2021
The neural G protein Gαo tagged with GFP at an internal loop is functional in Caenorhabditis elegans
Kumar S, Olson AC, Koelle MR. The neural G protein Gαo tagged with GFP at an internal loop is functional in Caenorhabditis elegans. G3: Genes, Genomes, Genetics 2021, 11: jkab167. PMID: 34003969, PMCID: PMC8496287, DOI: 10.1093/g3journal/jkab167.Peer-Reviewed Original ResearchConceptsGreen fluorescent proteinCaenorhabditis elegansGenetic analysisHeterotrimeric G proteinsG protein GαoInternal loopC. elegansProtein complexesBiochemical purificationEpitope tagPlasma membraneAlpha subunitMolecular mechanismsFluorescent proteinGenetic studiesElegansGαoG proteinsEgg layingTransgenic expressionBiochemical studiesGαo proteinsBody morphologyProteinNeurotransmitter release
2006
Heterotrimeric G Protein Signaling: Getting inside the Cell
Koelle MR. Heterotrimeric G Protein Signaling: Getting inside the Cell. Cell 2006, 126: 25-27. PMID: 16839871, DOI: 10.1016/j.cell.2006.06.026.Peer-Reviewed Original Research
1997
A new family of G-protein regulators — the RGS proteins
Koelle M. A new family of G-protein regulators — the RGS proteins. Current Opinion In Cell Biology 1997, 9: 143-147. PMID: 9069252, DOI: 10.1016/s0955-0674(97)80055-5.Peer-Reviewed Original ResearchConceptsRGS proteinsInactive GDP-bound formG protein alpha subunitsG proteinsDifferent RGS proteinsHeterotrimeric G proteinsG-protein regulatorsGDP-bound formG protein signalingFirst biochemical studyGenetic experimentsGTPase activityAlpha subunitBiochemical studiesProteinPhysiological significanceRegulatorFamilySubunitsSignalingNew familyLarge number