2022
Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS)
Abdo M, Kunisaki K, Morris A, Stosor V, Chang D, D'Souza G, Crothers K, Abdel-Maksoud M, DiGuiseppi C, Brown T, MaWhinney S, Erlandson K. Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS). Annals Of Epidemiology 2022, 76: 50-60. PMID: 36244514, PMCID: PMC9881119, DOI: 10.1016/j.annepidem.2022.10.005.Peer-Reviewed Original ResearchConceptsMulticenter AIDS Cohort StudyWeak grip strengthGait speedGrip strengthPhysical functionPulmonary impairmentPulmonary functionGreater oddsSimilar gait speedSlow gait speedPhysical function limitationsAIDS Cohort StudyCohort study dataNormal FEVCohort studyMedian ageHIV serostatusHIVFunction limitationsFEVDlPhysical outcomesAgeFrailtyMenRegional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study
Abdo M, Wu X, Sharma A, Tassiopoulos KK, Brown TT, Koletar SL, Yin MT, Erlandson KM. Regional Differences in Risk of Recurrent Falls Among Older U.S. Women and Men with HIV in the HIV Infection, Aging, and Immune Function Long-Term Observational Study. AIDS Research And Human Retroviruses 2022, 38: 530-537. PMID: 35018800, PMCID: PMC9297325, DOI: 10.1089/aid.2021.0162.Peer-Reviewed Original ResearchConceptsRecurrent fallsPhysical activityOlder PWHHigher oddsWomen's Interagency HIV StudyBody mass indexLong-term observational studyHigh physical activityOlder U.S. womenLogistic regression modelsSemiannual visitsMultinomial logistic regression modelsHIV infectionMedian ageStudy entryMultivariable analysisObese individualsHIV StudyEffect modificationObservational studyFall assessmentGeographic regionsU.S. womenGreater riskHIV
2021
Effect of Statin Therapy on Age-Associated Changes in Physical Function Among Men With and Without HIV in the Multicenter AIDS Cohort Study.
Abdo M, Langan SJ, MaWhinney S, Sun J, Lake JE, Palella FJ, Kingsley L, Brown TT, Erlandson KM. Effect of Statin Therapy on Age-Associated Changes in Physical Function Among Men With and Without HIV in the Multicenter AIDS Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 86: 455-462. PMID: 33230030, PMCID: PMC8193908, DOI: 10.1097/qai.0000000000002579.Peer-Reviewed Original ResearchConceptsStatin usePhysical functionStatin usersHIV serostatusGait speedMulticenter AIDS Cohort StudyBaseline median ageGrip strength declineCardiovascular risk factorsGait speed declineAIDS Cohort StudyAge-Associated ChangesYears of ageLong-term riskStatin therapyCohort studyMedian ageGrip strengthRisk factorsHIVStudy menSpeed declineAgeMenSerostatus
2017
Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults
Tassiopoulos K, Abdo M, Wu K, Koletar SL, Palella FJ, Kalayjian R, Taiwo B, Erlandson KM. Frailty is strongly associated with increased risk of recurrent falls among older HIV-infected adults. AIDS 2017, 31: 2287-2294. PMID: 28991026, PMCID: PMC5654616, DOI: 10.1097/qad.0000000000001613.Peer-Reviewed Original ResearchConceptsRecurrent fallsFrailty assessmentGrip strengthSelf-reported weight lossLogistic regressionContribution of frailtyMulticenter cohort studyLow physical activityRisk of fallsPotential target populationOlder HIVCohort studyBaseline frailtyPeripheral neuropathyEffect modificationFrail individualsMultivariable modelFrail personsPhysical activityClinical careMultinomial logistic regressionHIVNonfrail individualsPrefrailSignificant association