2005
Utilization of Healthcare Resources in Obstructive Sleep Apnea Syndrome: a 5Year Follow-Up Study in Men Using CPAP
Albarrak M, Banno K, Al. Sabbagh AA, Delaive K, Walld R, Manfreda J, Kryger MH. Utilization of Healthcare Resources in Obstructive Sleep Apnea Syndrome: a 5Year Follow-Up Study in Men Using CPAP. Sleep 2005, 28: 1306-1311. PMID: 16295216, DOI: 10.1093/sleep/28.10.1306.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeSleep apnea syndromeIschemic heart diseaseHealthcare utilizationApnea syndromeHeart diseaseTreatment of OSASContinuous positive airway pressure useUntreated obstructive sleep apnea syndromeRetrospective observational cohort studyPositive airway pressure useEpworth Sleepiness Scale scoreLong-term health benefitsHigher healthcare utilizationObservational cohort studyApnea-hypopnea indexBody mass indexCPAP treatmentCohort studyPhysician visitsMass indexEligible menOSAS diagnosisFifth yearOSA diagnosisLong-term treatment of sleep breathing disorder in a patient with Huntington's disease
Banno K, Hobson DE, Kryger MH. Long-term treatment of sleep breathing disorder in a patient with Huntington's disease. Parkinsonism & Related Disorders 2005, 11: 261-264. PMID: 15878590, DOI: 10.1016/j.parkreldis.2005.01.005.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureSleep breathing disordersApnea-hypopnea indexBreathing disordersHuntington's diseaseRapid eye movement (REM) sleepPositive airway pressureObstructive sleep apneaLong-term treatmentEye movement sleepQuality of lifeAutosomal dominant neurodegenerative disorderAirway pressureHD patientsSleep apneaRespiratory arousalsMovement sleepDominant neurodegenerative disorderDaytime alertnessSleep structureNeurodegenerative disordersDiseaseDisordersApneaPatients
2002
Cardiovascular medication use in patients with undiagnosed obstructive sleep apnoea
Otake K, Delaive K, Walld R, Manfreda J, Kryger M. Cardiovascular medication use in patients with undiagnosed obstructive sleep apnoea. Thorax 2002, 57: 417. PMID: 11978918, PMCID: PMC1746332, DOI: 10.1136/thorax.57.5.417.Peer-Reviewed Original ResearchConceptsMore daily dosesCardiovascular diseaseSystemic hypertensionMedication usePrescribed medicationsDaily dosesMore prescriptionsOdds ratioSleep apnoea/hypopnoea syndromeUndiagnosed obstructive sleep apnoeaObstructive sleep apnoeaCardiovascular medication useCongestive heart failureUse of medicationsGeneral population controlsOSAS casesMore medicationsSecondary preventionAngina pectorisHeart failureSleep apnoeaMedication costsSuch medicationsMyocardial infarctionOSAS diagnosis
1998
Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients
Pieta J, Miliar T, Zacharias J, Fine A, Kryger M. Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients. Sleep 1998, 21: 617-622. PMID: 9779521, DOI: 10.1093/sleep/21.6.617.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiparkinson AgentsElectromyographyFemaleHumansLegMaleMovementPergolideRestless Legs SyndromeSleep Apnea SyndromesUremiaConceptsRestless legs syndromeLeg movementsRestless legsUremic patientsSubjective improvementTreatment of RLSDouble-blind placebo-controlled crossover studyPlacebo-controlled crossover studyRestless legs symptomsEffects of pergolideContinuous peritoneal dialysisPeriodic limb movementsSmall patient groupsHours of sleepQuality of sleepFirst hourChronic hemodialysisLeg symptomsCrossover studyLegs syndromePeritoneal dialysisIncremental dosesPatient groupSleep architectureSleep disruption
1993
Nocturnal Cluster Headache Associated with Sleep Apnea. A Case Report
Buckle P, Kerr P, Kryger M. Nocturnal Cluster Headache Associated with Sleep Apnea. A Case Report. Sleep 1993, 16: 487-489. PMID: 8378690, DOI: 10.1093/sleep/16.5.487.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep apneaCluster headacheRapid eye movement (REM) sleepChronic cluster headacheEye movement sleepNasal CPAPOxygen desaturationCase reportMovement sleepHeadache AssociatedBackup rateREM sleepTypical headacheHeadacheApneaSleep labFurther treatmentSleepDesaturationTreatmentBiPAPCPAPMedications
1992
Polysomnography in Acutely III Intensive Care Unit Patients
Buckle P, Pouliot Z, Millar T, Kerr P, Kryger M. Polysomnography in Acutely III Intensive Care Unit Patients. CHEST Journal 1992, 102: 288-291. PMID: 1623769, DOI: 10.1378/chest.102.1.288.Peer-Reviewed Original ResearchConceptsCase reportDescriptive studyDouble-blind clinical trialIntensive care unit patientsStudy designCare unit patientsSeries of patientsCase report studySeries of casesUnit patientsCause of diseaseInvestigational protocolsClinical trialsClinical relevanceClinical researchReport studyChestGold standardPatientsReportPolysomnographyTherapyStudy
1991
Central sleep apnoea in congenital muscular dystrophy.
Kryger M, Steljes D, Yee W, Mate E, Smith S, Mahowald M. Central sleep apnoea in congenital muscular dystrophy. Journal Of Neurology Neurosurgery & Psychiatry 1991, 54: 710. PMID: 1940943, PMCID: PMC1014476, DOI: 10.1136/jnnp.54.8.710.Peer-Reviewed Original ResearchConceptsCentral sleep apnoeaSleep-disordered breathingCongenital muscular dystrophyMorning headachesSleep apnoeaNocturnal seizuresCongestive heart failureMuscular dystrophyPulmonary hypertensionClinical weaknessHeart failureExcessive daytimeNeuromuscular syndromeRespiratory dysfunctionNeuromuscular disordersApnoeaHeadacheSeizuresSymptomsBreathingDystrophyHypertensionDysfunctionSyndrome
1990
Cheyne-Stokes respiration in cardiac failure.
Kryger M, Hanly P. Cheyne-Stokes respiration in cardiac failure. Progress In Clinical And Biological Research 1990, 345: 215-24; discussion 224-6. PMID: 2377634.Peer-Reviewed Original Research
1989
Respiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleep
1985
Sleep and Respiration: Terminology and Methodology
West P, Kryger M. Sleep and Respiration: Terminology and Methodology. Clinics In Chest Medicine 1985, 6: 691-712. PMID: 3936667, DOI: 10.1016/s0272-5231(21)00406-8.Chapters
1983
Sighs During Sleep in Adult Humans
Perez-Padilla R, West P, Kryger M. Sighs During Sleep in Adult Humans. Sleep 1983, 6: 234-243. PMID: 6622880, DOI: 10.1093/sleep/6.3.234.Peer-Reviewed Original ResearchConceptsSleep stage changesCentral apneaGreat intersubject variationExpiratory flowRespiratory centerInspiratory flowEMG activityHeart rateRespiratory rateNormal adultsRespiratory cycleSleepIntersubject variationAdult humansRespiratory controlSleep stagesEEG frequenciesStage 1Normal variabilityPrevious breathStage changesSighsArousalHypoventilationApnea