2025
Heterogeneous associations between short-term ambient ozone exposure and morbidities from infants to seniors: A nationwide case-crossover study in South Korea
Ahn S, Kang C, Oh J, Yun H, Ahn S, Kim A, Kwon D, Park J, Jang H, Kim E, Bell M, Kim H, Lee W. Heterogeneous associations between short-term ambient ozone exposure and morbidities from infants to seniors: A nationwide case-crossover study in South Korea. Journal Of Hazardous Materials Advances 2025, 17: 100531. DOI: 10.1016/j.hazadv.2024.100531.Peer-Reviewed Original ResearchED admissionMental disordersWarm-season ozoneTargeted public health policiesCase-crossover designNational Health Insurance databaseCase-crossover studyMiddle-aged populationPublic health policiesIndividuals aged 0Health Insurance DatabaseED admission dataHealth policyExcess riskRespiratory diseaseAmbient ozoneAmbient ozone exposureShort-term ozoneEmergency departmentAdmission dataAdmission costsInsurance DatabaseAged 0Heterogeneous associationsAdult age
2024
The impact of exposure assessment on associations between air pollution and cardiovascular mortality risks in the city of Rio de Janeiro, Brazil
Heo S, Schuch D, Junger W, Zhang Y, de Fatima Andrade M, Bell M. The impact of exposure assessment on associations between air pollution and cardiovascular mortality risks in the city of Rio de Janeiro, Brazil. Environmental Research 2024, 263: 120150. PMID: 39414104, DOI: 10.1016/j.envres.2024.120150.Peer-Reviewed Original ResearchAir pollutionCardiovascular mortality riskExposure assessmentMortality riskExposure methodHealth risk estimatesAir pollution risksAir quality modelsExposure levelsOdds ratioHealth impact assessmentAssociated with mortality riskPollution riskConfidence intervalsCardiovascular mortality dataComplex air quality modelRio de JaneiroCase-crossover studyEstimate mortality riskWRF-ChemCity of Rio de JaneiroMonitoring networkInterquartile rangeMultiple logistic regressionImpact assessmentAssociation between heat and hospital admissions in people with disabilities in South Korea: a nationwide, case-crossover study
Park J, Kim A, Kim Y, Choi M, Yoon T, Kang C, Kang H, Oh J, Bell M, Kim H, Lee W. Association between heat and hospital admissions in people with disabilities in South Korea: a nationwide, case-crossover study. The Lancet Planetary Health 2024, 8: e217-e224. PMID: 38580423, DOI: 10.1016/s2542-5196(24)00027-5.Peer-Reviewed Original ResearchConceptsEmergency department admissionsBrain lesion disordersCase-crossover studyPhysical disabilityOdds ratioCase-crossover designSample Cohort databaseConditional logistic regressionAssociated with increased riskExcess medical costsNon-disabled populationSevere physical disabilitiesHearing lossEnvironmental heat exposureCohort databaseHospital admissionMental disordersLogistic regressionMedical costsDisabilityAdmissionAction planHigh heat risksKorean Ministry of EducationNational Research Foundation
2023
Effects of heat waves on cardiovascular and respiratory mortality in Rio de Janeiro, Brazil
Silveira I, Cortes T, Bell M, Junger W. Effects of heat waves on cardiovascular and respiratory mortality in Rio de Janeiro, Brazil. PLOS ONE 2023, 18: e0283899. PMID: 37000782, PMCID: PMC10065291, DOI: 10.1371/journal.pone.0283899.Peer-Reviewed Original ResearchConceptsRespiratory mortalityOdds ratioDistributed lag non-linear modelCardiovascular mortalityIndividual-level exposuresHeat wave intensityCase-crossover studyConditional logistic regressionMunicipal Health DepartmentHeat wavesEffects of heat wavesHealth impacts of heat wavesHealth departmentsHealth resourcesDeath dataOlder peopleLow-incomeEffect estimatesOlder womenDefinition of heat wavesLogistic regressionEpidemiological evidenceMorbidity outcomesHeat wave daysHealth impacts
2022
Association between Short-Term Exposure to Air Pollution and COVID-19 Mortality: A Population-Based Case-Crossover Study Using Individual-Level Mortality Registry Confirmed by Medical Examiners
Kim H, Samet J, Bell M. Association between Short-Term Exposure to Air Pollution and COVID-19 Mortality: A Population-Based Case-Crossover Study Using Individual-Level Mortality Registry Confirmed by Medical Examiners. Environmental Health Perspectives 2022, 130: 117006. PMID: 36367781, PMCID: PMC9651183, DOI: 10.1289/ehp10836.Peer-Reviewed Original ResearchConceptsCOVID-19 mortalityShort-term exposureCOVID-19Cook County Medical Examiner's OfficeTime-stratified case-crossover designCounty Medical Examiner's OfficeRisk of mortalityCase-crossover studyInterquartile range increaseLocation of deathCase-crossover analysisCase-crossover designDay of deathIndications of modificationMedical Examiner's OfficeAmbient air pollutionCOVID-19 deathsRace/ethnicityComorbid conditionsMortality registryPotential confoundersMortality burdenIQR increaseEpidemiological studiesMortalityLow temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients
Zhang Q, Peng L, Hu J, Li H, Jiang Y, Fang W, Yan H, Chen J, Wang W, Xiang D, Su X, Yu B, Wang Y, Xu Y, Wang L, Li C, Chen Y, Zhao D, Ge W, Bell M, Gasparrini A, Ge J, Huo Y, Kan H. Low temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients. The Lancet Regional Health - Western Pacific 2022, 28: 100562. PMID: 35991537, PMCID: PMC9386641, DOI: 10.1016/j.lanwpc.2022.100562.Peer-Reviewed Original ResearchAcute aortic dissectionAAD onsetDisease burdenAAD casesLife-threatening cardiovascular emergencyTime-stratified case-crossover studyAortic dissection riskCorresponding disease burdenGreat public health significanceModifiable risk factorsConditional logistic regressionCase-crossover studyLarge nationwide studyCase-crossover analysisMedical Research Council UKPublic health significanceAortic dissectionAssociation of temperatureCardiovascular emergenciesResearch Council UKRisk factorsAttributable fractionExposure-response curvesCumulative relative riskRelative riskHourly Air Pollutants and Acute Coronary Syndrome Onset in 1.29 Million Patients
Chen R, Jiang Y, Hu J, Chen H, Li H, Meng X, Ji J, Gao Y, Wang W, Liu C, Fang W, Yan H, Chen J, Wang W, Xiang D, Su X, Yu B, Wang Y, Xu Y, Wang L, Li C, Chen Y, Bell M, Cohen A, Ge J, Huo Y, Kan H. Hourly Air Pollutants and Acute Coronary Syndrome Onset in 1.29 Million Patients. Circulation 2022, 145: 1749-1760. PMID: 35450432, DOI: 10.1161/circulationaha.121.057179.Peer-Reviewed Original ResearchConceptsAir pollutionParticulate matterAir pollutants PM<sub>2.5</sub>, PConcentrations of PM<sub>2.5</sub>Short-term exposure to ambient air pollutionWorld Health Organization air quality guidelinesHourly concentrations of fine particulate matterConcentrations of fine particulate matterExposure to ambient air pollutionAir quality guidelinesCoarse particulate matterFine particulate matterCriteria air pollutantsAmbient air pollutionHourly air pollutionInterquartile range increaseQuality guidelinesHourly concentrationsAcute coronary syndromeCase-crossover studySORange increaseNitrogen dioxidePollutionSulfur dioxide
2017
Particulate Matter and Risk of Hospital Admission in the Kathmandu Valley, Nepal: A Case-Crossover Study
Gurung A, Son JY, Bell ML. Particulate Matter and Risk of Hospital Admission in the Kathmandu Valley, Nepal: A Case-Crossover Study. American Journal Of Epidemiology 2017, 186: 573-580. PMID: 28911012, DOI: 10.1093/aje/kwx135.Peer-Reviewed Original ResearchConceptsHealth burdenTime-stratified case-crossover analysisRisk of hospitalizationSubstantial health burdenInpatient hospitalization dataCase-crossover studyPotential effect modifiersCase-crossover analysisMajority of evidenceHospital admissionEffect modificationCardiovascular admissionsHospitalization dataM3 increaseEffect modifiersMajor hospitalsSocioeconomic statusHospitalizationAdmissionHuman health burdenKathmandu ValleyCentral data collection systemBurdenAir pollutionAerodynamic diameter