2023
Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study
Abdo M, Kunisaki K, Morris A, Stosor V, Chang D, D'Souza G, Crothers K, Abdel-Maksoud M, DiGuiseppi C, Brown T, Erlandson K, MaWhinney S. Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study. AIDS Research And Human Retroviruses 2023, 39: 621-632. PMID: 37276144, PMCID: PMC10712368, DOI: 10.1089/aid.2023.0001.Peer-Reviewed Original ResearchConceptsPulmonary impairmentPulmonary functionOdds ratioMedian age 57 yearsMulticenter AIDS Cohort StudyGreater respiratory impairmentPulmonary function impairmentImpaired pulmonary functionAge 57 yearsHealth-related qualityLower physical HRQoLRespiratory health statusAIDS Cohort StudyCohort study dataQuality of lifeHRQoL scoresCohort studyLower HRQoLPhysical HRQoLHIV serostatusAdjusted analysisFunction impairmentRespiratory impairmentMmHg decreaseRespiratory health
2022
Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study
Abdo M, Wu X, Sharma A, Tassiopoulos KK, Brown TT, Koletar SL, Yin MT, Erlandson KM. Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study. AIDS Research And Human Retroviruses 2022, 38: 530-537. PMID: 35018800, PMCID: PMC9297325, DOI: 10.1089/aid.2021.0162.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedAgingFemaleHIV InfectionsHumansImmunityLongitudinal StudiesMaleMiddle AgedRisk FactorsConceptsRecurrent fallsPhysical activityOlder PWHHigher oddsWomen's Interagency HIV StudyBody mass indexLong-term observational studyHigh physical activityOlder U.S. womenLogistic regression modelsSemiannual visitsMultinomial logistic regression modelsHIV infectionMedian ageStudy entryMultivariable analysisObese individualsHIV StudyEffect modificationObservational studyFall assessmentGeographic regionsU.S. womenGreater riskHIV
2021
Risk Factors for Hospitalization in People With HIV and COVID-19
Kamis KF, Barbera L, Abdo M, Rowan SE, Hussain C, Gardner EM, Johnson SC, MaWhinney S, Davis AJ, Carlson J, Kozacka KA, Erlandson KM. Risk Factors for Hospitalization in People With HIV and COVID-19. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 88: e22-e22. PMID: 34334740, PMCID: PMC8518201, DOI: 10.1097/qai.0000000000002780.Peer-Reviewed Original ResearchA Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study
Dillon SM, Abdo MH, Wilson MP, Liu J, Jankowski CM, Robertson CE, Tuncil Y, Hamaker B, Frank DN, MaWhinney S, Wilson CC, Erlandson KM. A Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study. AIDS Research And Human Retroviruses 2021, 37: 542-550. PMID: 33787299, PMCID: PMC8260890, DOI: 10.1089/aid.2020.0283.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBody CompositionGastrointestinal MicrobiomeHIV InfectionsHumansInflammationMicrobiotaMiddle AgedConceptsPhysical functionOlder PWHOlder personsMuscle functionLean massLower short physical performance battery scoresBody compositionShort Physical Performance Battery scoreLower extremity muscle functionPhysical Performance Battery scoreGut microbiomeStool SCFA levelsEffective antiretroviral therapyPhysical function measurementsBetter muscle functionFunction axisAntiretroviral therapySCFA levelsHIV serostatusSPPB scoreUninfected personsSCFA butyrateGrip strengthUninfected controlsPWHEffect of Statin Therapy on Age-Associated Changes in Physical Function Among Men With and Without HIV in the Multicenter AIDS Cohort Study.
Abdo M, Langan SJ, MaWhinney S, Sun J, Lake JE, Palella FJ, Kingsley L, Brown TT, Erlandson KM. Effect of Statin Therapy on Age-Associated Changes in Physical Function Among Men With and Without HIV in the Multicenter AIDS Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 86: 455-462. PMID: 33230030, PMCID: PMC8193908, DOI: 10.1097/qai.0000000000002579.Peer-Reviewed Original ResearchConceptsStatin usePhysical functionStatin usersHIV serostatusGait speedMulticenter AIDS Cohort StudyBaseline median ageGrip strength declineCardiovascular risk factorsGait speed declineAIDS Cohort StudyAge-Associated ChangesYears of ageLong-term riskStatin therapyCohort studyMedian ageGrip strengthRisk factorsHIVStudy menSpeed declineAgeMenSerostatus
2020
Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV.
Pelloquin R, Abdo M, MaWhinney S, Jankowski CM, Erlandson KM. Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 85: 372-378. PMID: 32732769, PMCID: PMC7572796, DOI: 10.1097/qai.0000000000002455.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFrailtyHIV InfectionsHIV-1HumansMaleMiddle AgedPhysical Functional PerformanceRisk FactorsConceptsPhysical function measuresTime-dependent receiverVACS IndexPhysical functionGrip strengthFunction measuresCross-sectional cohort studyPhysical function impairmentPhysical function variablesSex-adjusted modelsHazard of mortalityMiddle-aged populationSpecific patient subpopulationsPrediction of survivalMiddle-aged adultsOnly significant improvementElectronic health recordsVACS scoresCohort studyFrailty toolsFunction impairmentPatient subpopulationsVAC indexMortality predictionPWHEnd-of-Life Planning Prior to Death Among People Living With HIV.
Abdo M, Ressler A, MaWhinney S, Jankowski C, Johnson SC, Erlandson KM. End-of-Life Planning Prior to Death Among People Living With HIV. Journal Of The Association Of Nurses In AIDS Care 2020, 32: 127-133. PMID: 32058335, PMCID: PMC8849137, DOI: 10.1097/jnc.0000000000000162.Peer-Reviewed Original Research
2019
Examining Mortality to Identify Opportunities for Improved Care Among Adults with HIV in a Single Academic Medical Center
Ressler AM, Abdo M, MaWhinney S, Johnson SC, Erlandson KM. Examining Mortality to Identify Opportunities for Improved Care Among Adults with HIV in a Single Academic Medical Center. AIDS Research And Human Retroviruses 2019, 35: 1082-1088. PMID: 31432692, PMCID: PMC6862946, DOI: 10.1089/aid.2019.0154.Peer-Reviewed Original ResearchConceptsSingle academic medical centerProportion of deathsAcademic medical centerMedical CenterElectronic medical record queryNon-AIDS malignanciesMedical record queryProportion of AIDSAvailable medical recordsCause of deathColon cancer screeningPrevention of malignancyAIDS malignanciesEligible patientsHIV causesCardiac causesComorbid illnessesChart reviewPatient ageCancer screeningMedical recordsUnknown causeLaboratory valuesProvider surveyCoding Causes
2018
Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus
Erlandson KM, Perez J, Abdo M, Robertson K, Ellis RJ, Koletar SL, Kalayjian R, Taiwo B, Palella FJ, Tassiopoulos K. Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus. Clinical Infectious Diseases 2018, 68: 131-138. PMID: 29788039, PMCID: PMC6293002, DOI: 10.1093/cid/ciy430.Peer-Reviewed Original ResearchMeSH KeywordsAdultClinical Decision RulesCognitive DysfunctionFrailtyHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPrognosisConceptsPoor health outcomesHuman immunodeficiency virusNeurocognitive impairmentHealth outcomesImmunodeficiency virusPrevalence ratiosMedian CD4 countOutcomes of fallsOverlap of frailtyPresence of frailtyHIV-1 RNACopies/mLPoisson regression modelsCD4 countRecurrent fallsMedian ageIADL limitationsObservational studyDaily livingAdjusted modelPLWHFrailtySignificant associationGreater riskMost participants
2017
Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults
Tassiopoulos K, Abdo M, Wu K, Koletar SL, Palella FJ, Kalayjian R, Taiwo B, Erlandson KM. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS 2017, 31: 2287-2294. PMID: 28991026, PMCID: PMC5654616, DOI: 10.1097/qad.0000000000001613.Peer-Reviewed Original ResearchConceptsRecurrent fallsFrailty assessmentGrip strengthSelf-reported weight lossLogistic regressionContribution of frailtyMulticenter cohort studyLow physical activityRisk of fallsPotential target populationOlder HIVCohort studyBaseline frailtyPeripheral neuropathyEffect modificationFrail individualsMultivariable modelFrail personsPhysical activityClinical careMultinomial logistic regressionHIVNonfrail individualsPrefrailSignificant association