2024
The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review
Jegede O, De Aquino J, Hsaio C, Caldwell E, Funaro M, Petrakis I, Muvvala S. The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review. Journal Of Addiction Medicine 2024, 18: 499-510. PMID: 39356620, PMCID: PMC11449257, DOI: 10.1097/adm.0000000000001356.Peer-Reviewed Original ResearchNonmedical opioid useOpioid use disorderOpioid useWithdrawal symptomsTreatment outcomesSymptoms prior to treatmentUse disorderRisk of precipitated withdrawalLow-dose buprenorphineSynthetic opioidsPotency synthetic opioidsConclusions Current evidencePrecipitated withdrawalRisk of overdoseDosing strategiesPharmacological interactionsClinical significanceDecreased riskWeb of ScienceOpioidInclusion criteriaCurrent evidenceClinical implicationsMOUDPainA review of the kappa opioid receptor system in opioid use
Cayir S, Zhornitsky S, Barzegary A, Sotomayor-Carreño E, Sarfo-Ansah W, Funaro M, Matuskey D, Angarita G. A review of the kappa opioid receptor system in opioid use. Neuroscience & Biobehavioral Reviews 2024, 162: 105713. PMID: 38733895, DOI: 10.1016/j.neubiorev.2024.105713.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsKappa opioid receptor systemKappa-opioid receptorsOUD subjectsKappa-opioid receptor expressionOpioid withdrawal symptomsWithdrawal symptomsDynorphin levelsPeripheral blood lymphocytesOpioid useDrug-seeking/taking behaviorAnti-reward systemsKappa-opioid receptor antagonistClinical studiesCerebrospinal fluidOpioid receptor systemKOR/dynorphin systemDisorder subjectsOpioid receptorsOpioid intoxicationBlood lymphocytesReceptor systemOpioidWeb of ScienceClinical roleDynorphin
2023
Weight change among patients engaged in medication treatment for opioid use disorder: a scoping review
Carr M, Lou R, Macdonald-Gagnon G, Peltier M, Funaro M, Martino S, Masheb R. Weight change among patients engaged in medication treatment for opioid use disorder: a scoping review. The American Journal Of Drug And Alcohol Abuse 2023, 49: 551-565. PMID: 37200510, PMCID: PMC10840392, DOI: 10.1080/00952990.2023.2207720.Peer-Reviewed Original ResearchConceptsOpioid use disorderExcess weight gainWeight gainMedication treatmentUse disordersType of MOUDBuprenorphine/naloxoneRetrospective chart reviewUse of methadoneBody mass indexModerate weight gainMOUD initiationChart reviewCohort studyOpioid useBuprenorphine/Mass indexMedication doseMethadone treatmentNonrandomized studyCase reportEthnic disparitiesPotential associationMOUDPatients
2021
An Evaluation of Opioid Use in Black Communities: A Rapid Review of the Literature.
Jordan A, Mathis M, Haeny A, Funaro M, Paltin D, Ransome Y. An Evaluation of Opioid Use in Black Communities: A Rapid Review of the Literature. Harvard Review Of Psychiatry 2021, 29: 108-130. PMID: 33666395, PMCID: PMC8335706, DOI: 10.1097/hrp.0000000000000285.Peer-Reviewed Original ResearchConceptsOpioid useRapid reviewSocial determinantsUse of opioidsTreatment-seeking patternsClear inclusion criteriaOpioid overdose deathsFull-text reviewComprehensive search strategyHealth care systemGrey literature sourcesClinician prescribingTreatment initiationInclusion criteriaOverdose deathsEpidemiologic SurveyClinical practiceHealth outcomesOpioid crisisOpioidsNarrative summaryTraditional health care systemCare systemSystematic review methodsBlack individuals
2019
Integration of care for HIV and opioid use disorder
Oldfield B, Muñoz N, McGovern M, Funaro M, Villanueva M, Tetrault J, Edelman E. Integration of care for HIV and opioid use disorder. AIDS 2019, Publish Ahead of Print: &na;. PMID: 30882491, PMCID: PMC6588508, DOI: 10.1097/qad.0000000000002125.Peer-Reviewed Original ResearchConceptsHIV care settingsCare settingsClinical benefitTreatment settingsSystematic reviewBuprenorphine/naloxoneOpioid use disorderProvision of medicationsIntegration of careAntiretroviral therapyOpioid useMedication adherencePROSPERO databaseOvid MEDLINETreatment strategiesObservational studyHIVUse disordersModerate riskBehavioral interventionsScreening strategyOUDRisk reductionTreatmentUnique studies