PMCID: PMC7572796, DOI: 10.1097/qai.0000000000002455.Peer-Reviewed Original ResearchConceptsPhysical function measuresTime-dependent receiverVACS IndexPhysical functionGrip strengthFunction measuresCross-sectional cohort studyPhysical function impairmentPhysical function variablesSex-adjusted modelsHazard of mortalityMiddle-aged populationSpecific patient subpopulationsPrediction of survivalMiddle-aged adultsOnly significant improvementElectronic health recordsVACS scoresCohort studyFrailty toolsFunction impairmentPatient subpopulationsVAC indexMortality predictionPWH
2018
Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus
Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus. Clinical Infectious Diseases 2018, 68: 131-138. PMID: 29788039, PMCID: PMC6293002, DOI: 10.1093/cid/ciy430.Peer-Reviewed Original ResearchConceptsPoor health outcomesHuman immunodeficiency virusNeurocognitive impairmentHealth outcomesImmunodeficiency virusPrevalence ratiosMedian CD4 countOutcomes of fallsOverlap of frailtyPresence of frailtyHIV-1 RNACopies/mLPoisson regression modelsCD4 countRecurrent fallsMedian ageIADL limitationsObservational studyDaily livingAdjusted modelPLWHFrailtySignificant associationGreater riskMost participants
2017
Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults
Tassiopoulos K, Abdo M, Wu K, Koletar SL, Palella FJ, Kalayjian R, Taiwo B, Erlandson KM. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS 2017, 31: 2287-2294. PMID: 28991026, PMCID: PMC5654616, DOI: 10.1097/qad.0000000000001613.Peer-Reviewed Original ResearchConceptsRecurrent fallsFrailty assessmentGrip strengthSelf-reported weight lossLogistic regressionContribution of frailtyMulticenter cohort studyLow physical activityRisk of fallsPotential target populationOlder HIVCohort studyBaseline frailtyPeripheral neuropathyEffect modificationFrail individualsMultivariable modelFrail personsPhysical activityClinical careMultinomial logistic regressionHIVNonfrail individualsPrefrailSignificant association