2024
Safety Profile Comparison of 2 Smooth Tissue Expander Types
Almeida M, Alper D, Williams M, Shah R, Ihnat J, Hu K, Parikh N, Alperovich M. Safety Profile Comparison of 2 Smooth Tissue Expander Types. Annals Of Plastic Surgery 2024, 93: 178-182. PMID: 38980932, DOI: 10.1097/sap.0000000000004019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTissue ExpansionTissue Expansion DevicesTreatment OutcomeConceptsBody mass indexComplication rateDrain durationMass indexAcellular dermal matrix useRetrospective review of patientsReview of patientsHigher body mass indexSmooth tissue expandersPain scoresChemotherapy exposureRetrospective reviewCapsular contractureSmooth implantsSafety profileWound breakdownFilling volumePatient comorbiditiesPerioperative informationCancer characteristicsMultivariate analysisComplicationsTissue expanderRadiation exposureMatrix use
2020
Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation
Heller DR, Zhuo H, Zhang Y, Parikh N, Fusi S, Alperovich M, Lannin DR, Higgins SA, Avraham T, Killelea BK. Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation. Annals Of Surgical Oncology 2020, 28: 2169-2179. PMID: 32974699, DOI: 10.1245/s10434-020-09122-0.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsFemaleFollow-Up StudiesHumansMammaplastyMastectomyPostoperative ComplicationsRadiotherapy, AdjuvantRetrospective StudiesTreatment OutcomeConceptsPostmastectomy radiation therapyLarge institutional cohortProbability of complicationsImmediate autologous reconstructionAutologous reconstructionMultivariable analysisInstitutional cohortFlap outcomesRadiation-related complicationsRisk of complicationsChest wall asymmetryMethodsMedical recordsNodal radiationMedian followNeoadjuvant chemotherapyPrimary endpointResultsOne hundredSurgical outcomesFat necrosisFlap complicationsImmediate reconstructionReoperationRadiation therapyComplicationsFat graftingDoes Surgical Specialty Impact Mandibular Fracture Outcomes?
Sun A, Nguyen K, Mehta SK, Allam O, Park KE, Alperovich M. Does Surgical Specialty Impact Mandibular Fracture Outcomes? Journal Of Craniofacial Surgery 2020, 32: 855-858. PMID: 32941216, DOI: 10.1097/scs.0000000000007046.Peer-Reviewed Original ResearchMeSH KeywordsAdultHumansMandibleMandibular FracturesPatient ReadmissionPostoperative ComplicationsRetrospective StudiesSurgery, PlasticConceptsReoperation rateReadmission ratesFracture managementInfection rateNational Surgical Quality Improvement ProgramHigher ASA class patientsSurgical Quality Improvement ProgramComparable perioperative outcomesLength of staySignificant differencesQuality Improvement ProgramHigh ratePRS patientsPerioperative outcomesPatient agePatient demographicsFracture outcomesOperative timeENT patientsAdverse outcomesClass patientsMaxillofacial traumaPractice patternsPatientsPRS groupWorse overall health status negatively impacts satisfaction with breast reconstruction
Mehta SK, Olawoyin O, Chouairi F, Duy PQ, Mets EJ, Gabrick KS, Le NK, Avraham T, Alperovich M. Worse overall health status negatively impacts satisfaction with breast reconstruction. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 73: 2056-2062. PMID: 32972879, DOI: 10.1016/j.bjps.2020.08.093.Peer-Reviewed Original ResearchConceptsBREAST-Q scoresPatient-reported outcomesOverall health statusBreast reconstructionOverall healthASA classificationHealth statusGeneral linear modelAnesthesiologists physical status classificationYale-New Haven HospitalWorse overall health statusBREAST-Q outcomesHealth-related qualityPhysical status classificationNew Haven HospitalEffect of ASAASA 1Independent predictorsPatient factorsPostoperative satisfactionBreast surgeryPatient satisfactionASA 2PatientsRelevant covariatesRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean duration
2019
Breast reconstruction patterns and outcomes in academic and community practices within a single institution
Gabrick K, Alperovich M, Chouari F, Mets EJ, Reinhart M, Dinis J, Avraham T. Breast reconstruction patterns and outcomes in academic and community practices within a single institution. The Breast Journal 2019, 26: 924-930. PMID: 31788914, DOI: 10.1111/tbj.13693.Peer-Reviewed Original ResearchMeSH KeywordsAgedBreast NeoplasmsFemaleHumansMammaplastyMastectomyMedicareRetrospective StudiesUnited StatesConceptsYale-New Haven HospitalBreast reconstructionMore patientsSingle institutionPlastic surgeonsCommercial insuranceHigh rateRetrospective chart reviewPrevalence of diabetesSimilar complication ratesNipple-sparing mastectomyHigher infection rateAP cohortChart reviewComplication rateCP cohortPostoperative outcomesPreoperative historySurgery ratesPsychiatric comorbidityInsurance statusAutologous reconstructionPractice patternsMedicaid patientsGreater prevalenceVeau III and Veau IV Cleft Palate: Do Peri-Operative Complications Differ?
Chouairi F, Mets EJ, Gabrick KS, Alperovich M. Veau III and Veau IV Cleft Palate: Do Peri-Operative Complications Differ? Journal Of Craniofacial Surgery 2019, 30: 2372-2374. PMID: 31584550, DOI: 10.1097/scs.0000000000005918.Peer-Reviewed Original ResearchHead and Neck Reconstructive Surgery: Characterization of the One-Team and Two-Team Approaches
Torabi SJ, Chouairi F, Dinis J, Alperovich M. Head and Neck Reconstructive Surgery: Characterization of the One-Team and Two-Team Approaches. Journal Of Oral And Maxillofacial Surgery 2019, 78: 295-304. PMID: 31622570, DOI: 10.1016/j.joms.2019.09.011.Peer-Reviewed Original ResearchMeSH KeywordsFree Tissue FlapsHead and Neck NeoplasmsHumansPlastic Surgery ProceduresPostoperative ComplicationsRetrospective StudiesRisk FactorsConceptsLonger operative timeMicrovascular free flapsOperative timeReconstructive surgeryFree flapNational Surgical Quality Improvement ProgramPropensity scoreSurgical Quality Improvement ProgramOperating roomHigher American SocietyIncidence of complicationsRate of complicationsNeck reconstructive surgeryLength of stayComplicated reconstructive proceduresQuality Improvement ProgramConcurrent headNeck OncosurgeryAnesthesiologists classificationPostoperative staySurgery groupComplication rateReconstructive headRetrospective studyNeck proceduresAirway Analysis in Apert Syndrome.
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Airway Analysis in Apert Syndrome. Plastic & Reconstructive Surgery 2019, 144: 704-709. PMID: 31461034, DOI: 10.1097/prs.0000000000005937.Peer-Reviewed Original ResearchMeSH KeywordsAcrocephalosyndactyliaChildChild, PreschoolFemaleHumansInfantLarynxMaleNasopharynxRetrospective StudiesConceptsPosterior nasal spineApert syndromeNasal spineTomographic scanPharyngeal airway volumeRespiratory insufficiencyAirway compromiseAirway volumeAirway spaceRespiratory impairmentClinical managementAirway analysisPosterior airwayNasal cavityDisease comorbiditiesPatientsSyndromeSkull baseNasal measurementsSpine distanceStatistical significanceMidfacial deformitiesSpineAirwayPharyngeal regionNational 30-Day Outcomes for Posterior Cranial Vault Distraction
Chouairi F, Torabi SJ, Alperovich M. National 30-Day Outcomes for Posterior Cranial Vault Distraction. Journal Of Craniofacial Surgery 2019, Publish Ahead of Print: &na;. PMID: 30807468, DOI: 10.1097/scs.0000000000005285.Peer-Reviewed Original ResearchMeSH KeywordsCraniosynostosesFemaleHumansInfantMaleOsteogenesis, DistractionRetrospective StudiesSkullTreatment OutcomeConceptsPosterior vault distractionOperative timePediatric databaseNational Surgical Quality Improvement Program Pediatric databaseCalvarial volumeBlood transfusion volumeIncidence of strokeMajority of patientsSurgical site infectionPosterior cranial vault distractionNational pediatric databaseTransfusion requirementsTransfusion volumeOlder patientsPerioperative outcomesBlood transfusionPatient ageSite infectionPatient backgroundSafety profileSafe procedureRisk factorsInclusion criteriaPatient profilesPatientsComplication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction
Chouairi F, Gabrick KS, Avraham T, Markov NP, Alperovich M. Complication Profiles by Mastectomy Indication in Tissue Expander Breast Reconstruction. Plastic & Reconstructive Surgery 2019, Publish Ahead of Print: &na;. PMID: 30730496, DOI: 10.1097/prs.0000000000005423.Peer-Reviewed Original ResearchConceptsMastectomy flap necrosisTwo-stage implant breast reconstructionImplant breast reconstructionFlap necrosisBreast reconstructionHigh riskProphylactic mastectomyTherapeutic mastectomyMastectomy indicationExact testTissue expander breast reconstructionCLINICAL QUESTION/LEVELYale-New Haven HospitalPermanent implant reconstructionExpander breast reconstructionTimes higher riskFisher's exact testNew Haven HospitalSignificant differencesBreast reconstruction proceduresBinary logistic regressionReconstructive complicationsBreast groupPerioperative complicationsComplication rateSpatial and temporal changes of midface in Apert’s syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Spatial and temporal changes of midface in Apert’s syndrome. Journal Of Plastic Surgery And Hand Surgery 2019, 53: 130-137. PMID: 30782083, DOI: 10.1080/2000656x.2018.1541324.Peer-Reviewed Original Research
2018
National Longitudinal Comparison of Patients Undergoing Surgical Management of Craniosynostosis
Wu RT, Shultz BN, Gabrick KS, Abraham PF, Cabrejo R, Persing JA, Alperovich M. National Longitudinal Comparison of Patients Undergoing Surgical Management of Craniosynostosis. Journal Of Craniofacial Surgery 2018, 29: 1755-1759. PMID: 30095569, DOI: 10.1097/scs.0000000000004775.Peer-Reviewed Original ResearchConceptsCranial vault remodelingCVR patientsLength of stayPrivate insuranceStrip craniectomyInpatient DatabaseCraniectomy patientsVault remodelingKids' Inpatient DatabaseNonsyndromic craniosynostosis patientsCraniosynostosis managementInsurancePostsurgical complicationsSurgical managementHospital chargesTreatment optionsLongitudinal comparisonHospital characteristicsSerum transfusionMedicaid patientsAccidental punctureSurgical preferenceCraniectomyPatientsMultivariate analysisEvolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy
Frey JD, Stranix JT, Chiodo MV, Alperovich M, Ahn CY, Allen RJ, Choi M, Karp NS, Levine JP. Evolution in Monitoring of Free Flap Autologous Breast Reconstruction after Nipple-Sparing Mastectomy. Plastic & Reconstructive Surgery 2018, 141: 1086-1093. PMID: 29659449, DOI: 10.1097/prs.0000000000004271.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreastBreast NeoplasmsFemaleFree Tissue FlapsHumansMammaplastyMastectomy, SubcutaneousMiddle AgedNipplesPatient SatisfactionPerforator FlapPostoperative CarePostoperative ComplicationsReoperationRetrospective StudiesTransplantation, AutologousTreatment OutcomeUltrasonography, DopplerConceptsNipple-sparing mastectomyFree flap reconstructionSkin paddleFlap reconstructionAutologous reconstructionRevision proceduresMuscle-sparing transverse rectus abdominis myocutaneous flapFree flap autologous breast reconstructionAutologous free flap reconstructionTransverse rectus abdominis myocutaneous flapGreater body mass indexCLINICAL QUESTION/LEVELPercentage of flapsProfunda artery perforatorRectus abdominis myocutaneous flapAutologous breast reconstructionBody mass indexInferior epigastric perforatorGreater mean numberMass indexFlap weightMastectomy weightComparing outcomesBreast reconstructionMastectomy reconstruction
2016
Outpatient Alveolar Bone Grafting
Farber SJ, Runyan CM, Stern MJ, Massie JP, Alperovich M, Flores RL. Outpatient Alveolar Bone Grafting. Journal Of Craniofacial Surgery 2016, 27: 1661-1664. PMID: 27438449, DOI: 10.1097/scs.0000000000002899.Peer-Reviewed Original ResearchConceptsAlveolar bone graftTotal direct costsVariable direct costsInpatient stayObservation groupSite painDirect costsOutpatient costsRetrospective single-institution reviewDonor site painGroup of patientsSame-day dischargeSingle-institution reviewPostoperative inpatient stayOperating room costsCost-efficient treatmentHospital stayInpatient costsOutpatient groupTrephine techniqueAlveolar boneABG surgeryBone graftStayRoom costsNasal Septal Anatomy in Skeletally Mature Patients With Cleft Lip and Palate
Massie JP, Runyan CM, Stern MJ, Alperovich M, Rickert SM, Shetye PR, Staffenberg DA, Flores RL. Nasal Septal Anatomy in Skeletally Mature Patients With Cleft Lip and Palate. Facial Plastic Surgery & Aesthetic Medicine 2016, 18: 347-353. PMID: 27227513, DOI: 10.1001/jamafacial.2016.0404.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesCleft LipCleft PalateCone-Beam Computed TomographyFemaleHumansMaleNasal ObstructionNasal SeptumRetrospective StudiesYoung AdultConceptsMature patientsSeptal deviationPosterior nasal spineCleft lipNasal spineAirway obstructionAirway stenosisBony septumCoronal sectionsSingle-center retrospective reviewCartilaginous septumAcademic tertiary referral centerNasal airway anatomySignificant septal deviationAge-matched control individualsTertiary referral centerSkeletally Mature PatientsLe Fort IAnterior nasal spineReferral centerRetrospective reviewCLP groupAirway anatomyMean ageCleft rhinoplastyLong-Term Surgical and Speech Outcomes Following Palatoplasty in Patients With Treacher–Collins Syndrome
Golinko MS, LeBlanc EM, Hallett AM, Alperovich M, Flores RL. Long-Term Surgical and Speech Outcomes Following Palatoplasty in Patients With Treacher–Collins Syndrome. Journal Of Craniofacial Surgery 2016, 27: 1408-1411. PMID: 27607112, DOI: 10.1097/scs.0000000000002821.Peer-Reviewed Original ResearchConceptsTreacher Collins syndromeVelopharyngeal dysfunctionCleft palateSurgical outcomesSpeech outcomesSpeech pathologistsCleft palate typeChallenging patient populationMajority of patientsCleft palate repairTime of palatoplastyLong-term speechPruzansky classificationVeau IVeau IIVeau IIIFurther surgeryPharyngeal surgeryUnderwent repairRetrospective reviewPatient populationSingle institutionPalate repairHigh incidencePatients“Breast in a Day”
Choi M, Frey JD, Alperovich M, Levine JP, Karp NS. “Breast in a Day”. Plastic & Reconstructive Surgery 2016, 138: 184e-191e. PMID: 27465178, DOI: 10.1097/prs.0000000000002333.Peer-Reviewed Original ResearchConceptsPermanent implant reconstructionNipple-sparing mastectomyMastectomy flap necrosisImplant reconstructionAcellular dermal matrixComplication rateFlap necrosisMajor mastectomy flap necrosisMinor mastectomy flap necrosisDermal matrixImplant sizeCLINICAL QUESTION/LEVELPercent of reconstructionsCommon major complicationPrior radiation therapyGreater complication rateLow complication rateNipple-sparing mastectomiesBody mass indexCommon minor complicationAverage implant sizeMajority of implantsOverall complicationsNipple necrosisMinor complicationsApplying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair
Alperovich M, Frey JD, Potts MB, Riina HA, Staffenberg DA. Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair. Journal Of Craniofacial Surgery 2016, 27: 1077-1079. PMID: 27192638, DOI: 10.1097/scs.0000000000002643.Peer-Reviewed Original ResearchConceptsCraniofacial principlesNeurosurgical exposureCraniofacial surgeonsZygomaticomaxillary complex fracturesSuperior cosmetic resultsAnterior skull baseRisk of injuryAneurysm repairNerve transectionCosmetic resultsFacial nerveEyebrow incisionPeriorbital surgeryFrontal branchSkull baseConspicuous scarringTranspalpebral approachComplex fracturesNeurosurgical literatureSeries experienceSurgeonsCraniofacial surgerySurgeryCraniotomyExposure
2015
Nipple‐sparing Mastectomy and Sub‐areolar Biopsy: To Freeze or not to Freeze? Evaluating the Role of Sub‐areolar Intraoperative Frozen Section
Alperovich M, Choi M, Karp NS, Singh B, Ayo D, Frey JD, Roses DF, Schnabel FR, Axelrod DM, Shapiro RL, Guth AA. Nipple‐sparing Mastectomy and Sub‐areolar Biopsy: To Freeze or not to Freeze? Evaluating the Role of Sub‐areolar Intraoperative Frozen Section. The Breast Journal 2015, 22: 18-23. PMID: 26510917, DOI: 10.1111/tbj.12517.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyIntraoperative frozen sectionNipple-sparing mastectomiesNipple-areolar complexPermanent paraffin sectionsFrozen sectionsParaffin sectionsBreast cancer resectionRecords of patientsFrozen section resultsCancer resectionDuctal carcinomaProphylactic mastectomyResidual pathologyBreast reconstructionPermanent biopsyMastectomyBiopsyReconstructive planningSeparate proceduresResectionPatientsCarcinomaBreast