2024
The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis.
Alper D, Almeida M, Hu K, Yang J, Timberlake A, Shah J, Persing J, Alperovich M. The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis. Journal Of Neurosurgery Pediatrics 2024, 34: 234-245. PMID: 38875721, DOI: 10.3171/2024.4.peds23510.Peer-Reviewed Original ResearchBehavioral outcomesNonsyndromic sagittal synostosisSocial Responsiveness Scale-2nd editionBehavior Rating InventoryAttention-deficit/hyperactivity disorderSagittal synostosisPly geneRelative to controlsExecutive functionAttention-deficit/hyperactivityExternalizing behaviorsExternalizing problemsLoss of functionBehavior problemsASD domainAssociated with worse scoresOutcomes of patientsRule-breakingParents of children aged 6Treating sagittal synostosisOlder ageAssociation of mutationsBehavior scoresSociodemographic factorsPly groups
2020
Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologies
2019
What is the Functional Difference Between Sagittal With Metopic and Isolated Sagittal Craniosynotosis?
Cabrejo R, Lacadie C, Chuang C, Yang J, Sun A, Brooks E, Beckett J, Eilbott J, Gabrick K, Steinbacher D, Alperovich M, Pelphrey K, Ventola P, Constable T, Persing JA. What is the Functional Difference Between Sagittal With Metopic and Isolated Sagittal Craniosynotosis? Journal Of Craniofacial Surgery 2019, 30: 968-973. PMID: 30882572, DOI: 10.1097/scs.0000000000005288.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingFunctional magnetic resonance imagingISC groupInfant patientsFunctional brain connectivityMagnetic resonance imagingResting-state functional connectivity MRI dataDTI dataWhite matter microstructureCerebrospinal fluidFMRIB Software LibraryResonance imagingSagittal synostosisSagittal craniosynostosisMetopic synostosisPatientsTensor imagingBrain connectivityMetopic craniosynostosisSMC groupFMRI imagingSignificant differencesSynostosisSagittalMRI data