2018
Predictors and Moderators of Antipsychotic-Related Weight Gain in the Treatment of Early-Onset Schizophrenia Spectrum Disorders Study
Taylor JH, Jakubovski E, Gabriel D, Bloch MH. Predictors and Moderators of Antipsychotic-Related Weight Gain in the Treatment of Early-Onset Schizophrenia Spectrum Disorders Study. Journal Of Child And Adolescent Psychopharmacology 2018, 28: 474-484. PMID: 29920116, PMCID: PMC6154761, DOI: 10.1089/cap.2017.0147.Peer-Reviewed Original ResearchMeta regression: Relationship between antipsychotic receptor binding profiles and side-effects
Olten B, Bloch MH. Meta regression: Relationship between antipsychotic receptor binding profiles and side-effects. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2018, 84: 272-281. PMID: 29410000, DOI: 10.1016/j.pnpbp.2018.01.023.Peer-Reviewed Original ResearchConceptsRisk of sedationExtrapyramidal side effectsM4 receptorsReceptor binding profileWeight gainAntipsychotic medicationSide effectsGeneric inverse variance methodReceptor affinityAffinity of antipsychoticsIndividual antipsychotic medicationsInverse variance methodTreatment of schizophreniaExtrapyramidal symptomsQTc prolongationM1 receptorsProlactin increaseQT prolongationAntipsychotic agentsH1 receptorsHigh riskMedicationsSedationBinding profileReceptors
2017
M13. Identifying Youths at Risk for Antipsychotic-Induced Weight Gain and Metabolic Dysfunction in the Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS)
Taylor J, Jakubovski E, Gabriel D, Bloch M. M13. Identifying Youths at Risk for Antipsychotic-Induced Weight Gain and Metabolic Dysfunction in the Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS). Schizophrenia Bulletin 2017, 43: s215-s216. PMCID: PMC5475770, DOI: 10.1093/schbul/sbx022.012.Peer-Reviewed Original Research