2016
Pathogenesis of Korean SapelovirusA in piglets and chicks
Kim D, Kang M, Son K, Bak G, Park J, Hosmillo M, Seo J, Kim J, Alfajaro M, Soliman M, Baek Y, Cho E, Lee J, Kwon J, Choi J, Goodfellow I, Cho K. Pathogenesis of Korean SapelovirusA in piglets and chicks. Journal Of General Virology 2016, 97: 2566-2574. PMID: 27487773, PMCID: PMC5078829, DOI: 10.1099/jgv.0.000571.Peer-Reviewed Original ResearchConceptsExtra-intestinal organsHigher viral RNA levelsNon-suppurative myelitisViral RNA levelsReal-time reverse transcription PCRCells of pigsIntestinal pathologyReverse transcription-PCRViral antigensViral pathogenesisReproductive disordersSapelovirus APathogenesisPorcine sapelovirusVirus entryCultured cell linesRNA levelsEpithelial cellsTranscription-PCRFecal samplesPigletsPneumoniaCell linesSialic acidPathology
2013
Different virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves
Park J, Kim H, Matthijnssens J, Alfajaro M, Kim D, Son K, Kwon H, Hosmillo M, Ryu E, Kim J, Cena R, Lee J, Kang M, Park S, Cho K. Different virulence of porcine and porcine-like bovine rotavirus strains with genetically nearly identical genomes in piglets and calves. Veterinary Research 2013, 44: 88. PMID: 24083947, PMCID: PMC3851489, DOI: 10.1186/1297-9716-44-88.Peer-Reviewed Original ResearchConceptsHistopathological changesSmall intestineGroup A rotavirusesDirect interspecies transmissionGenotype constellationCritical molecular determinantsFull-length sequencing analysisA rotavirusesBovine rotavirusVP1-VP4Pathological phenotypesDifferent virulencePigletsDiarrheaInterspecies transmissionAmino acid mutationsRotavirusCalvesIntestineSpecific mutationsTropismMolecular determinantsSequencing analysisUntranslated regionPorcine