2017
Membrane Currents, Gene Expression, and Circadian Clocks
Allen CN, Nitabach MN, Colwell CS. Membrane Currents, Gene Expression, and Circadian Clocks. Cold Spring Harbor Perspectives In Biology 2017, 9: a027714. PMID: 28246182, PMCID: PMC5411696, DOI: 10.1101/cshperspect.a027714.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCell MembraneCircadian ClocksCircadian RhythmGene Expression RegulationHumansNeuronsConceptsCircadian clockGene ClockMembrane electrical activityCyclic adenosine monophosphateCircadian clock neuronsCircadian outputClock neuronsGenetic clockGene expressionCircadian oscillatorIntracellular CaAdenosine monophosphateFeedback loopPathwayClockHuman healthAction potential firing patternsMammalianActivityAction potential firingNightly reductionsMultiple typesExpressionMembrane currentsCircadian pattern
2016
Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature Preference
Goda T, Tang X, Umezaki Y, Chu ML, Kunst M, Nitabach MNN, Hamada FN. Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature Preference. Journal Of Neuroscience 2016, 36: 11739-11754. PMID: 27852781, PMCID: PMC5125228, DOI: 10.1523/jneurosci.0964-16.2016.Peer-Reviewed Original Research
2013
O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination
Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X. O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination. Cell Metabolism 2013, 17: 303-310. PMID: 23395176, PMCID: PMC3647362, DOI: 10.1016/j.cmet.2012.12.015.Peer-Reviewed Original ResearchConceptsCircadian clockProtein modificationNutrient-sensing pathwaysO-GlcNAc signalingHexosamine biosynthesis pathwayCovalent protein modificationBiosynthesis pathwayGlcNAc transferaseNutritional signalsClock oscillationsO-GlcNAcylationAberrant circadian rhythmsClock targetsOGT expressionCircadian oscillationsUbiquitinationN-acetylglucosamineNutrient fluxesMetabolic oscillationsBMAL1GenesPathwayCircadian rhythmKey mechanismClock
2011
Insect circadian clock outputs
Helfrich-Förster C, Nitabach MN, Holmes TC. Insect circadian clock outputs. Essays In Biochemistry 2011, 49: 87-101. PMID: 21819386, DOI: 10.1042/bse0490087.Peer-Reviewed Original ResearchConceptsClock neuronsDaily rhythmsCircadian clock outputBrain clockCellular clocksDrosophila fliesCircadian timekeeping systemCircadian outputEnvironmental cuesClock outputMigratory locustInsectsTimekeeping systemCircadian rhythmicitySubstantial similarityClockImpressive varietyButterfliesLocal environmentFliesClock circuitEntire lifeLocustTimekeeperPhysiology