Featured Publications
Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides
Sawano M, Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Kohno T, Anzai T, Fukuda K, Yoshikawa T. Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides. ESC Heart Failure 2018, 5: 610-619. PMID: 29520978, PMCID: PMC6073038, DOI: 10.1002/ehf2.12278.Peer-Reviewed Original ResearchConceptsMAGGIC scoreBNP levelsB-type natriuretic peptide levelsAcute Heart Failure registryChronic Heart Failure (MAGGIC) scoreConsecutive acute HF patientsHeart failure patient outcomesHeart Failure Risk ScoreMeta-Analysis Global GroupAcute HF patientsHeart Failure RegistryHeart failure scoreProspective multicentre registryIncremental prognostic valueNatriuretic peptide levelsHeart failure patientsMulticentre registryHF patientsFailure patientsYear mortalityNatriuretic peptidePatient mortalityPrognostic valueMean ageJapanese Registry
2019
Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure
Shoji S, Shiraishi Y, Sawano M, Katsumata Y, Yuasa S, Kohno T, Fukuda K, Spertus J, Kohsaka S. Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure. Heart And Vessels 2019, 34: 1464-1470. PMID: 30887105, DOI: 10.1007/s00380-019-01378-1.Peer-Reviewed Original ResearchConceptsClinical risk scorePatient-reported qualityLong-term prognosisHeart failureHHF patientsRisk scoreComposite outcomeAcute settingGWTG-HF risk scoreHospitalized HF patientsAcute heart failureChronic heart failurePrimary therapeutic targetHealth care providersFirst yearCause mortalityHF patientsHF readmissionPatient characteristicsIndependent predictorsAcute phasePrognostic indicatorJapanese patientsPrognostic assessmentCare providers
2018
Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
Isobe S, Itabashi Y, Kawakami T, Kataoka M, Kohsaka S, Tsugu T, Kimura M, Sawano M, Katsuki T, Kohno T, Endo J, Murata M, Fukuda K. Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension. Heart And Vessels 2018, 34: 688-697. PMID: 30386916, DOI: 10.1007/s00380-018-1284-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiographyAngioplasty, BalloonCardiac CatheterizationChronic DiseaseEchocardiographyFemaleFollow-Up StudiesGlomerular Filtration RateHumansHypertension, PulmonaryMaleMiddle AgedOxygenOxygen ConsumptionPrognosisPulmonary ArteryPulmonary EmbolismRetrospective StudiesVascular ResistanceVentricular Function, RightConceptsChronic thromboembolic pulmonary hypertensionBalloon pulmonary angioplastyInoperable chronic thromboembolic pulmonary hypertensionFinal BPARight heart functionThromboembolic pulmonary hypertensionRenal functionVenous oxygen saturationPulmonary hypertensionClinical characteristicsOxygen saturationHeart functionMean pulmonary arterial pressureMixed venous oxygen saturationPulmonary vascular resistancePulmonary arterial pressureGlomerular filtration ratePatients' clinical characteristicsBalloon pulmonaryImproved eGFRPulmonary angioplastyCardiac indexCTEPH patientsVascular resistanceArterial pressureValidation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients
Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, Nagatomo Y, Sujino Y, Fukuoka R, Sawano M, Kohno T, Fukuda K, Anzai T, Shadman R, Dardas T, Levy W, Yoshikawa T. Validation and Recalibration of Seattle Heart Failure Model in Japanese Acute Heart Failure Patients. Journal Of Cardiac Failure 2018, 25: 561-567. PMID: 30099192, DOI: 10.1016/j.cardfail.2018.07.463.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure patientsHF patientsHeart failure modelHFrEF patientsHFpEF patientsEjection fractionFailure patientsAcute heart failure patientsAcute HF patientsConventional clinical variablesJapanese HF patientsReduced ejection fractionPrecise risk stratificationAcute decompensationHeart failureHospital admissionNational CerebralRisk stratificationClinical variablesC-statisticHeart failure databaseModest discriminationPatientsMedical resourcesValidation of U.S. mortality prediction models for hospitalized heart failure in the United Kingdom and Japan
Nagai T, Sundaram V, Shoaib A, Shiraishi Y, Kohsaka S, Rothnie K, Piper S, McDonagh T, Hardman S, Goda A, Mizuno A, Sawano M, Rigby A, Quint J, Yoshikawa T, Clark A, Anzai T, Cleland J. Validation of U.S. mortality prediction models for hospitalized heart failure in the United Kingdom and Japan. European Journal Of Heart Failure 2018, 20: 1179-1190. PMID: 29846026, DOI: 10.1002/ejhf.1210.Peer-Reviewed Original Research
2017
Characteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention
Hirota Y, Sawano M, Numasawa Y, Ueda I, Noma S, Suzuki M, Hayashida K, Yuasa S, Maekawa Y, Kohsaka S, Fukuda K. Characteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention. Cardiovascular Intervention And Therapeutics 2017, 33: 154-162. PMID: 28585049, DOI: 10.1007/s12928-017-0471-z.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCoronary artery diseaseMulti-vessel diseaseClassical risk factorsCardiogenic shockYounger patientsACS patientsHospital mortalityCoronary syndromeCulprit lesionRisk factorsFamily historyPremature coronary artery diseaseHigher body mass indexPercutaneous coronary intervention registryConsecutive ACS patientsYoung ACS patientsPrevalence of dyslipidemiaChronic kidney diseasePercutaneous coronary interventionCoronary Intervention RegistryBody mass indexCS presentationLonger life expectancyHospital outcomes
2016
Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study
Sawano M, Kohsaka S, Okamura T, Inohara T, Sugiyama D, Shiraishi Y, Watanabe M, Nakamura Y, Higashiyama A, Kadota A, Okuda N, Murakami Y, Ohkubo T, Fujiyoshi A, Miura K, Okayama A, Ueshima H, . Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study. PLOS ONE 2016, 11: e0157563. PMID: 27362562, PMCID: PMC4928789, DOI: 10.1371/journal.pone.0157563.Peer-Reviewed Original ResearchConceptsFramingham risk scoreCardiovascular deathRisk chartsRisk scoreCohort studyLong-term cardiovascular deathLong-term prognostic effectLong-term cardiovascular outcomesProspective cohort studyIndependent prognostic valueLongitudinal cohort studyRisk stratification systemCause deathCardiovascular outcomesCoronary deathElectrocardiogram findingsHazard ratioPrognostic impactStroke deathsElectrocardiographic findingsPrognostic effectPrognostic valueHealthy menRepolarization abnormalitiesHigh risk
2015
Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level
Shiraishi Y, Kohsaka S, Abe T, Mizuno A, Goda A, Izumi Y, Yagawa M, Akita K, Sawano M, Inohara T, Takei M, Kohno T, Higuchi S, Yamazoe M, Mahara K, Fukuda K, Yoshikawa T, Investigators W. Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level. American Heart Journal 2015, 171: 33-39. PMID: 26699598, DOI: 10.1016/j.ahj.2015.10.008.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptide levelsGWTG-HF risk scoreAcute heart failureNatriuretic peptide levelsHospital mortalityRisk scorePeptide levelsAHF patientsC-statisticGuidelines-Heart Failure (GWTG-HF) risk scoreWest Tokyo Heart Failure registryChronic obstructive pulmonary diseaseBlood urea nitrogen levelsGWTG-HF scoreHeart Failure RegistryMulticenter cohort registryRisk score performanceObstructive pulmonary diseaseSystolic blood pressureUrea nitrogen levelsHosmer-Lemeshow statisticFuture risk modelsCohort registryBlood pressureHeart failure
2014
Prognostic impact of renal and hepatic dysfunction based on the MELD-XI score in patients with acute heart failure
Inohara T, Kohsaka S, Shiraishi Y, Goda A, Sawano M, Yagawa M, Mahara K, Fukuda K, Yoshikawa T, Investigators W. Prognostic impact of renal and hepatic dysfunction based on the MELD-XI score in patients with acute heart failure. International Journal Of Cardiology 2014, 176: 571-573. PMID: 25305701, DOI: 10.1016/j.ijcard.2014.08.052.Peer-Reviewed Original ResearchPrognostic Implication of Physical Signs of Congestion in Acute Heart Failure Patients and Its Association with Steady-State Biomarker Levels
Negi S, Sawano M, Kohsaka S, Inohara T, Shiraishi Y, Kohno T, Maekawa Y, Sano M, Yoshikawa T, Fukuda K. Prognostic Implication of Physical Signs of Congestion in Acute Heart Failure Patients and Its Association with Steady-State Biomarker Levels. PLOS ONE 2014, 9: e96325. PMID: 24802880, PMCID: PMC4011709, DOI: 10.1371/journal.pone.0096325.Peer-Reviewed Original ResearchConceptsJugular venous distensionAcute heart failurePulmonary ralesTime of dischargePhysical findingsReadmission ratesAHF patientsAcute heart failure patientsElevated troponin T levelsSingle-center university hospitalConsecutive AHF patientsElevated TnT levelsParoxysmal nocturnal dyspneaNon-ischemic etiologyTroponin T levelsHeart failure patientsNon-ischemic cardiomyopathyLong-term outcomesTime of admissionThird heart soundNocturnal dyspneaMean followPrimary endpointVenous distensionFailure patients