2021
Neighborhood and Individual Socioeconomic Disadvantage and Survival Among Patients With Nonmetastatic Common Cancers
Cheng E, Soulos PR, Irwin ML, Feliciano E, Presley CJ, Fuchs CS, Meyerhardt JA, Gross CP. Neighborhood and Individual Socioeconomic Disadvantage and Survival Among Patients With Nonmetastatic Common Cancers. JAMA Network Open 2021, 4: e2139593. PMID: 34919133, PMCID: PMC8683967, DOI: 10.1001/jamanetworkopen.2021.39593.Peer-Reviewed Original ResearchConceptsCancer-specific mortalityNeighborhood socioeconomic statusIndividual-level socioeconomic statusIndividual socioeconomic statusColorectal cancerOverall mortalitySocioeconomic statusCohort studyHazard ratioDual eligibilityCancer patientsCommon cancerLung cancerProstate cancerSocioeconomic disadvantageHigh riskEnd Results-Medicare databaseMedicare-Medicaid dual eligibilityPopulation-based cohort studyCox proportional hazards regressionSuboptimal cancer careColorectal cancer patientsBreast cancer patientsProportional hazards regressionNon-Hispanic white individualsGenetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome‐wide association study
Wang Z, Budhu AS, Shen Y, Wong LL, Hernandez BY, Tiirikainen M, Ma X, Irwin ML, Lu L, Zhao H, Lim JK, Taddei T, Mishra L, Pawlish K, Stroup A, Brown R, Nguyen MH, Koshiol J, Hernandez MO, Forgues M, Yang H, Lee M, Huang Y, Iwasaki M, Goto A, Suzuki S, Matsuda K, Tanikawa C, Kamatani Y, Mann D, Guarnera M, Shetty K, Thomas CE, Yuan J, Khor CC, Koh W, Risch H, Wang XW, Yu H. Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome‐wide association study. JGH Open 2021, 5: 1363-1372. PMID: 34950780, PMCID: PMC8674550, DOI: 10.1002/jgh3.12682.Peer-Reviewed Original ResearchNonalcoholic fatty liver diseaseCase-control studyHepatocellular carcinomaSingle nucleotide polymorphismsChronic hepatitis C virus (HCV) infectionHepatitis C virus infectionGenetic susceptibilityC virus infectionLong-term alcohol useFatty liver diseaseUS case-control studyBody mass indexMajor risk factorGenome-wide association studiesHCV infectionCohort studyLiver diseaseCigarette smokingMass indexRisk factorsHCC casesVirus infectionGene-environment interactionsUS populationDisease riskAnalysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database
Cheng E, Blackburn HN, Ng K, Spiegelman D, Irwin ML, Ma X, Gross CP, Tabung FK, Giovannucci EL, Kunz PL, Llor X, Billingsley K, Meyerhardt JA, Ahuja N, Fuchs CS. Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database. JAMA Network Open 2021, 4: e2112539. PMID: 34132794, PMCID: PMC8209612, DOI: 10.1001/jamanetworkopen.2021.12539.Peer-Reviewed Original ResearchConceptsEarly-onset colorectal cancerOnset colorectal cancerNational Cancer DatabaseColorectal cancerAge 51Overall survivalCancer DatabaseIncidence of CRCCox proportional hazards regressionPrimary colorectal cancerKaplan-Meier analysisProportional hazards regressionAge 50 yearsAge 25 yearsAnalysis of survivalCohort studySurvival benefitHazards regressionUnadjusted analysesCancer incidenceMAIN OUTCOMEAge 35Survival advantageLower riskStage I
2015
Weight Gain After Breast Cancer Diagnosis and All-Cause Mortality: Systematic Review and Meta-Analysis
Playdon MC, Bracken MB, Sanft TB, Ligibel JA, Harrigan M, Irwin ML. Weight Gain After Breast Cancer Diagnosis and All-Cause Mortality: Systematic Review and Meta-Analysis. Journal Of The National Cancer Institute 2015, 107: djv275. PMID: 26424778, PMCID: PMC4715249, DOI: 10.1093/jnci/djv275.Peer-Reviewed Original ResearchConceptsBody mass indexBreast cancer-specific mortalityCancer-specific mortalityCause mortalityWeight gainBreast cancer diagnosisBreast cancerStage I-IIIC breast cancerSystematic reviewPrediagnosis body mass indexWomen age 18 yearsPostdiagnosis weight gainCancer diagnosisCause mortality ratesBreast cancer mortalityAge 18 yearsWeb of ScienceCohort studyRecurrence outcomesMass indexCancer mortalityClinical trialsHigh riskMortality rateBody weight
2005
A Prospective Cohort Study Of Physical Activity In Relation To Disease-free Survival Of Breast Cancer In Women Diagnosed With Breast Cancer
Irwin M, McTiernan A, Baumgartner R, Baumgartner K, Bernstein L, Gilliland F, Ballard-Barbash R. A Prospective Cohort Study Of Physical Activity In Relation To Disease-free Survival Of Breast Cancer In Women Diagnosed With Breast Cancer. Medicine & Science In Sports & Exercise 2005, 37: s358. DOI: 10.1097/00005768-200505001-01878.Peer-Reviewed Original ResearchA Prospective Cohort Study Of Physical Activity In Relation To Disease-free Survival Of Breast Cancer In Women Diagnosed With Breast Cancer
Irwin M, McTiernan A, Baumgartner R, Baumgartner K, Bernstein L, Gilliland F, Ballard-Barbash R. A Prospective Cohort Study Of Physical Activity In Relation To Disease-free Survival Of Breast Cancer In Women Diagnosed With Breast Cancer. Medicine & Science In Sports & Exercise 2005, 37: s358. DOI: 10.1249/00005768-200505001-01878.Peer-Reviewed Original Research