2024
Invasive Versus Conservative Strategy in Older Adults ≥75 Years of Age With Non-ST-segment-Elevation Acute Coronary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Rout A, Moumneh M, Kalra K, Singh S, Garg A, Kunadian V, Biscaglia S, Alkhouli M, Rymer J, Batchelor W, Nanna M, Damluji A. Invasive Versus Conservative Strategy in Older Adults ≥75 Years of Age With Non-ST-segment-Elevation Acute Coronary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal Of The American Heart Association 2024, 13: e036151. PMID: 39494560, DOI: 10.1161/jaha.124.036151.Peer-Reviewed Original ResearchConceptsNon-ST segment elevation acute coronary syndromeAcute coronary syndromeComposite of deathBurden of geriatric conditionsRandomized controlled trialsCoronary syndromeMyocardial infarctionYears of ageInvasive strategyOlder adultsControlled trialsGeriatric conditionsOlder patientsCardiovascular deathOdds ratioMeta-analysis of randomized controlled trialsNon-ST segment elevationSecondary end pointsMeta-analysisFixed effects meta-analysisAll-cause deathEffects meta-analysisYounger patientsFollow-upDecreased risk
2023
Hierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease
Damluji A, Ijaz N, Chung S, Xue Q, Hasan R, Batchelor W, Orkaby A, Kochar A, Nanna M, Roth D, Walston J, Resar J, Gerstenblith G. Hierarchical Development of Physical Frailty and Cognitive Impairment and Their Association With Incident Cardiovascular Disease. JACC Advances 2023, 2: 100318. PMID: 37538136, PMCID: PMC10399211, DOI: 10.1016/j.jacadv.2023.100318.Peer-Reviewed Original ResearchMajor adverse cardiovascular eventsAdverse cardiovascular eventsCognitive impairmentCardiovascular eventsCardiovascular outcomesCardiovascular riskCardiovascular diseaseIncident major adverse cardiovascular eventsOlder adultsAdverse cardiovascular outcomesIncident cardiovascular diseasePhysical frailty phenotypeCoronary artery diseaseMultiple chronic conditionsPoor health outcomesAging Trends StudyFrailty phenotypeArtery diseasePrimary outcomeGeriatric conditionsChronic conditionsNational HealthPhysical frailtyStudy populationHigh risk