2016
A Chronic Opioid Therapy Dose Reduction Policy in Primary Care
Weimer MB, Hartung DM, Ahmed S, Nicolaidis C. A Chronic Opioid Therapy Dose Reduction Policy in Primary Care. Substance Use & Addiction Journal 2016, 37: 141-147. PMID: 26685018, DOI: 10.1080/08897077.2015.1129526.Peer-Reviewed Original ResearchConceptsHigh-dose opioidsChronic opioid therapyOpioid therapyOpioid doseDose taperAcademic primary care clinicHigh-dose opioid therapyHigher opioid doseIntervention of educationOpioid dose reductionTotal opioid doseRetrospective cohort studyCharacteristics of patientsPrimary care clinicsOpioid use disorderMedication-assisted treatmentAverage daily doseOnly significant associationMorphine equivalentsOpioid dosesCohort studyPatient characteristicsDaily doseCare clinicsChronic pain
2014
Methadone Overdose and Cardiac Arrhythmia Potential: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline
Chou R, Weimer MB, Dana T. Methadone Overdose and Cardiac Arrhythmia Potential: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline. Journal Of Pain 2014, 15: 338-365. PMID: 24685459, DOI: 10.1016/j.jpain.2014.01.495.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsArrhythmias, CardiacChronic PainDrug OverdoseHumansMethadoneOpioid-Related DisordersPractice Guidelines as TopicConceptsAmerican Pain SocietyMethadone useChronic painPain SocietyClinical guidelinesArrhythmia potentialDependence Clinical Practice GuidelineMethadone-related deathsQTc interval prolongationUse of methadoneClinical practice guidelinesCardiac arrhythmia riskMarked increaseNumber of deathsMethadone safetyMortality benefitCardiac riskInterval prolongationOpioid dependenceQTc intervalAdverse outcomesCochrane LibraryMethadone overdoseCase reportPsychiatric admissions
2011
The Source of Methadone in Overdose Deaths in Western Virginia in 2004
Weimer MB, Korthuis PT, Behonick GS, Wunsch MJ. The Source of Methadone in Overdose Deaths in Western Virginia in 2004. Journal Of Addiction Medicine 2011, 5: 188-202. PMID: 21844834, PMCID: PMC3156987, DOI: 10.1097/adm.0b013e318211c56a.Peer-Reviewed Original ResearchConceptsSource of methadoneOpioid treatment programsMethadone-related deathsOverdose deathsMethadone-related overdose deathsUnintentional poisoning deathsPrescription monitoring programsMajority of deathsCause of deathMedical examiner casesIllicit methadone useChief Medical ExaminerMethadone usePrescription opioidsPoisoning deathsNonprescription useMethadoneTreatment programNonmedical useDeathDecedentsMedical examinersRural VirginiaCurrent studyAnalgesia